Association between vein diameters, reflux characteristics, and clinical severity in patients with chronic venous insufficiency in Northwest China.

Objective: Our goal was to summarize the relationship between vein diameters, reflux characteristics, and clinical severity in consecutive patients with chronic venous insufficiency (CVI) in Northwest China.

Methods: We evaluated 531 consecutive patients with CVI (249 women) who presented to the Department of Ultrasound of Xijing Hospital from September 2017 to July 2019. Reflux times and the mean diameters of the great saphenous, the small saphenous, and the calf perforator veins based on duplex ultrasound scans obtained in the standing position were recorded.

[Observation on therapeutic alliance with UDCA and glucocorticoids in AIH-PBC overlap syndrome].

Objective: To observe the efficacy of ursodeoxycholic acid (UDCA) combined with glucocorticoids in the treatment of autoimmune hepatitis-primary biliary cirrhosis (AIH-PBC) overlap syndrome.

Methods: 19 patients with AIH-PBC overlap syndrome were divided randomly into two groups: initiate combined group and initiate UDCA-monotherapy group. Biochemical responses and pathological features before and after treatment were analyzed retrospectively with student's t test, Wilcoxon rank sum test and Fisher's exact method.

[Comparison between two diagnostic criteria for PBC-AIH overlap syndrome].

Not Abstract.

Expression and significance of a new tumor suppression gene PTEN in primary renal cell carcinoma.

Background & Objective: PTEN gene is a newly discovered tumor suppressor gene, that maps to chromosome 10q23, and of longstanding interest to those studying somatic mutations in human tumors. Mutation and deletion of PTEN gene probably resulted in a new signal transduction pathway related to human malignant tumors. It was reported that PTEN gene mutated and deleted in renal cell carcinoma, however, there was no report concerning its expression in renal cell carcinoma.