5 results match your criteria: "Xinjiang Clinical Research Center for precision medicine of digestive system tumor[Affiliation]"
Risk effects of environmental factors on human brucellosis in Aksu Prefecture, Xinjiang, China, 2014-2023.
Sci Rep
January 2025
School of Public Health, Xinjiang Medical University, Urumqi, China.
The context of rapid global environmental change underscores the pressing necessity to investigate the environmental factors and high-risk areas that contribute to the occurrence of brucellosis. In this study, a maximum entropy (MaxEnt) model was employed to analyze the factors influencing brucellosis in the Aksu Prefecture from 2014 to 2023. A distributed lag nonlinear model (DLNM) was employed to investigate the lagged effect of meteorological factors on the occurrence of brucellosis.
View Article and Find Full Text PDFEfficient and rapid auxiliary diagnosis of different grades of lung adenocarcinoma is conducive to helping doctors accelerate individualized diagnosis and treatment processes, thus improving patient prognosis. Currently, there is often a problem of large intra-class differences and small inter-class differences between pathological images of lung adenocarcinoma tissues under different grades. If attention mechanisms such as Coordinate Attention (CA) are directly used for lung adenocarcinoma grading tasks, it is prone to excessive compression of feature information and overlooking the issue of information dependency within the same dimension.
View Article and Find Full Text PDFCardiovascular safety of Janus kinase inhibitors in patients with rheumatoid arthritis: systematic review and network meta-analysis.
Front Pharmacol
August 2023
Department of Pharmacy, Karamay Central Hospital/Karamay Hospital of Xinjiang Uygur Autonomous Region People's Hospital, Karamay, China.
Article Synopsis
- Janus kinase (JAK) inhibitors are increasingly used to treat rheumatoid arthritis (RA), but their cardiovascular safety is still not fully established.
- A systematic review and meta-analysis of randomized controlled trials were conducted to compare cardiovascular risks associated with different JAK inhibitors in RA patients.
- The analysis of 14 selected trials involving 13,524 patients found no significant differences in major adverse cardiovascular events (MACE) compared to placebo, but indicated that JAK inhibitors showed higher all-cause mortality rates compared to adalimumab.
NEDD4L inhibits cell viability, cell cycle progression, and glutamine metabolism in esophageal squamous cell carcinoma via ubiquitination of c-Myc.
Acta Biochim Biophys Sin (Shanghai)
May 2022
Department of Hematologic and Oncology, Xinjiang Clinical Research Center for Precision Medicine of Digestive System Tumor, the Center Hospital of Karamay City, Karamay 834000, China.
Esophageal squamous cell carcinoma (ESCC) is a common subtype of esophageal cancer with high incidence. Surgery remains the main strategy for treatment of ESCC at early stage. However, the treatment outcome is unsatisfactory.
View Article and Find Full Text PDFUSP53 activated by H3K27 acetylation regulates cell viability, apoptosis and metabolism in esophageal carcinoma via the AMPK signaling pathway.
Carcinogenesis
May 2022
Department of General surgery, The Center Hospital of Karamay City, Xinjiang Clinical Research Center for precision medicine of digestive system tumor, Karamay, China.
Esophageal carcinoma (ESCA) is a leading cause of cancer death worldwide, despite an overall decline in the incidence of new cases. However, knowledge of gene expression signatures for risk and prognosis stratification of ESCA is inadequate. Thus, identifying novel molecular biomarkers and therapeutic targets for ESCA might improve its prognosis and treatment.
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