Analysis of the Clinical Predictive Value of the Novel Inflammatory Indices SII, SIRI, MHR and NHR in Patients with Acute Myocardial Infarction and Their Extent of Coronary Artery Disease.

Background: This study aims to observe the relationship between novel inflammatory markers and AMI, and analyze its correlation with the degree of coronary artery disease.

Methods: Clinical data were collected from the control (510 cases) and AMI (406 cases) groups. The AMI group was classified into mild, moderate and severe according to the Gensini score.

Quantifying heavy metal and radionuclide contamination in fish and water proximal to a uranium tailings facility: A Linshui River basin investigation, China.

Background: The objective of this study is to evaluate the concentrations of heavy metals and radionuclides in water and fish samples collected from six designated sampling stations along the Linshui River, in close proximity to a Uranium Tailing Pond situated in China. Additionally, it seeks to estimate the bioaccumulation of heavy metals and conduct risk assessments, both carcinogenic and non-carcinogenic, for consumers.

Methods: Water and fish samples (yellowhead catfish and common carp) were systematically collected from six stations along the river from January to June 2023, adhering to ethical standards and standard protocols for assessing water quality.

WTAP participates in neuronal damage by protein translation of NLRP3 in an m6A-YTHDF1-dependent manner after traumatic brain injury.

Background: Traumatic brain injury (TBI) is a common complication of acute and severe neurosurgery. Remodeling of N6-methyladenosine (m6A) stabilization may be an attractive treatment option for neurological dysfunction after TBI. In the present study, the authors explored the epigenetic methylation of RNA-mediated NLRP3 inflammasome activation after TBI.

Inhibition of the ILK-AKT pathway by upregulation of PARVB contributes to the cochlear cell death in Fascin2 gene knockout mice.

The Fscn2 (Fascin2) gene encodes an actin cross-linking protein that is involved in the formation of hair cell stereocilia and retina structure. Mutations in Fscn2 gene have been linked to hearing impairment and retinal degeneration in humans and mice. To understand the function of the Fscn2 gene, we generated the Fscn2 knockout mice, which showed progressive loss of hearing and hair cells.

Pan-Cancer Analysis of the LOX Family Reveals that LOX Affects Tumor Prognosis by Affecting Immune Infiltration.

The lysyl oxidase (LOX) gene family encodes for a group of copper-dependent enzymes that play a crucial role in the cross-linking of collagen and elastin fibers in the extracellular matrix (ECM). Dysregulation of LOX gene expression has been implicated in various pathological conditions, including cancer. Several studies have shown that the LOX gene family is involved in cancer progression and metastasis.

A bibliometric analysis of global research trends of inflammation in cervical cancer: A review.

Cervical cancer is a common malignant tumor and a leading cause of death in women worldwide. It plays a crucial role in tumorigenesis and progression of cervical cancer. A total of 1606 references on inflammation in cervical cancer were retrieved from the Web of Science Core Collection and visual analysis was performed using VOSviewer.

Multiple forms of cell death: A focus on the PI3K/AKT pathway.

Cell death is a natural biological process that occurs in living organisms. Since 1963, extensive research has shed light on the occurrence, progress, and final outcome of cell death. According to different cell phenotypes, it is classified into different types, including apoptosis, pyroptosis, necroptosis, autophagy, ferroptosis, cuproptosis, and so on.

Social participation, psychological resilience and depression among widowed older adults in China.

Background: Depression has become a challenging public health problem, and the loss of a spouse is one of the main causes of depression in older adults. Social participation and psychological resilience are protective factors that reduce depressive symptoms in adults. The purpose of this study was to explore the influences of social participation and psychological resilience on the depression of Chinese widowed older adults.

-Nlrp3 is involved in the neuroprotection of phosphoglycerate mutase 5 deficiency in traumatic brain injury mice.

Introduction: Gut-microbiota-brain axis is a potential treatment to decrease the risk of chronic traumatic encephalopathy following traumatic brain injury (TBI). Phosphoglycerate mutase 5 (PGAM5), a mitochondrial serine/threonine protein phosphatase, resides in mitochondrial membrane and regulates mitochondrial homeostasis and metabolism. Mitochondria mediates intestinal barrier and gut microbiome.

Characterization and photocatalytic activity of CoCrO/g-CN nanocomposite for water treatment.

One of the materials that has recently been used to remove environmental pollution from industrial effluents with photocatalytic technology is cobalt chromate (CoCrO) nanoparticles. An effective way to improve the photocatalytic properties of materials is to composite them with other photocatalysts to prevent recombination of electron-holes and accelerate the transfer of oxidation/reduction agents. Graphitic carbon nitride (g-CN) is an excellent choice due to its unique properties.

Srs11-92, a ferrostatin-1 analog, improves oxidative stress and neuroinflammation via Nrf2 signal following cerebral ischemia/reperfusion injury.

Aim: Ferroptosis is increasingly becoming to be considered as an important mechanism of pathological cell death during stroke, and specific exogenous ferroptosis inhibitors have the ability to reverse cerebral ischemia/reperfusion injury. However, research on Srs11-92 (AA9), a ferrostatin-1 (Fer-1) analog, in preclinical studies is limited.

Methods: In the middle cerebral artery occlusion-reperfusion (MCAO/R) mice model or oxygen-glucose deprivation/reperfusion (OGD/R) cell model, Fer-1, AA9, and/or ML385 were administered, and brain infarct size, neurological deficits, neuronal damage, oxidative stress, and neuroinflammation were determined after the damage, in vitro and in vivo.

Evaluation of Human Settlement Environment and Identification of Development Barriers Based on the Ecological Niche Theory: A Case Study of Northern Shaanxi, China.

The quality of human settlement environment (HSE) is related to people's well-being. Since the implementation of the Western Development Strategy and the Grain to Green Program, the HSE in northern Shaanxi has undergone a major transformation. In order to explore the evolution pattern and seek a coordinated development strategy for all systems in the whole region, this paper, from the perspective of "production-living-ecological", evaluates the HSE niche breadth of northern Shaanxi based on the ecological niche theory, analyzes its spatial differentiation characteristics, and identifies the development barrier factors, with the help of ArcGIS spatial analysis tools and the barrier degree model.

The research frontier of cesarean section recovery: A bibliometric analysis.

Background: Cesarean section (CS) has become an effective means to solve dystocia and some obstetric complications, and to save the lives of women and perinatal women. Disparities in quality obstetric care and rehabilitation in CS result from differences in health care systems across regions, and more scientific and reasonable rehabilitation programmes and management measures will benefit more parturient and newborns worldwide who must take CS. In this study, we performed a bibliometric analysis to collect a graphical representation of the CS recovery.

The effect of Co-encapsulated GNPs-CNTs nanofillers on mechanical properties, degradation and antibacterial behavior of Mg-based composite.

Magnesium (Mg)-based composites, as one group of the biodegradable materials, enjoy high biodegradability, biocompatibility, and non-toxicity making them a great option for implant applications. In this paper, by the semi powder metallurgy (SPM) technique, the graphene nano-platelets (GNPs) and carbon nanotubes (CNTs) nanosystems, as reinforcements, are dispersed homogenously in the Mg-Zn (MZ) alloy matrix. Subsequently, the composite is successfully produced employing the spark plasma sintering (SPS) process.

The Effects of the Addition of Polyurethane-MgO Nanohybrids on the Mechanical Properties of Ordinary Portland Cement Paste.

One of the most important methods of controlling the properties of concrete and cement-based materials is to control the rate and kinetics of cement hydration. In the present study, novel flexible polyurethane-decorated MgO nanohybrids were synthesized using a simple chemical method, added to cement paste in different amounts, and utilized as an effective mechanical performance-enhancing factor for cement paste. It was observed that by adding 3 wt% synthesized PU-MgO nanohybrids to cement paste, its mechanical properties were improved and its compressive strength and flexural strength were increased by up to 13% and 15%, respectively, compared to the plain cement, after 45 days.

Microstructural Evolution during Accelerated Tensile Creep Test of ZK60/SiC Composite after KoBo Extrusion.

In the current study, the creep properties of magnesium alloy reinforced with SiC particles were investigated. For this purpose, ZK60/SiCp composite was produced by the stir casting method following the KoBo extrusion and precipitation hardening processes. The creep tests were performed at 150 °C under 10-110 MPa.

Analyzing Intention to Purchase Brand Extension via Brand Attribute Associations: The Mediating and Moderating Role of Emotional Consumer-Brand Relationship and Brand Commitment.

The aim of this study is to investigate the drivers of brand extension attributes and its impact on intention to purchase brand extensions mediated by emotional consumer-brand relationship (ECBR). Data was collected from Chinese university students with the help of questionnaire. Structure equation modeling was applied with the help of AMOS to analyze collected data.

The Effect of Eco-Friendly Inhibitors on the Corrosion Properties of Concrete Reinforcement in Harsh Environments.

In the present research, the synergistic effect of Arabic and guar gum inhibitors on the corrosion efficiency of concrete reinforcement was investigated. Thus, eight types of Arabic and guar gum combinations with 100, 250, 500, 750, and 1000 ppm were added to the steel reinforcement for 1, 7, 28, 48, and 72 days. The corrosion behavior of the samples was investigated by the electrochemical impedance (EIS) test.

Analyzing the Role of Corporate Social Responsibility for Sustainable Environmental Performance: Mediating Roles of Environmental Strategy and Environmental Outcomes.

This study examines the relationship between corporate social responsibility (CSR) and environmental performance, utilizing data from 415 small and medium-sized enterprises (SMEs) in China as a case study. We found that CSR has a direct and significant impact on environmental performance (EP) and is positively correlated to environmental strategy (ES) and environmental outcomes (EO), both of which improve environmental performance, i.e.

Effect of Heat Treatment Temperature on the Spinning Structure and Properties of a Cu-Sn Alloy.

A thin-walled copper (Cu)-tin (Sn) alloy cylinder was treated after spinning at 200-400°C for 0.5 h. The characteristics of the alloy microstructure under different temperatures were analyzed through electron back-scattered diffraction.

Sanbai Melon Seed Oil Exerts Its Protective Effects in a Diabetes Mellitus Model via the Akt/GSK-3/Nrf2 Pathway.

Traditional Chinese medicine (TCM) plays an important role in the treatment of type 2 diabetes mellitus (T2DM). However, the lack of adequate and scientifically rigorous evidence has limited its application in this disorder. Sanbai melon seed oil (SMSO) is used in folk medicine to treat DM; however, only few literature reports exist regarding its mechanism.

Decolorization effect and related mechanism of atmospheric pressure plasma jet on Eriochrome Black T.

In this study, Eriochrome Black T (EBT) in water was decolorized by means of argon atmospheric pressure plasma jet (APPJ), which showed great decolorization performance. The results showed that the relatively high decolorization rate (approximately 80%) was obtained after plasma treatment for 6 min. Changes to some reactive oxygen and nitrogen species (RONS) in the liquid phase were detected.