1 results match your criteria: "Xinhua Hospital Affiliated to Medicine School of Shanghai Jiaotong University Shanghai 200092[Affiliation]"
MiR-424 is over-expressed and attenuates ischemia-reperfusion kidney injury via p53 and death receptor 6 pathway.
Am J Transl Res
April 2019
Department of Nephrology, Xinhua Hospital Affiliated to Medicine School of Shanghai Jiaotong University Shanghai 200092, China.
Background: Ischemic reperfusion injury of kidney is major cause for renal failure, however the involved pathogenesis remains unclear creating an void for its effective treatment. Here we studied involvement of microRNA-424 in renal injury.
Methods: For the study, p53 or HIF-1α mice were used, ischemic renal injury was induced using clamping of renal pedicles bilateraly.