2 results match your criteria: "Xiangshui County People's Hospital[Affiliation]"
MicroRNA-490-3p suppresses the proliferation and invasion of hepatocellular carcinoma cells via targeting TMOD3.
Oncol Lett
October 2020
Department of General Surgery, Xiangshui County People's Hospital, Yancheng, Jiangsu 224600, P.R. China.
Article Synopsis
- Hepatocellular carcinoma (HCC) is a primary liver cancer where microRNAs, particularly miR-490-3p, are believed to influence its progression.
- The study found that increasing miR-490-3p levels led to reduced cell growth, migration, and invasion in HCC cells (specifically Huh-7 and HEP 3B2.1-7) while promoting apoptosis by altering protein levels related to cell survival.
- The research also identified TMOD3 as a target of miR-490-3p, suggesting that this microRNA can inhibit HCC progression through its effects on TMOD3, pointing to a potential therapeutic avenue for treatment.
Morroniside protects against chronic atrophic gastritis in rat via inhibiting inflammation and apoptosis.
Am J Transl Res
September 2019
General Surgery, Xiangshui County People's Hospital Yancheng 224600, China.
The aim of our study was to investigate the therapeutic efficacy of Morroniside (MR) in a chronic atrophic gastritis (CAG) rat model and its underlying mechanisms. Male Wistar rats were employed to induce CAG model. All animals were divided into six groups: control, model (CAG), positive (Vitacoenzyme tablets), MR low, middle and high three doses groups.
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