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FOXN3 Regulates Autophagic Activity to Suppress Drug Resistance in Melanoma Cells.

Clin Cosmet Investig Dermatol

November 2024

Department of Dermatology, Xi'an Jiaotong University The Second Affiliated Hospital, Xi'an, Shaanxi, People's Republic of China.

Background: The forkhead box (FOX) family member FOXN3 has been reported to inhibit transcriptional activity associated with regulating tumor development. However, the role of FOXN3 in the pathogenesis of melanoma is not well understood.

Objective: To investigate the biological functions of FOXN3 in drug resistance of melanoma.

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