Correction: A study on a telo21 G-quadruplex DNA specific binding ligand: enhancing the molecular recognition ability the amino group interactions.

[This corrects the article DOI: 10.1039/C8RA03833C.].

A study on a telo21 G-quadruplex DNA specific binding ligand: enhancing the molecular recognition ability the amino group interactions.

A symmetric ligand is synthesized composed of a core -methylpyridinium scaffold and two -substituted benzyl groups through a flexible ethylene bridge to form a novel three-ring-conjugated system. The ligand system was found to have only weak background fluorescent signal in aqueous or physiological conditions and exhibited strong fluorescent signal enhancement targeting at telo21 G-quadruplex structure rather than other types of nucleic acids. The comparison study with two terminal groups (-N(CH) -SCH) indicates that the stimulated signal enhancement of specific binding is probably attributed to the hydrogen-bonding interactions through the amino groups in the G-quartets.