Prediction of miRNA-disease associations based on PCA and cascade forest.

Background: As a key non-coding RNA molecule, miRNA profoundly affects gene expression regulation and connects to the pathological processes of several kinds of human diseases. However, conventional experimental methods for validating miRNA-disease associations are laborious. Consequently, the development of efficient and reliable computational prediction models is crucial for the identification and validation of these associations.

Enhanced Degradation of Oxytetracycline Antibiotic Under Visible Light over BiWO Coupled with Carbon Quantum Dots Derived from Waste Biomass.

Improving the photogenerated carrier separation efficiency of individual semiconductor materials has always been a key challenge in photocatalysis. In this study, we synthesized a novel photocatalytic material, N-CQDs/UBWO, in situ by combining nitrogen-doped carbon quantum dots (N-CQDs) derived from discarded corn stover with ultrathin BiWO nanosheets (UBWO). Detailed characterization indicates that the random distribution of N-CQDs on the UBWO surface increases the specific surface area of UBWO, which is beneficial for the adsorption and degradation of oxytetracycline (OTC).

Effects of Different Concentrations of AmB on the Unsaturated Phospholipid-Cholesterol Membrane Using the Langmuir Monolayer and Liposome Models.

Amphotericin B (AmB) causes toxicity to the erythrocyte membrane, leading to hemolysis, which limits the clinically effective dose for AmB intravenous therapy in invasive fungal infections. The molecular mechanism by which AmB adheres to the membrane of erythrocytes is the key factor in causing AmB to be toxic to the membrane of erythrocytes, but it is not yet fully understood; the mechanism by which AmB adheres to the liquid microdomains with higher fluidity formed by cholesterol and unsaturated phospholipids remains especially unclear. This study examined the adsorption of AmB at different concentrations, 5, 45, 85, and 125 μg/mL, on unsaturated phospholipid membranes containing 50 mol% cholesterol.

ST-YOLO: A defect detection method for photovoltaic modules based on infrared thermal imaging and machine vision technology.

Photovoltaic panels are the core components of photovoltaic power generation systems, and their quality directly affects power generation efficiency and circuit safety. To address the shortcomings of existing photovoltaic defect detection technologies, such as high labor costs, large workloads, high sensor failure rates, low reliability, high false alarm rates, high network demands, and slow detection speeds of traditional algorithms, we propose an algorithm named ST-YOLO specifically for photovoltaic module defect detection. This algorithm is based on YOLOv8s.

Facile Synthesis of Fluorescent Carbon Quantum Dots with High Product Yield Using a Solid-Phase Strategy.

The liquid-phase method is the most commonly utilized strategy for synthesizing fluorescent carbon quantum dots (CQDs). However, the liquid-phase synthesis of CQDs faces challenges such as low yield, complex purification, and the use of toxic solvents, which limit large-scale production and practical applications. In this study, fluorescent CQDs with a high product yield of 78% were synthesized using glucose as a carbon source through a green and facile one-step solid-phase approach, without solvents or post-treatment.

RJ-TinyViT: an efficient vision transformer for red jujube defect classification.

Compared to the surface defect detection of industrial products produced according to specified processes, the detection of surface defects in naturally grown red jujubes poses unique and significant challenges for researchers. The high diversity of surface defects, subtle distinctions from the background, low contrast, varying scales, and the presence of high levels of noise in images are among the factors that greatly amplify the complexity of defect detection tasks. Existing methods show some deficiencies in addressing these issues, mainly due to insufficient feature extraction capabilities and overly complex network structures, leading to limitations in model efficiency and practical application performance.

Correction: Wang et al. CeO-Supported TiO-Pt Nanorod Composites as Efficient Catalysts for CO Oxidation. 2023, , 1867.

Following publication, concerns were raised regarding the peer-review process related to the publication of this article [...

NIDS-FGPA: A federated learning network intrusion detection algorithm based on secure aggregation of gradient similarity models.

With the rapid development of Industrial Internet of Things (IIoT), network security issues have become increasingly severe, making intrusion detection one of the key technologies for ensuring IIoT security. However, existing intrusion detection systems face challenges such as incomplete data features, missing labels, parameter leakage, and high communication overhead. To address these challenges, this paper proposes a federated learning-based intrusion detection algorithm (NIDS-FGPA) that utilizes gradient similarity model aggregation.

Lead-Free Hybrid Perovskite: An Efficient Room-Temperature Spin Generator via Large Interfacial Rashba Effect.

Two-dimensional (2D) hybrid organic-inorganic perovskite (HOIP) shows great potential for developing flexible and wearable spintronic devices by serving as spin sources via the bulk Rashba effect (BRE). However, the practical application of BRE in 2D HOIP faces huge challenges, particularly due to the toxicity of lead, which is crucial for achieving large spin-orbit coupling, and the restrictions in 2D HOIP candidates to meet specific symmetry-breaking requirements. To overcome these obstacles, we designed a strategy to exploit the interfacial Rashba effect (IRE) of lead-free 2D HOIP (CHCHCHNH)CuCl (PEA-CuCl), manifesting as an efficient spin generator at room temperature.

Synthesis, Crystal Structure and Antifungal Activity of ()-1-(4-Methylbenzylidene)-4-(3-Isopropylphenyl) Thiosemicarbazone: Quantum Chemical and Experimental Studies.

A novel ()-1-(4-methylbenzylidene)-4-(3-isopropylphenyl) thiosemicarbazone was synthesized in a one-pot four-step synthetic route. Fourier transform infrared spectroscopy (FTIR), H and C nuclear magnetic resonances (NMR), single-crystal X-ray diffraction, and UV-visible absorption spectroscopy were utilized to confirm the successful preparation of the title compound. Single-crystal data indicated that the intramolecular hydrogen bond N(3)-H(3)···N(1) and intermolecular hydrogen bond N(2)-H(2)···S(1) (1 - x, 1 - y, 1 - z) existed in the crystal structure and packing of the title compound.

SMLS-YOLO: an extremely lightweight pathological myopia instance segmentation method.

Pathological myopia is a major cause of blindness among people under 50 years old and can result in severe vision loss in extreme cases. Currently, its detection primarily relies on manual methods, which are slow and heavily dependent on the expertise of physicians, making them impractical for large-scale screening. To tackle these challenges, we propose SMLS-YOLO, an instance segmentation method based on YOLOv8n-seg.

Exploiting lignin-based nanomaterials for enhanced anticancer therapy: A comprehensive review and future direction.

Lignin, a renewable and abundant natural polymer, has emerged as a promising candidate for anticancer therapy due to its unique properties and biocompatibility. This review provides a comprehensive overview of recent advancements in the utilization of lignin-based nanomaterials for enhancing anticancer drug delivery and therapeutic outcomes. A detailed examination of the literature reveals several synthesis methods, including nanoprecipitation, microemulsion, and solvent exchange, which produce lignin nanoparticles with improved drug solubility and bioavailability.

Mechanical properties of aeolian sand cemented via microbially induced calcite precipitation (MICP).

The cementation of desert aeolian sand is a key method to control land desertification and dust storms, so an economical, green and durable process to reach the binding between sand grains needs to be searched. The method based on the microbially induced calcite precipitation (MICP) appeared in recent years as a promising process that proved its efficiency. The feasibility of the MICP technique to treat aeolian sand composed by low clay content, fine particles, low water content and characterized by weak permeability was demonstrated in the present paper.

Nitrogen plasma-induced phase engineering and titanium carbide/carbon nanotubes dual conductive skeletons endow molybdenum disulfide with significantly improved lithium storage performance.

MoS/TiC MXene composite has emerged as a promising anode material for lithium storage due to the synergistic combination of high specific capacity offered by MoS and conductive skeleton provided by TiC MXene. However, its two-dimensional/two-dimensional (2D/2D) structure is susceptible to collapse after long cycles, while the inherent low conductivity of MoS limits its rate performance. In this study, we developed a novel approach combining plasma-induced phase engineering with dual skeleton structure design to fabricate a unique P-MoS/TiC/CNTs anode material featuring highly conductive 1T phase MoS and a stable one-dimensional/two-dimensional (1D/2D) architecture.

A lightweight parallel attention residual network for tile defect recognition.

In modern industrial production, permanent magnet motors are an indispensable part of industrial manufacturing. The quality of the magnetic tiles directly affects the working performance of the permanent magnet motors, making the detection of defects on the surface of magnetic tiles critically important. However, due to the small size of defects on the tile image and the reflectivity of the defective surface, the details of image characteristics are not prominently acquired.

Exploratory research of intelligent gecko-inspired robot based on integrated design and experiment.

A quadruped robot with intelligent properties is developed using a bionics approach to explore the potential value of gecko-like machinery. The robot structure incorporates mechanical links, steering engines, and wheel groups, which can expand the movement function of its leg joint. A pneumatic control circuit that can generate negative pressure is built by a vacuum pump, electromagnetic valve, sucker, hose, and others, to enable mobile climbing and adsorption of the gecko-inspired robot.

Series of Fluorescent Dyes Derived from Triphenylamine Structure for Cu and In-Cell Carbon Monoxide Sensing: Synthesis and Performance.

In this paper, triphenylamine served as the structural core and was bonded to aromatic groups having various substituents [-OH, -OMe, or -N(Et)] by a =N-N= chain and then connected with aromatic groups having various substituents [-OH, -OMe, or -N(Et)]. The geometric and electronic properties of these probes were examined. It was found that the presence of electron donors enhanced the selectivity and emission quantum yield (QY).

Reverse Mode Polymer Stabilized Cholesteric Liquid Crystal Flexible Films with Excellent Bending Resistance.

The reverse-mode smart windows, which usually fabricated by polymer stabilized liquid crystal (PSLC), are more practical for scenarios where high transparency is a priority for most of the time. However, the polymer stabilized cholesteric liquid crystal (PSCLC) film exhibits poor spacing stability due to the mobility of CLC molecules during the bending deformation. In this work, a reverse-mode PSCLC flexible film with excellent bending resistance was fabricated by the construction of polymer spacer columns.

Superior Circularly Polarized Luminescence Brightness Achieved with Chiral Heteroleptic Nine-Coordinate Coumarin-Based Tb Complexes.

In order to facilitate the practical application of circularly polarized luminescence (CPL) active molecules, the CPL brightness () must be optimized. We have applied a binary modular strategy to synthesize two chiral organo-Tb complexes, [Tb(Coum)(1,2-Ph-PyBox)] () and [Tb(Coum)(1,2-Ph-PyBox)] (), combining 3-acetyl-4-hydroxy-coumarin () and enantiopure 2,6-bis(4-phenyl-2-oxazolin-2-yl) pyridine (,/,). The photophysical properties of these novel complexes have been fully characterized.