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The critical roles of lnc-GLYATL2-2/PD-L1 axis in immune microenvironment and the clinical value of intracranial chordomas.
Am J Cancer Res
December 2023
Hospital for Chronic Neurological Diseases, Xi'an International Meidical Center Hospital Affiliated to Northwest University Xi'an 710000, Shaanxi, China.
Intracranial chordomas (ICs) are associated with a poor prognosis due to low total resection rates and high recurrence rates. However, the role of immunotherapy in ICs remains unknown. RNA sequencing and immunohistochemical staining were performed on IC tissues and normal tissues, and the long noncoding RNA (lncRNA) lnc-GLYATL2-2 was identified.
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