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Article Synopsis
  • The study investigates the effectiveness of novel negative pressure ureteroscopic lithotripsy (NP-URL) combined with flexible ureteroscopy (FU) compared to percutaneous nephrolithotomy (PCNL) in treating kidney stones.
  • A cohort of 166 participants with 2-4 cm kidney stones was analyzed, showing NP-URL-FU had an 86% lower stone-free rate (7 days) than PCNL, but no significant differences for the 2-month stone-free rate.
  • The findings suggest NP-URL-FU may be a suitable alternative for patients wanting a less invasive surgical option, despite its immediate effectiveness being lower than PCNL.
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