Conference 2024: Building an innovative scientific research ecosystem for microbiome and One Health.

The Conference 2024 provides a platform to promote the development of an innovative scientific research ecosystem for microbiome and One Health. The four key components - Technology, Research (Biology), Academic journals, and Social media - form a synergistic ecosystem. Advanced technologies drive biological research, which generates novel insights that are disseminated through academic journals.

Nicotinamide mononucleotide protects STAT1 from oxidative stress-induced degradation to prevent colorectal tumorigenesis.

Colitis, accompanied by the accumulation of reactive oxygen species (ROS) in the intestinal tract, is a risk factor for colorectal cancer (CRC). Our previous studies indicate that nicotinamide mononucleotide (NMN) replenishment reduces chronic inflammation. In this study, we confirm that NMN supplementation reduces inflammatory cytokine levels and oxidative tissue damage in an azoxymethane/dextran sulfate sodium (AOM/DSS)-induced colitis-associated cancer (CAC) model.

An optimized heating source for heat-not-burn tobacco products through synergistic combustion of tobacco stalk and graphite carbon with KCO catalyst.

Waste tobacco stalk is blended with graphite carbon to form a composite carbon source, which is a promising external heating system for heat-not-burn tobaccos. In the current work, the effects of tobacco stalk amounts and the catalyst KCO on the co-combustion characteristics (, the ignition temperature, burnout temperature, ) of graphite carbon were investigated. As a result, the ignition temperatures of the blend were determined by the tobacco straw, while the burnout temperature of the samples was reduced by approximately 60 °C due to the addition of a tobacco stalk.

ImageGP 2 for enhanced data visualization and reproducible analysis in biomedical research.

ImageGP is an extensively utilized, open-access platform for online data visualization and analysis. Over the past 7 years, it has catered to more than 700,000 usages globally, garnering substantial user feedback. The updated version, ImageGP 2 (available at https://www.

Composite hydrogels based on deep eutectic solvents and lysine for pressure sensors and adsorption of Fe.

This study explored the preparation of a novel composite hydrogel based on deep eutectic solvent (DES) with lysine (Lys) and its application in pressure sensing and Fe adsorption. DES was synthesized from acrylamide (AM) and urea (U) as hydrogen bond donors (HBD) with choline chloride (ChCl) as hydrogen bond acceptor (HBA), and Lys was used as a functional filler, and Lys/P(AM-U-ChCl) composite hydrogels were successfully prepared by frontal polymerization (FP) method. The structure of the hydrogels was characterized in depth using Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM).

Enhanced photocatalytic CO conversion of a CdS/Co-BDC nanocomposite Co(ii)/Co(iii) redox cycling.

Photocatalytic CO reduction into value-added chemical fuels using sunlight as the energy input has been a thorny, challenging and long-term project in the environment/energy fields because of to its low efficiency. Herein, a series of CdS/Co-BDC composite photocatalysts were constructed by incorporating CdS nanoparticles into Co-BDC using a dual-solvent growth strategy for improving photocatalytic CO reduction efficiency. The composites were characterized through XRD, SEM, TEM, XPS, DRS and EPR techniques in detail.

ChatGPT and generative AI are revolutionizing the scientific community: A Janus-faced conundrum.

The advent of generative artificial intelligence (AI) technologies marks a transformative moment for the scientific sphere, unlocking novel avenues to elevate scientific writing's efficiency and quality, expedite insight discovery, and enhance code development processes. Essential to leveraging these advancements is prompt engineering, a method that enhances AI interaction efficiency and quality. Despite its benefits, effective application requires blending researchers' expertise with AI, avoiding overreliance.

Structure-activity relationship study of anti-wear additives in rapeseed oil based on machine learning and logistic regression.

Anti-wear performance is a crucial quality of lubricants, and it is important to conduct research into the structure-activity relationship of anti-wear additives in bio-based lubricants. These lubricants are eco-friendly and energy-efficient. A literature review resulted in the construction of a dataset comprising 779 anti-wear properties of 79 anti-wear additives in rapeseed oil, at various loadings and additive levels.

Preparation of anisotropic polyimide aerogels for thermal protection with outstanding flexible resilience using the freeze-drying method.

Polyimide aerogels (PIAs) not only possess excellent thermodynamic properties but also have a high porosity structure, making them an exceptional protective and thermal insulation material, and further broadening their application scope in aerospace and other cutting-edge fields. In this work, a series of anisotropic polyimide aerogels (3,3',4,4'-biphenyltetracarboxylic dianhydride (S-BPDA), -phenylenediamine (PDA), 4,4'-diaminodiphenyl ether (ODA)) with excellent properties were prepared. These PIAs were obtained by unidirectional freeze-drying and thermal amination of two different precursor solutions mixed in proportion.

Enhanced Fe(ii)/Fe(iii) cycle by boron enabled efficient Cr(vi) removal with microscale zero-valent iron.

Recently, researchers have been paying much attention to zero-valent iron (ZVI) in the field of pollution remediation. However, the depressed electron transport from the iron reservoir to the iron oxide shell limited the wide application of ZVI. This study was aimed at promoting the performance of microscale ZVI (mZVI) for hexavalent chromium (Cr(vi)) removal by accelerating iron cycle with the addition of boron powder.

Influence of oxygen content on selective laser melting leading to the formation of spheroidization in additive manufacturing technology.

Selective laser melting (SLM) additive manufacturing technology with different oxygen contents leads to the appearance of spherical solids of different sizes on the surface of the part, which affects the mechanical properties of the part, surface roughness, In this study, the SLM molding technique was applied using three different 316L metal powders with different oxygen contents. The spheroidization properties and morphology of the samples were observed using a Quanta 200 environmental scanning electron microscope (ESEM), and the samples were observed microscopically and subjected to EDX spectroscopy using metallographic microscopy, and the mechanical properties were investigated. The results of the study showed that when using gas atomized powders, no spheroidization occurred when the oxygen content of the powders was 5.

Preparation of PEG/P(U-AM-ChCl) composite hydrogels using ternary DES light polymerization and their properties.

Deep eutectic solvents (DES) were prepared using urea (U) and acrylamide (AM) as hydrogen bond donors (HBD) and choline chloride (ChCl) as hydrogen bond acceptor (HBA), and polyethylene glycol (PEG) was selected as a filler and uniformly dispersed in DES to prepare PEG/P(U-AM-ChCl) composite hydrogels by light polymerization. The composite hydrogels were characterized by scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR). The effects of the content of PEG on the swelling properties, mechanical properties and fatigue resistance of the composite hydrogels were investigated.

Research and application of surface heat treatment for CO continuous laser ablation of polymeric methyl methacrylate materials.

Based on the influence of a filamentous laser Gaussian heat source and its movement speed on Polymeric Methyl Methacrylate materials (PMMA sheets), the physical model of heat transfer of PMMA materials by CO continuous laser ablation was established. Numerical simulation research on heat transfer in CO continuous laser processing of PMMA sheets was carried out by applying the heat transfer model, and experiments on continuous laser processing of PMMA sheets were conducted on the basis of the numerical simulation results. Theoretical and experimental research indicated that under relevant conditions, when the laser power was 20 W, the maximum surface temperature of PMMA sheet was approximately 520 K, which was higher than the melting temperature of the PMMA material, achieving the transformation of the PMMA material from solid to liquid phase in the laser ablation area.

Insect multimeric G-quadruplexes fold into antiparallel structures of different compactness and stability in K and Na solutions.

Human telomere sequences (TTAGGG) fold into G-quadruplexes with different conformations in K and Na solutions, which are highlighted for their potential as antitumor drug targets. Moreover, human multimeric G-quadruplexes have been broadly studied potentially for screening ligands with higher selectivity than monomeric G-quadruplexes. Most insects have telomeres consisting of pentanucleotide (TTAGG) repeats, which fold into an antiparallel structured G-quadruplex with a two-layer G-planar in a K solution.

Facile fabrication of CoAl-LDH nanosheets for efficient rhodamine B degradation peroxymonosulfate activation.

Layered double hydroxides (LDHs) have been extensively investigated as promising peroxymonosulfate (PMS) activators for the degradation of organic pollutants. However, bulk LDHs synthesized using conventional methods possess a closely stacked layered structure, which seriously blocks active sites and yields low intrinsic activity. In this study, we exfoliated bulk CoAl-LDHs to fabricate CoAl-LDH nanosheets by alkali-etching and Ostwald ripening a simple hydrothermal process in a KOH solution.

Pd nanoparticles decorated ultrathin 2D metal-organic framework nanosheets with enhanced peroxidase-mimic activity and colorimetric assay of glucose.

In addition to size, shape and morphology, enzyme-mimetic property could be efficiently regulated by controlling composition, forming complexes or hybrids, and surface modification. Herein, Pd nanoparticles with an average diameter of 2.52 nm were decorated on ultrathin 2D copper(ii)-porphyrin derived metal-organic framework (MOF) nanosheets by a simple reduction method for catalytic activity regulation.

Preparation and characterization of PA/P(AA--AM) composite hydrogels photopolymerization.

The present study synthesized a deep eutectic solvent (DES) using acrylic acid (AA), acrylamide (AM), and choline chloride (ChCl), and added phytic acid (PA) as a filler. Subsequently, the PA/P(AA--AM) composite hydrogel was prepared under ultraviolet irradiation and used a photoinitiator. Characterization of the hydrogels was conducted using Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM).

Preparation of SA/P(U-AM-ChCl) composite hydrogels by frontal polymerization and its performance study.

Deep eutectic solvent (DES) was synthesized from urea (U), acrylamide (AM) and choline chloride (ChCl), sodium alginate (SA) was selected as filler, and SA/P(U-AM-ChCl) composite hydrogel was prepared by thermal initiation frontal polymerization (FP). The hydrogels were characterised by Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). The effects of SA on the swelling properties, mechanical properties and self-healing properties of the composite hydrogels were investigated.

Preparation of novel β-CD/P(AA--AM) hydrogels by frontal polymerization.

In this paper, betaine (Bet) was used as a hydrogen bond acceptor (HBA), and acrylic acid (AA) and acrylamide (AM) were used as hydrogen bond donors (HBD) and mixed to form a deep eutectic solvent (DES). Different concentrations of β-cyclodextrin (β-CD) were dispersed in the DES, and a novel β-CD/P(AA--AM) hydrogel was prepared by frontal polymerization (FP). The characteristic structure and morphology of the hydrogels were analyzed using Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM), and the properties of the hydrogels were investigated.

Preparation and properties of CS/P(AM--AA) composite hydrogels by frontal polymerization of ternary DES.

A deep eutectic solvent (DES) was prepared from choline chloride (ChCl), acrylamide (AM) and acrylic acid (AA); chitosan (CS) was used as a filler, and CS/P(AM--AA) composite hydrogels were prepared by frontal polymerization (FP). The hydrogels were characterized by Fourier transform infrared spectroscopy (FTIR) and scanning electron microscopy (SEM). The mechanical properties, pH responsiveness and conductivity of the hydrogel were studied.

RHPS4 shifted the conformation ensemble equilibrium of Tel24 by preferentially stabilizing the (3 + 1) hybrid-2 conformation.

Telomeric G-quadruplexes have been a promising target for developing antitumor drugs with fewer side effects. The intracellular environment is usually in a state of molecular crowding. Studying the interaction mechanism among ligands and telomeric G-quadruplexes under crowded conditions is important for designing drugs that target telomeric G-quadruplexes.

2D TiVCT layered nanosheets grown on nickel foam as highly efficient electrocatalysts for the hydrogen evolution reaction.

Exploring highly efficient and durable catalysts for the hydrogen evolution reaction (HER) is crucial for the hydrogen economy and environmental protection issues. Numerous studies have now found that transition metal carbide MXenes are ideal candidates as catalysts for the hydrogen evolution reaction. However, MXenes are inclined to easily undergo lamellar structure agglomeration and stacking, which impedes their further applications.

Production of selenium-enriched peptide using immobilized Alcalase on FeO modified by tannic acid and polyethyleneimine.

Enzymatic synthesis of selenium (Se)-enriched peptides is vital for their application in supplementing organic Se. However, the poor stability and reusability of the free enzyme impedes the reaction. In this work, a highly stable immobilized Alcalase was synthesized by immobilizing Alcalase on tannic acid (TA) and polyethyleneimine (PEI) modified FeO nanoparticles (NPs).