2 results match your criteria: "Wuhan University of Science and Technology Affiliated Puren Hospital[Affiliation]"
Icariside II Alleviates Chondrocyte Inflammatory Injury by Inhibiting the TNIP2/NF-κB Pathway.
Cell Biochem Biophys
January 2025
Department of Pain Medicine, Wuhan University of Science and Technology Affiliated Puren Hospital, Wuhan, China.
Icariside II exerts protective effects against various diseases; however, its specific effects on osteoarthritis (OA) remain unclear. Therefore, in this study, we aimed to investigate the effects of icariside II in an in vitro model of OA and analyze its action mechanisms. We established an in vitro OA model by treating a human chondrocyte cell line (CHON-001) with interleukin (IL)-1β, followed by treatment with different concentrations of icariside II.
View Article and Find Full Text PDFlncRNA BZRAP1-AS1 alleviates rheumatoid arthritis by regulating miR-1286/COL5A2 axis.
Immun Inflamm Dis
February 2022
Department of Pain Medicine, Wuhan University of Science and Technology Affiliated Puren Hospital, Wuhan, Hubei, China.
Background: Dysregulation of BZRAP1-AS1 was associated with immune statuses of cancer or Alzheimer's disease patients, yet little is known about its role in rheumatoid arthritis.
Methods: RT-qPCR and western blot were applied to assess the expression of indicated expression. CCK-8 and BrdU proliferation assays were used to measure the proliferation of RA-HFLS.