2 results match your criteria: "Wonkwang-Oriental Medicines Research Institute Wonkwang University[Affiliation]"
Toxicological Evaluation of a Polyherbal Formulation (18KHT01) and Validation of UPLC-DAD Method for Quality Control.
Biomed Res Int
September 2024
Department of Oriental Pharmacy and Wonkwang-Oriental Medicines Research Institute Wonkwang University, Sinyong-Dong, Iksan 570-749, Republic of Korea.
18KHT01 is a novel synergistic composition of , , , and a small portion of . Our previous report demonstrated that the 18KHT01 exhibits potent antiobesity effects, with synergistic antioxidant, antiadipogenic, and antiobesity activities in diet-induced obese mice. This study explores the toxicity profile and quality control parameters of the 18KHT01 formulation.
View Article and Find Full Text PDFRubrofusarin-6-β-gentiobioside inhibits lipid accumulation and weight gain by regulating AMPK/mTOR signaling.
Phytomedicine
September 2019
Department of Oriental Pharmacy, College of Pharmacy, Wonkwang-Oriental Medicines Research Institute Wonkwang University, 460 Iksandae-ro, Iksan, Jeonbuk 54538, Republic of Korea. Electronic address:
Background: Although rubrofusarin-6-β-gentiobioside (RFG), which is a component of Cassiae tora seed, could likely regulate hyperlipidemia, its anti-obesity effect and related mechanism have not been elucidated.
Purpose: The aim of this study was to examine whether RFG can ameliorate obesity and the mechanism of lipid accumulation regulated by RFG.
Study Design: In in vitro experiments, we confirmed the anti-adipogenic effect of RFG using 3T3-L1 cells and human adipose mesenchymal stem cells (hAMSCs).