Calcification sign for prediction of benignity in pulmonary nodules: A meta-analysis.

Background: The calcification sign assessed by computed tomography appears to be a potential marker for benignities among patients diagnosed with pulmonary nodules (PNs). The following meta-analysis has been purposefully designed to figure-out the diagnostic value of the calcification signature as a way of identifying benignities from PNs.

Methods: Cochrane Library, Embase and PubMed were considered as a reference to obtain the required data from January 2000 until October 2020.