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Abnormal percent amplitude of fluctuation in patients with lifelong premature ejaculation is associated with neurotransmitter profiles.
Brain Imaging Behav
October 2024
Department of Urology, Xi'an Daxing Hospital Affiliated to Medical College of Yan'an University, Xi'an, 710071, Shaanxi, China.
Article Synopsis
- Identifying new imaging biomarkers for lifelong premature ejaculation (LPE) could help us understand the brain processes behind this condition.
- In a study involving 46 LPE patients and 35 healthy controls, researchers used a technique called Percent Amplitude of Fluctuation (PerAF) to compare brain function during rest, finding notable differences between the two groups.
- Results showed increased PerAF in areas linked to emotional and sensory processing in LPE patients, along with correlations between PerAF changes and neurotransmitter systems, suggesting that ejaculatory control issues may stem from neurotransmitter dysregulation.