Sensors (Basel)
January 2025
University-Industrial Cooperation Corps of HiVE Center, Wonkwang Health Science University, 514, Iksan-daero, Iksan-si 54538, Republic of Korea.
Virtual reality (VR) technology has gained popularity across various fields; however, its use often induces cybersickness, characterized by symptoms such as dizziness, nausea, and eye strain. This study investigated the differences in cybersickness levels and head movement patterns under three distinct VR viewing conditions: dynamic VR (DVR), static VR (SVR), and a control condition (CON) using a simulator. Thirty healthy adults participated, and their head movements were recorded using the Meta Quest 2 VR headset and analyzed using Python.
View Article and Find Full Text PDFSci Rep
January 2025
Ministry of Sports, Hubei Institute of Automotive Industry, Shiyan, 442002, Hubei, China.
The objective of the present study was to examine the impact of different plyometric training (PT) surfaces on the adaptive changes of jumping ability, sprinting speed, change of direction ability and strength performance in volleyball players. Forty male players participated in the study and were divided into four equal groups performing PT in aquatic (APT), sand (SPT), and land (LPT) surfaces, or an active control group (CON). All training groups indicated small to large significant (p = 0.
View Article and Find Full Text PDFJ Pharmacopuncture
December 2024
Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
Objectives: This study assessed the electrocardiographic pattern and cardiac inflammatory response of doxorubicin-induced myocardial injury in Wistar rats treated with ethanol extract.
Methods: Female Wistar rats (190-200 g) were assigned into five groups of seven rats each. The Group 1 (Control group) was given rat chow and drinking water while the Group 2 (doxorubicin group) received intraperitoneal administration of doxorubicin (2 mg/kg) once weekly for three weeks.
J Pharmacopuncture
December 2024
Department of Preventive Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Republic of Korea.
Objectives: Among the various treatment methods involving the use of natural substances, pharmacopuncture using animal venom is a relatively new form of acupuncture that has been developed in South Korea and is gaining popularity worldwide. Pharmacopuncture with animal venom is widely used in clinical practice; therefore, ensuring its procedural safety is crucial. This study aimed to evaluate the safety and toxicity of pharmacopuncture using animal venom.
View Article and Find Full Text PDFJ Adv Res
December 2024
School of Korean Medicine, Gachon University, Seongnam 13110, Republic of Korea. Electronic address:
Introduction: Network pharmacology has gained significant traction as a tool for identifying the mechanisms and therapeutic effects of herbal medicines. However, despite the usefulness of these approaches, their diversity underscores the critical need for a systematic evaluation to ensure consistency and reliability.
Objectives: We aimed to evaluate the network pharmacological analyses, focusing on identifying the mechanisms and therapeutic effects of herbal medicines.
Vet Sci
December 2024
College of Veterinary Medicine and Bio-Safety Research Institute, Jeonbuk National University, Iksan Campus, Gobong-ro 79, Iksan 54596, Republic of Korea.
Bacterial skin infections, particularly pyoderma and otitis externa, are widespread in dogs, primarily caused by and species. This study evaluates the prevalence and types of bacterial pathogens in affected dogs in South Korea using a meta-analytical approach. Following the PRISMA guidelines, five electronic databases were searched for relevant studies published between 1990 and 2024.
View Article and Find Full Text PDFTranspl Int
December 2024
Department of General, Visceral, and Pediatric Surgery, University Medical Center Göttingen, Göttingen, Germany.
The scarcity of donors has prompted the growing utilization of steatotic livers, which are susceptible to injuries following orthotopic liver transplantation (OLT). This study aims to assess the efficacy of multidrug donor preconditioning (MDDP) in alleviating injuries of steatotic grafts following rat OLT. Lean rats were subjected to a Western-style diet with high-fat (HF) and high-fructose (HFr) for 30 days to induce steatosis.
View Article and Find Full Text PDFNutrients
November 2024
Department of Food and Biotechnology, Woosuk University, Wanju 55338, Jeonbuk-do, Republic of Korea.
Background/objectives: In aerobic organisms, such as humans, oxygen radicals are inevitably produced. To counteract oxidation, the body generates antioxidant substances that suppress free radicals. However, levels of reactive oxygen species (ROS) increase due to aging and lifestyle factors, leading to exposure to various diseases.
View Article and Find Full Text PDFNutr Metab Cardiovasc Dis
November 2024
College of Pharmacy, Kyung Hee University, Seoul, Republic of Korea; Department of Regulatory Science, Graduate School, Kyung Hee University, Seoul, Republic of Korea; Institute of Regulatory Innovation Through Science, Kyung Hee University, Seoul, Republic of Korea. Electronic address:
Background And Aims: In contrast to the substantial body of clinical trial evidence, the real-world evidence regarding the efficacy of statins in the prevention of cardiovascular events among patients with type 2 diabetes mellitus (T2DM) is relatively limited. Therefore, we assessed the effectiveness of atorvastatin for the primary prevention of CV events in patients with T2DM, using a population-based data in South Korea.
Methods And Results: This retrospective cohort study was conducted using the National Health Insurance Service Customized Database (2008-2018) in South Korea.
J Hazard Mater
November 2024
Department of Health Sciences, The Graduate School of Dong-A University, Busan 49315, Republic of Korea; Department of Biomedical Sciences, College of Natural Science, Dong-A University, Busan 49315, Republic of Korea. Electronic address:
The effect of atmospheric ultrafine particulate matter (UPM) on respiratory allergic diseases has been investigated for decades; however, the precise molecular mechanisms underlying these effects remain poorly understood. In this study, we used a simulated UPM (sUPM) generated via the spark discharge method to refine black carbon, a core particle that closely mimics real-world UPM, including the size (i.e.
View Article and Find Full Text PDFPharmaceutics
November 2024
College of Pharmacy, Woosuk University, Wanju 55338, Republic of Korea.
Inflammatory bowel disease (IBD) is a complex and chronic condition that requires the use of various pharmacological agents for its management. Despite advancements in IBD research, the multifaceted mechanisms involved continue to pose significant challenges for strategic prevention. Therefore, it is crucial to prioritize safe and effective treatment strategies using the currently available pharmacological agents.
View Article and Find Full Text PDFToxins (Basel)
November 2024
Department of Policy Development, National Institute for Korean Medicine Development, Seoul 04516, Republic of Korea.
Managing shoulder pain typically involves the use of acetaminophen or oral nonsteroidal anti-inflammatory drugs, but prolonged use of these medications can lead to dependence and various side effects. To overcome the dose dependency and side effects of these conventional drugs, animal venoms have begun to be utilized. Among them, bee venom stands out for its powerful anti-inflammatory properties, which help relieve pain and treat chronic inflammatory conditions.
View Article and Find Full Text PDFCurr Issues Mol Biol
October 2024
College of Korean Medicine, Wonkwang University, Iksan 54538, Republic of Korea.
Psoriasis is a chronic inflammatory skin disorder characterized by the hyperproliferation of keratinocytes and immune system dysregulation, with significant needs due to the limitations and adverse effects of current treatments. In this study, we sought to discover novel herbal candidates and their active compounds for psoriasis by leveraging a multiscale network analysis. We conducted a comprehensive analysis of data from 348 medicinal herbs and their active compounds, identifying , , , and as top candidates without reported evidence.
View Article and Find Full Text PDFHosp Pharm
October 2024
Graduate School of Converging Clinical and Public Health, Ewha Womans University, Seoul, Republic of Korea.
Patients in neurocritical care units are particularly vulnerable to medication errors and adverse drug events, necessitating specialized care and comprehensive pharmacological management. Despite this need, the scarcity of clinical pharmacist specialists in South Korean hospitals results in limited direct patient care within multidisciplinary teams. This study aimed to evaluate the impact of a dedicated pharmacy service program in the neurocritical care intensive care unit (neuro-ICU) on patient outcomes and to propose a clinical pharmacy service model tailored for resource-limited settings.
View Article and Find Full Text PDFKorean J Physiol Pharmacol
January 2025
College of Pharmacy and Research Institute of Pharmaceutical Sciences, Woosuk University, Wanju 55338, Korea.
The proliferation and migration of vascular smooth muscle cells (VSMCs) are key contributors to the development of atherosclerosis and restenosis. We investigated the impact of rosuvastatin (RSV) on platelet-derived growth factor (PDGF)-BB-induced proliferation and migration of VSMCs, with a focus on the Akt/mTOR-autophagy signaling pathways. The cytotoxicity of RSV was assessed using MTT and annexin V staining, while the proliferation and migration capabilities of PDGF-BB-induced VSMCs were evaluated using MTT and cell migration assays.
View Article and Find Full Text PDFFront Psychol
October 2024
Laboratory of Sports Conditioning, Nutrition Biochemistry and Neuroscience, Department of Sport Science, College of Arts and Sports, University of Seoul, Dongdaemun-gu, Seoul, Republic of Korea.
Introduction: There is limited evidence that the psychological characteristics of athletes with disabilities are identical to those of non-disabled athletes, owing to differences in ecological traits, and there is insufficient information on how athletes with disabilities perceive disabled athletes' perception of errors, challenges, and deliberate practice. Therefore, it is necessary to examine whether the causal model of the perception of errors, challenge, and deliberate practice will be reproduced in the same way as in non-disabled athletes. Therefore, this study aimed to verify a causal model of the perception of errors, challenges, and deliberate practice by athletes with disabilities.
View Article and Find Full Text PDFNat Prod Res
November 2024
College of Pharmacy, Woosuk University, Wanju, Republic of Korea.
Multidrug resistance is a crucial factor contributing to the failure of cancer treatment. Multidrug resistance protein 1 (MDR1) is the most relevant efflux transporter associated with multidrug resistance. The objective of this study was to identify potent MDR1 inhibitors from flavonols.
View Article and Find Full Text PDFSci Rep
November 2024
General Graduate School, Woosuk University, Wanju-gun, Jeollabuk-do, 55338, Republic of Korea.
In this work, a control strategy based on fuzzy sliding mode control (FSMC) is applied to effectively manage the large-amplitude chaotic vibrations exhibited by a simply supported beam. The analysis considers the nonlinear beam structure, which is subjected to an external load. Hamilton's principle is employed, and the equations of motion are derived for the studied structure.
View Article and Find Full Text PDFSci Rep
November 2024
General Graduate School, Woosuk University, Wanju-gun, Jeollabuk-do, 55338, Republic of Korea.
A new control approach based on fuzzy sliding mode control (FSMC) is proposed to regulate the chaotic vibration of an axial string. Hamilton's principle is used to formulate the nonlinear equation of motion of the axial translation string, and the von Kármán equations are used to analyse the geometric nonlinearity. The governing equations are nondimensionalized as partial differential equations and transformed into a nonlinear 3-dimensional system via the third-order Galerkin approach.
View Article and Find Full Text PDFJ Photochem Photobiol B
December 2024
College of Pharmacy, Dongduk Women's University, Seoul 02748, Republic of Korea. Electronic address:
Photodynamic therapy (PDT) is known to trigger immunogenic cell death (ICD), leading to an anticancer effect even in untreated metastatic cancer, a phenomenon called the "abscopal effect". Furthermore, ICD induction activates an immune response, which may synergize with immunotherapy. The objective of our research was to evaluate the anticancer efficacy of combining PDT with immunotherapy.
View Article and Find Full Text PDFInt J Ment Health Nurs
October 2024
Physical Education Institute, Woosuk University, Wanju, South Korea.
Mental health (MH) differences remain an issue in contemporary Chinese society, with various factors influencing individuals' well-being. This study investigates the complex connection between results related to psychological wellness and social issues, integrating cultural, psychological and technological perspectives. Through a quantitative research methodology, data were collected from 1000 individuals using a questionnaire survey and analysed using SPSS software.
View Article and Find Full Text PDFHealthcare (Basel)
October 2024
Institution of Sport Contents, Andong National University, Anndong-si 36729, Gyeongsangbuk-do, Republic of Korea.
Objectives: As the Republic of Korea transitions towards a super-aged society, the health and mental well-being of older adults are emerging as critical issues. While many researchers are focusing on successful aging among older adults who participate in exercise, there is a research gap in the Korean literature regarding the preconditions that foster this outcome. Therefore, this study analyzed the relationship between satisfaction and exercise, physical self-efficacy (PSE), exercise adherence, and successful aging among Korean older adults who exercise regularly.
View Article and Find Full Text PDFFood Funct
October 2024
Clinical Trial Center for Functional Foods, Biomedical Research Institute, Jeonbuk National University Hospital, Jeonju 54907, Republic of Korea.
The human immune system plays a crucial role in defending the body against various infections, viruses, and external substances, contributing to overall well-being. However, an imbalance in the immune system can lead to increased susceptibility to infections, impacting overall health. Preclinical investigations suggest the potential application of L.
View Article and Find Full Text PDFBiochem Biophys Res Commun
November 2024
Orthopedics Department, Norinco General Hospital, Xi'an, 710065, Shaanxi, China. Electronic address:
Skeletal muscle ischemia-reperfusion injury (IRI) is a common severe disease with a complex pathological process. This study found that copper chloride (CuCl) inhibited cell viability in a concentration dependent manner, increased intracellular copper levels and downregulated copper transporter 1 (CTR1) expression. CTR1 upregulation promoted copper uptake by myoblasts and then enhanced cuproptosis, leading to a significant increase in the levels of dihydrolipoamide S-acetyltransferase (DLAT) oligomers, while a significant decrease in the levels of lipoylated (Lip)-dihydrolipoamide S-succinyltransferase (DLST) and Lip-DLAT, ultimately inhibiting cell viability and inducing cell injury.
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