Analysis of the variation pattern in left upper division veins and establishment of simplified vein models for anatomical segmentectomy.

Background: Three-dimensional computed tomography bronchography and angiography (3D-CTBA) is a powerful tool to analyze pulmonary anatomy. We used 3D-CTBA to analyze variations of the pulmonary veins of the left upper division (LUD) and created a simplified LUD vein model.

Methods: Between January 2019 and October 2019, 124 patients with left-sided pulmonary lesions were admitted and underwent 3D-CTBA prior to surgery.

S-1 plus apatinib followed by salvage esophagectomy for irinotecan-refractory small cell carcinoma of the esophagus: A case report and review of the literature.

Rationale: Small cell carcinoma of the esophagus (SCCE) is an uncommon but lethal disease characterized by dismal prognosis. Only 10% of advanced SCCE patients survive longer than 1 year. Resection is a choice for limited-stage cases, whereas the optimal treatment regimen for primary SCCE is yet to be elucidated.

Neoadjuvant apatinib plus S-1 in locally advanced pulmonary adenocarcinoma: A case report and review of the literature.

Rationale: About one-third of the lung tumors are staged as locally advanced at the time of initial diagnosis; however, the optimal induction treatment before curative resection has not been elucidated. To date, the evidence regarding the preoperative apatinib plus S-1 for locally advanced pulmonary adenocarcinoma is scarce.

Patient Concerns: A 29-year-old female was admitted because of persistent cough, sputum, and chest distress for 2 months.

Next-day discharge following small uniportal thoracoscopic bullectomy assisted with an anchoring suture.

Objective: Manipulating the instruments during uniportal video-assisted thoracoscopic surgery (U-VATS) bullectomy requires a relatively large incision. This study aimed to investigate the feasibility of next-day discharge following U-VATS bullectomy using an anchoring suture.

Methods: A stapler and a scope were inserted through a single incision in the anchoring group.

S-1 plus apatinib as first-line palliative treatment for stage IVB gastroesophageal junction adenocarcinoma: A case report and review of the literature.

Rationale: Apatinib has been proven to significantly prolong the survival of the patients with advanced chemotherapy-refractory gastric cancer. To date, studies on apatinib plus S-1 as first-line palliative therapy for metastatic gastroesophageal junction (GEJ) cancer are rare.

Patient Concerns: A 61-year-old female patient was admitted with dysphagia, significant loss of body weight, and poor performance status.

Preoperative 3D-CT bronchography and angiography facilitates single-direction uniportal thoracoscopic anatomic lobectomy.

Background: Competency in video-assisted thoracoscopic surgery (VATS) lobectomy is estimated to be reached after 50 cases. Preoperative identification of individualized pulmonary vascular drainage is essential for the safe and fluent performance of single-direction uniportal VATS (UVATS) anatomic lobectomy. Digital anatomy models established by three-dimensional computed tomography bronchography and angiography (3D-CTBA) is therefore utilized to accumulate variations of the right upper lobe (RUL) veins, as right upper lobectomy is considered to be the most complicated and challenging procedure.

Prophylactic octreotide does not reduce the incidence of postoperative chylothorax following lobectomy: Results from a retrospective study.

Chylothorax after lobectomy is common, lacking reliable preventive measures. Octreotide is widely used for treatment of chyle leakage, but its role in preventing chylothorax has not been estimated. The aim of this study was to evaluate whether prophylactic octreotide could reduce the incidence of postoperative chylothorax.

Late-onset bronchopleural fistula after lobectomy and adjuvant chemotherapy for lung cancer: A case report and review of the literature.

Rationale: Late-onset bronchopleural fistula (BPF) induced by chemotherapy after lobectomy for lung cancer is rarely reported, lacking reliable preventive approaches. A timely identification and individualized treatment is essential for prognosis.

Patient Concerns: A 52-year-old female patient complained of fever, productive cough, and fatigue 1 week after adjuvant chemotherapy following right lower lobectomy and systemic mediastinal lymph node dissection.

Late-onset chylothorax during chemotherapy after lobectomy for lung cancer: A case report and review of the literature.

Rationale: Chylothorax is usually diagnosed within a few days after lobectomy. Late-onset chylothorax following trauma or thoracic surgery is rare but potentially lethal, lacking reliable preventive methods.

Patient Concerns: A 54-year-old male patient complained of dyspnea during adjuvant chemotherapy on the 35th postoperative day after right middle lobectomy and systemic lymph node dissection (SLND) for lung cancer.

Rs13405728 is associated with slow ovarian response in assisted reproductive technology.

Objective: To explore the association between rs13405728 with slow ovarian response in assisted reproductive technology (ART).

Patients And Methods: 236 women, aged 21 to 35 years, were enrolled and grouped according to their genotypes, The polymorphism of rs13405728 was genotyped by DNA sequencing.

Results: There was no evidence of any difference in anti-Müllerian hormone (AMH), antral follicle count (AFC) among the three genotypes (p>0.

Remote intervention using smartphone for rural women suffering from premenstrual syndrome: A propensity score matched analysis.

Timely treatment of premenstrual syndrome (PMS) is not always available for rural women, because the local medical resources are insufficient. The efficacy of remote intervention by smartphone on PMS has not been confirmed.A retrospective analysis was performed on rural PMS patients between January 2014 and December 2015.

A rare case of cavitary lung cancer complicated with mycotic pneumonia and bullous emphysema: A case report and review of the literature.

Rationale: The accurate diagnosis and staging of cavitary lung cancer is challenging but essential for the choice of therapy; therefore, the differential diagnosis of cystic pulmonary lesions needs to be elucidated.

Patient Concerns: A patient was admitted with multifocal thin-walled cystic lesions in chest computed tomography.

Diagnoses: The patient had been diagnosed as heterogeneous bullous emphysema pathologically about 3 years ago.

A recurrence-free survivor with chemotherapy-refractory small cell lung cancer after pneumonectomy: A case report and review of the literature.

Rationale: The optimal therapeutic regimen for chemotherapy-refractory and node-positive small-cell lung cancer (SCLC) is criticizable for the lack of evidence.

Patient Concerns: A patient with locally advanced SCLC was insensitive to the first-line chemotherapy of etoposide, irinotecan, and cisplatin.

Diagnoses: The patient was diagnosed as SCLC with mediastinal lymph node metastasis by pathological staining.

A rare case of Merkel cell carcinoma presenting as a giant intra-thoracic mass: A case report and review of the literature.

Rationale: Merkel cell carcinoma (MCC) is an aggressive neuroendocrine-derived cutaneous cancer. Ectopic or single metastatic MCC located in thorax is extremely rare; meanwhile, its definite management has not been elucidated yet.

Patient Concerns: A 64-year-old female patient with a giant mass located in her left thorax was presented for stuffy pain of left chest for 6 months and fever for half a month.

Oleanolic Acid Inhibits Colorectal Cancer Angiogenesis by Blocking the VEGFR2 Signaling Pathway.

Background: Angiogenesis is a crucial process that regulated by multiple intracellular signaling pathways including MEK/ERK and JNK/SAPK. Thus, many inhibitors have developed to these pathways as anti-cancer therapeutic strategies. Oleanolic acid (OA) is a natural pentacyclic triterpenoic acid compound that present in various herbal medicines.

A segmental labeling technique for non-intubated thoracoscopic anatomical segmentectomy.

Herein we present a method of pulmonary segmental labeling for non-intubated thoracoscopic segmentectomy assisted with artificial pneumothorax, which is assumed to obtain a significant colored inflation-deflation line between target segment and adjacent normal tissues for precise resection.

A long-term survivor with esophageal melanoma and pulmonary metastasis after single-stage esophagectomy and lobectomy: Case report and literature review.

Rationale: The optimal therapeutic regimen for primary malignant melanoma of the esophagus (PMME) need to be further elucidated. Besides, the efficacy of surgery for PMME with remote metastasis is uncertain for its rarity.

Patient Concerns: Herein a previously healthy patient was admitted for dysphagia and fatigue, without significant weight loss.

Obesity contributes more to increasing ApoB/ApoA1 ratio than hyperandrogenism in PCOS women aged 20-38 years in China.

We investigated the association between the apolipoprotein B (ApoB)/apolipoprotein A1 (ApoA1) ratio and insulin resistance (IR), metabolic syndrome (MS) and its components in Chinese polycystic ovary syndrome (PCOS) adults. We also examined whether hyperandrogenism is involved in obesity-related metabolic abnormalities in a cohort of patients. A clinical cross-sectional study consisting of 532 Chinese PCOS adults aged 20-38 years was designed.

Single-stage nonintubated uniportal thoracoscopic resection of synchronous bilateral pulmonary nodules after coil labeling: A case report and literature review.

Rationale: Preoperative localization of small pulmonary nodules is essential for precise resection, besides, the optimal treatment for pulmonary nodules is controversial and the prognosis without surgery is uncertain.

Patient Concerns: Herein we present a patient with compromised pulmonary function harboring synchronous triple ground-glass nodules located separately in different pulmonary lobes.

Diagnoses: The pathological diagnosis of the nodules were chronic inflammation, inflammatory pseudotumor and atypical adenomatous hyperplasia, respectively.

The Efficacy of Internet-based Intervention on Quality of Life for Patients with Chronic Post-surgical Pain.

Background: The objective of the present study was to explore the efficacy of internet-based intervention on quality of life of patients with chronic post-surgical pain (CPSP).

Methods: A retrospective analysis was performed on 81 patients diagnosed with CPSP after radical resection for lung cancer between January 2013 and July 2014. They were enrolled either as part of the conventional care group which included 40 cases or the internet-based pain intervention group which included 41 cases.

Efficacy of whole-course pain intervention on health-related quality of life for patients after esophagectomy.

Purpose: The purpose of this study was to evaluate the efficacy of whole-course pain intervention on health-related quality of life (QoL) for patients after esophagectomy.

Methods: A retrospecitve analysis was performed on 81 patients who were enrolled as conventional care group (control group with 40 cases) and whole-course pain intervention group (observation group with 41 cases) respectively af?ter Sweet, Ivor-Lewis and McKeown esophagectomy between January 2011 and December 2013. Then, the postoperative recovery parameters of the patients were compared, accompanied with evaluation of QoL using the 36-Item Short Form Health Survey 6 months after the operation.

Recent perspectives of breast cancer prognosis and predictive factors.

Breast cancer is the most common type of cancer affecting women worldwide. Although there have been great improvements in treating the disease and at present between 80 and 90% of the women survive ≥5-years after their primary diagnosis. However, due to the high incidence of the disease >450,000 women succumb to breast cancer annually worldwide.

Staged bilateral single-port thoracoscopic lung volume reduction surgery: A report of 11 cases.

The aim of the present study was to investigate the feasibility and efficacy of staged bilateral single-port thoracoscopic lung volume reduction surgery (LVRS) for patients with chronic obstructive pulmonary emphysema (COPE). Eleven male patients with a mean age of 60.27±12.

Non-intubated simultaneous resection of pulmonary nodule and rib chondrosarcoma.

Adequate surgical resection was required for patients with rib chondrosarcoma. A 61-year-old woman was presented with a palpable chest wall mass. Computed tomography (CT) of the chest revealed an isolated pulmonary nodule about 0.

Non-intubated laparoscopic repair of giant Morgagni's hernia for a young man.

An asymptomatic patient was admitted as his chest photograph and computed tomography scans showed a giant Morgagni's hernia (MH). And it was repaired by laparoscopic approach under epidural anesthesia without endotracheal intubation. The hernia content of omentum was repositioned back into the abdominal cavity, and the diaphragmatic defect was repaired with composite mesh.