437 results match your criteria: "Wuhan Sports University[Affiliation]"

Mental fatigue is an important factor affecting athletes' performance. Explaining the effects of mental fatigue on sports performance from a theoretical point of view can help us deeply understand the interconnection between mental fatigue and sports performance and conduct effective interventions based on this. Combining the relevant literature in China and abroad reveals that the current academic theories on the mechanism of sports fatigue include motivational control theory, underload theory, neural waste disposal hypothesis, and resource depletion theory.

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Circ-PDE1C/miR-766-3p/SGTB axis regulates the IL-1β-induced apoptosis, inflammation and oxidative stress in human chondrocytes.

Adv Rheumatol

December 2024

Department of Rehabilitation Medicine, Wuhan No.1 Hospital, 215 Zhongshan Avenue, Qiaokou District, Wuhan, Hubei, 430022, China.

Background: Osteoarthritis (OA) is a common degenerative joint disease. Circular RNA Phosphodiesterase 1 C (circ-PDE1C, hsa_circ_0134111) has participated in the IL-1β-induced chondrocyte damages. The objective of our study was to explore the molecular mechanism of circ-PDE1C.

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Background: Differentiating between traumatic and non-traumatic spinal cord injuries (NT-SCI) is critical, as these classifications may significantly impact patients' health outcomes and overall well-being, potentially resulting in differences in treatment protocols and therapeutic efficacy.

Objective: This study aims to compare the quality of life (QoL) and satisfaction with life (SWL) among individuals with traumatic spinal cord injuries (T-SCI), NT-SCI, and the healthy population in China.

Method: A quantitative, cross-sectional survey was conducted between July and December 2020 in the Rehabilitation and Physiotherapy Department of Tongji Hospital, Hubei University of Science and Technology.

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Musculoskeletal disorders are a series of diseases involving bone, muscle, cartilage, and tendon, mainly caused by chronic strain, degenerative changes, and structural damage due to trauma. The disorders limit the function of patients due to pain and significantly reduce their quality of life. In recent years, adipose-derived mesenchymal stem cells have been extensively applied in regeneration medicine research due to their particular abilities of self-renewal, differentiation, and targeted homing and are more easily accessed compared with other sources.

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Mesenchymal stem cell-derived extracellular vesicles: A promising therapeutic strategy in diabetic osteoporosis.

World J Diabetes

December 2024

Preventive Treatment of Acupuncture and Moxibustion of Hubei Provincial Collaborative Innovation Center, College of Acupuncture-Moxibustion and Orthopaedics of Hubei University of Chinese Medicine, Wuhan 430065, Hubei Province, China.

Diabetic osteoporosis (DOP) is a serious complication of diabetes mellitus. It is urgent to explore efficient clinical treatment strategies for DOP. It has been found that mesenchymal stem cell-derived extracellular vesicles (MSC-EVs), as an emerging cell-free therapy, show great potential in DOP treatment.

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Highly sensitive electrochemical Osteoprotegerin (OPG) immunosensor for assessing fracture healing and evaluating drug efficacy.

Bioelectrochemistry

December 2024

Hubei Province Key Laboratory of Occupational Hazard Identification and Control, School of Public Health, Faculty of Medicine, Wuhan University of Science and Technology, Wuhan 430065, PR China. Electronic address:

Article Synopsis
  • Tibial fractures are common injuries and require careful monitoring for proper healing, with Osteoprotegerin (OPG) being a crucial marker for this process.
  • A new, highly sensitive electrochemical immunosensor has been developed using a nanocomposite material that enhances detection of OPG in serum, addressing existing methods' limitations in sensitivity and specificity.
  • This immunosensor shows excellent performance in terms of specificity and stability and is validated for clinical use, effectively aiding in the assessment of fracture healing and the evaluation of orthopedic drug efficacy in real patient samples.
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Exercise alleviates cognitive decline of natural aging rats by upregulating Notch-mediated autophagy signaling.

Brain Res

December 2024

College of Sports Medicine, Wuhan Sports University, Wuhan 430079, China; Hubei Key Laboratory of Exercise Training and Monitoring, Wuhan 430079, China. Electronic address:

Notch signaling, a classical signaling pathway of neurogenesis, is downregulated during the aging and age-related neurodegenerative diseases. Exercise has been proposed as an effective lifestyle intervention for delaying cognitive decline. However, it remains unclear whether exercise intervention could alleviate cognitive decline by modulating neurogenesis in naturally aging rats.

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Neural dynamics underlying coordination between training-induced habitual and goal-directed responses.

Cogn Affect Behav Neurosci

December 2024

Department of Psychological & Brain Sciences, Boston University, Boston, MA, USA.

Article Synopsis
  • * Well-trained athletes, with their automatic reactions to sports-related cues, were used in a study where EEG was recorded as they completed a Simon task involving these expertise-related stimuli.
  • * Results showed athletes had a stronger response to these expert stimuli compared to neutral ones, indicating better coordination and response inhibition linked to their training, which is reflected in their brain activity during the task.
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ZS09 Can Improve Antibiotic-Induced Motor Dysfunction in Mice by Regulating the Brain-Gut Functions.

J Inflamm Res

November 2024

Collaborative Innovation Center for Child Nutrition and Health Development, Chongqing University of Education, Chongqing, 400067, People's Republic of China.

Purpose: When consumed in appropriate quantities, probiotics, which are live microorganisms, are good for health. In this study, a mouse model of antibiotic-induced dyskinesia was established using a sterile mixed antibiotic solution to investigate the preventive impact of ZS09 (LFZS09) on this condition in mice.

Methods: Following modeling, alterations in the serum and brain tissue of mice were assessed for motor measures such as running and swimming, malondialdehyde (MDA), superoxide dismutase, reduced glutathione, interleukin (IL-6, IL-10), and tumor necrosis factor (TNF)-α.

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The effect of aerobic exercise on sleep disorder in menopausal women: a systematic review and meta-analyses.

BMC Womens Health

December 2024

China Youth Sports and the Integration of Sports and Education Public Policy Research Center, Wuhan Sports University, Wuhan, 430079, Hubei, China.

Objective: This study systematically evaluated the effect of aerobic exercise on sleep disorders in menopausal women and proposed a practical program from the perspective of "what to practice," "how much to practice," and "how to practice." We proposed the program from the standpoint of training science.

Methods: Up to March 20, 2023, a total of 16 articles and 19 RCT studies were retrieved from Web of Science, PubMed, Springer, Science Direct, China Knowledge Network, Wanfang, and VIP.

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Associations of physical activity, screen time, sleep duration with optimal eating habits among adolescents.

Complement Ther Clin Pract

November 2024

School of Physical Education, Wuhan Sports University, Wuhan, China. Electronic address:

Objective: The aim of this study was to explore the associations of physical activity, screen time and sleep duration with various eating habits among children.

Methods: The data were collected from six surveys of the Youth Risk Behaviour Survey conducted in 2011, 2013, 2015, 2017, 2019, and 2021, with a total of 78, 697 participants with complete information. Information on demographic characteristics (e.

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Risk factors for secondary vertebral compression fracture after percutaneous vertebral augmentation: a single-centre retrospective study.

J Orthop Surg Res

November 2024

Department of Minimally Invasive Spinal Surgery, The Affiliated Hospital of Wuhan Sports University, NO 279 Luoyu Road, Hongshan District, Wuhan, 430079, Hubei, China.

Article Synopsis
  • The study aimed to assess the occurrence of secondary vertebral compression fractures (SVCF) after percutaneous vertebral augmentation (PVA) and to identify associated risk factors for better clinical guidance.
  • A retrospective analysis involved 288 PVA cases, categorizing patients into groups based on whether they experienced SVCF during follow-up, while collecting various health and procedural data.
  • Results showed a 14.60% incidence of SVCF, with significant risk factors identified, including age, body mass index, fat infiltration in muscles, cement leakage, and procedural techniques, evaluated through statistical analyses.
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Article Synopsis
  • Chronic syndesmotic instability (CSI) can lead to significant long-term pain and disability, and this study explored factors contributing to its development in patients with unresolved acute ankle sprains.
  • Researchers analyzed data from 356 patients who underwent ankle arthroscopy and identified 5 main clinical risk factors linked to CSI: deltoid ligament injuries, a positive bandage-binding test, moderate to severe injury of the posterior inferior tibiofibular ligament, a positive squeeze test, and higher body mass index (BMI).
  • The findings suggest that recognizing these risk factors can help in managing and possibly preventing CSI after initial ankle sprain treatments.
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An empirical study on smart city construction to enhance residents' participation in physical activity.

Sci Rep

November 2024

Martial Arts Academy, Wuhan Sports University, No. 461 Luoyu Rd., Hongshan District, Wuhan, 430079, Hubei Province, China.

Smart city construction, as a new model of urban development, has become a crucial means to encourage residents' participation in physical exercise. However, there is still a lack of systematic exploration regarding the mechanisms by which smart city construction specifically affects residents' engagement in physical activity. This paper analyzes the impact of smart city construction on residents' participation in physical activity using a Difference-in-Differences (DID) model, based on data from the 2010 to 2020 China Family Panel Studies (CFPS).

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Purpose: Manual wheelchair users with spinal cord injury (SCI) face challenges in wheelchair skill training (WSTr) due to the complexity of learning advanced skills and limited access to rehabilitation services. This review aims to summarize existing WSTr methods for individuals with SCI/disabilities and propose the use of Augmented Reality (AR)-enhanced Immediate Visual Feedback (ARe-IVF) learning modules for wheelie and curbing skill training.

Methods: The proposed ARe-IVF learning modules will incorporate AR-enhanced visual feedback, allowing users to visualize spatial and temporal aspects of wheelchair skills and assess their performance through computer vision technology.

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Objective: This study aims to systematically evaluate the burden of low back pain(LBP) in the middle-aged population across global regions and between genders, assess the major risk factors and their impacts, and project the burden to 2050, providing a scientific basis for global preventive actions.

Methods: This study utilized The Global Burden of Disease(GBD) 2021 database. First, we integrated the population data of the 45-49, 50-54, and 55-59 age groups provided by the GBD using a weighted average method to calculate the Disability-adjusted life years(DALYs) rate for the middle-aged population aged 45 to 59 years.

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Objective: To investigate the neuromuscular activity characteristics of Tai Chi athletes and identify optimal muscle synergy patterns.

Method: Data were collected from 12 elite Tai Chi athletes using a Vicon motion capture system, a Kistler 3D force plate, and a Noraxon surface electromyography system. Muscle synergy patterns were extracted using Non-negative Matrix Factorization.

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Background: The causal relationships between amyotrophic lateral sclerosis (ALS), Parkinson disease and different intensities of physical activity (PA) are still inconclusive. To evaluate the causal impact of PA on ALS and Parkinson disease (PD), this study integrates evidence from Mendelian randomization (MR) using a meta-analysis approach.

Methods: MR analyses on genetically predicted levels of PA (compose of self-reported moderate-to-vigorous physical activity [MVPA], self-reported vigorous physical activity [VPA], and strenuous sports or other exercises [SSOE]) regarding ALS and PD published up to July 27, 2024, were obtained from PubMed, Scopus, Web of Science, and Embase.

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Oriental covalent immobilization of N-glycan binding protein via N-terminal selective modification.

Anal Chim Acta

November 2024

Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China. Electronic address:

Lectin affinity chromatography is one of powerful tools for the study of protein glycosylation. Different lectin proteins can recognize different structures of monosaccharides or oligosaccharide units, allowing for the selective separation of glycopeptides or glycoproteins containing different polysaccharide structures. However, the N-glycans were only partially captured by most of common lectins, reducing the coverage rate of identifying N-glycoconjugates.

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Exerkine irisin mitigates cognitive impairment by suppressing gut-brain axis-mediated inflammation.

J Adv Res

October 2024

Tianjiu Research and Development Center for Exercise Nutrition and Foods, Hubei Key Laboratory of Exercise Training and Monitoring, College of Sports Medicine, Wuhan Sports University, Wuhan 430079, China. Electronic address:

Article Synopsis
  • * After 12 weeks of aerobic exercise and irisin injections, results showed that cognitive decline in aged mice was reversed, with notable changes in metabolites and gene expression linked to inflammation.
  • * Findings suggest that aging-related cognitive impairment is connected to insulin resistance and specific signaling pathways, indicating that irisin may help optimize gut health and metabolism during exercise.
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Purpose: This study examined the impacts of customer knowledge management and flow experience on customer value co-creation and the mediating role of flow experience in the context of fitness apps.

Design/methodology/approach: Using the questionnaire star platform to edit the questionnaire and collect data(n = 450). A structural equation modeling test was conducted to examine the relationships between the variables.

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The study aimed to explore the effect and mechanism of resistance exercise (RE) on cognitive dysfunction in type 2 diabetes mellitus (T2DM) mice. Six 8-week-old male m/m mice were used as control (Con) group, and db/db mice of the matched age were randomly divided into model control (db/db) group and db+RE group, with 6 mice in each group. The db+RE group was given 8 weeks of resistance climbing ladder exercise intervention.

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Excellent properties of NaF and NaBr induced DNA/gold nanoparticle conjugation system: Better stability, shorter modified time, and higher loading capacity.

Biosens Bioelectron

January 2025

Britton Chance Center for Biomedical Photonics at Wuhan National Laboratory for Optoelectronics─Hubei Bioinformatics & Molecular Imaging Key Laboratory, Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, Hubei, China; Key Laboratory of Biomedical Photonics (HUST), Ministry of Education, Huazhong University of Science and Technology, Wuhan, 430074, Hubei, China. Electronic address:

The functionalization of gold nanoparticle (AuNP) is the key procedure for the biochemical and biomedical application. The conventional salt-aging method requires the stepwise additions of NaCl and excessive thiolated DNA, mainly due to the poor tolerance of the DNA/AuNP mixture toward NaCl. Herein, we found that NaF is capable of improving the stability for the modification of AuNP with different bases of DNA sequences (poly A/T/C/G), and allows for adding up with a high concentration of 200 mM at one time, which greatly reduces the total modification time to 0.

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Correlation between the biomechanical characteristics and stability of the 143D movement during the balance phase in competitive Tai Chi.

Front Bioeng Biotechnol

October 2024

Engineering Research Center of Sports Health Intelligent Equipment of Hubei Province, Wuhan Sports University, Wuhan, China.

Objective: To explore the biomechanical factors affecting the stability of athletes in the 143D balance phase of competitive Tai Chi.

Method: The Vicon 3D motion capture system, Kistler 3D force platform, and Noraxon surface electromyography (sEMG) system were used to measure the joint angle, joint moment, center of gravity, ground reaction force, and sEMG data of athletes. The stability index was then calculated according to the formula.

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