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Netrin-1 alleviates subarachnoid haemorrhage-induced brain injury via the PPARγ/NF-KB signalling pathway.
J Cell Mol Med
March 2019
Department of Neurosurgery, Wuxi Medical College of Anhui Medical University (l0lst Hospital of PLA), Wuxi City, Jiangsu Province, PR. China.
Netrin-1 (NTN-1) is a novel drug to alleviate early brain injury following subarachnoid haemorrhage (SAH). However the molecular mechanism of NTN-1-mediated protection against early brain injury following SAH remains largely elusive. This study aims to evaluate the effects and mechanisms of NTN-1 in protecting SAH-induced early brain injury.
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