Integrated geophysical and geospatial techniques for surface and groundwater modeling.

An integrated approach using geophysical and geospatial techniques was employed to model the surface and subsurface water-bearing strata and assess aquifer vulnerability in the Sehnsa town, Kotli district, State of Azad Kashmir, Pakistan. The inadequate scientific studies in the hilly terrain with such complex geological conditions has led to the failure of the boreholes for groundwater extraction. For the evaluation of groundwater potential and subsurface lithology, 30 vertical electrical soundings (VES) stations utilizing the Schlumberger electrode configuration were completed, modeled and analyzed spatially.

Homogeneous Integration of Polyoxometalates and Titania into Crumpled Layers.

The crumpling and buckling in nanosheets are anticipated to provide new characteristics that could not be observed in ideal flat layers. However, the rigid lattice structure of inorganic metal oxides limits their assembly into well-defined crumpled layers. Here, this study demonstrates that at the sub-nm scale, polyoxometalates (POMs) clusters having well-defined structures can intercede during the nucleation process of titania and co-assemble with nuclei to form uniform, large-sized crumpled binary 2D layers with a thickness of 2 nm.

A Novel Missense Variant in the Underlies Spondyloepiphyseal Dysplasia with Congenital Joint Dislocations.

Background: Spondyloepiphyseal dysplasia (SED) is characterized by skeletal dysplasia and multiple joint dislocations. SEDs encompass various types, such as SED congenita, SED tarda (SED-T), SED with congenital joint dislocations (SED-CJD), SED stanescu, and SED-T with progressive arthropathy.

Methods And Results: In the present study, we clinically and genetically characterized a consanguineous Pakistani family with SED-CJD.

Novel Synthesis of Zinc Oxide on Cotton Fabric by Cathodic Cage Plasma Deposition for Photocatalytic and Antibacterial Performance.

Cotton fabrics with zinc oxide (ZnO) coating are of significant interest due to their excellent antibacterial performance. Thus, they are widely in demand in the textile industry due to their medical and hygienic properties. However, conventional techniques used to deposit ZnO on fabric require long processing times in deposition, complex and expensive equipment, and multiple steps for deposition, such as a separate process for nanoparticle synthesis and subsequent deposition on fabric.

Electrical transport and dielectric relaxation mechanism in ZnCdFeO spinel ferrite: A temperature- and frequency-dependent complex impedance study.

In the present study, the frequency-dependent dielectric relaxation and electrical conduction mechanisms in sol-gel-derived ZnCdFeO (ZCFO) spinel ferrite were studied in the temperature range of 343-438 K. The formation of the ZCFO spinel ferrite phase with space group Fd3m was confirmed by X-ray diffraction analysis. The dielectric relaxation and electrical conduction mechanisms were studied using complex impedance spectroscopy (CIS).

Foraging for the future: traditional culinary uses of wild plants in the Western Himalayas-Kashmir Valley (India).

Background: In the intricate tapestry of food security, wild food species stand as pillars, nourishing millions in low-income communities, and reflecting the resilience and adaptability of human societies. Their significance extends beyond mere sustenance, intertwining with cultural traditions and local knowledge systems, underscoring the importance of preserving biodiversity and traditional practices for sustainable livelihoods.

Methods: The present study, conducted between February 2022 and August 2023 along the Line of Control in India's Kashmir Valley, employed a rigorous data collection encompassing semi-structured interviews, focus group discussions, and specific field observations facilitated through a snowball sampling technique.

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RNA-dependent liquid-liquid phase separation (LLPS) proteins play critical roles in cellular processes such as stress granule formation, DNA repair, RNA metabolism, germ cell development, and protein translation regulation. The abnormal behavior of these proteins is associated with various diseases, particularly neurodegenerative disorders like amyotrophic lateral sclerosis and frontotemporal dementia, making their identification crucial. However, conventional biochemistry-based methods for identifying these proteins are time-consuming and costly.

Corrigendum: Sesquiterpene lactones attenuate paclitaxel resistance via inhibiting MALAT1/STAT3/ FUT4 axis and P-Glycoprotein transporters in lung cancer cells.

[This corrects the article DOI: 10.3389/fphar.2022.

Ethnopharmacological uses of fauna among the people of central Punjab, Pakistan.

Introduction: The utilization of fauna and fauna-based byproducts in ethnomedicinal usages has been a longstanding human activity, practiced across various cultures worldwide. This study focuses on investigating the utilization of animal-based traditional medicine by the people of Pakistan, specifically in the Gujranwala area.

Methods: Data collection took place from January to September 2019 through interviews with local communities.

Synergetic Effects of Sericin and Turmeric on Burn Wound Healing in Mice.

Burn wounds are one of the most hazardous issues, globally. Silkworm produces a protein called sericin. Sericin assists in wound healing by facilitating the proliferation of keratinocytes and fibroblasts, while turmeric is potentially helpful in wound healing because of its antioxidant, anti-inflammatory, and anti-infectious activities.

Dynamics of the time-fractional reaction-diffusion coupled equations in biological and chemical processes.

This paper aims to demonstrate a numerical strategy via finite difference formulations for time fractional reaction-diffusion models which are ubiquitous in chemical and biological phenomena. The time-fractional derivative is considered in the Caputo sense for both linear and nonlinear problems. First, the Caputo derivative is replaced with a quadrature formula, then an implicit method is used for the remaining part.

Silver-infused TiO nanowires and unveiling their potential for superior wastewater dye remediations.

Silver infused ultrathin TiO nanowires (NWs) were synthesized via a single step solvothermal approach. The crystallinity, structure, and morphology were determined to understand the physicochemical nature of the nanocomposites. The catalytic efficiency of the newly synthesized nanocatalysts was tested for the textile waste treatment taking methylene blue (MB) as model pollutant under solar light irradiations.

Antibacterial, antioxidant, and anticancer potential of green fabricated silver nanoparticles made from Viburnum grandiflorum leaf extract.

Background: Recently, researchers are focusing on creating new tools to combat the antibiotic resistant bacteria and malignancy issues, which pose significant threats to humanity. Biosynthesized silver nanoparticles (AgNPs) are thought to be a potential solution to these issues. The biosynthesis method, known for its environmentally friendly and cost-effective characteristics, can produce small-sized AgNPs with antimicrobial and anticancer properties.

Polyoxometalate Induced Assembly Into Surface Functionalized Multidimensional Heterostructures with Enhanced Catalytic Activity.

The self-assembly of inorganic nanocrystals offers an efficient way for the fabrication of functional materials. However, it is still challenging for the construction of multidimensional nanostructures with controllable shapes, compositions and functions. Here, a series of heterostructures in different dimensions by surface modification of polyoxometalate (POM) clusters is developed.

Montmorillonite modified Ni/Mg/Al ternary layered double hydroxide nanoflowers with enhanced adsorption features.

A hydrothermal technique was employed to synthesize Ni/Mg/Al ternary L.D.H.

Process optimization, antioxidant, antibacterial, and drug adjuvant properties of bioactive keratin microparticles derived from porcupine () quills.

A structural protein called keratin is often employed in the medical industry to create medication carriers. Process improvement, antioxidant, antibacterial, and adjuvant drug studies of synthetic bioactive keratin microparticles made from lipids and keratin derived from porcupine () quills are the main objectives of this study. After coating the keratin microparticles with lipids which were obtained from the same porcupine quills, the bioactive keratin microparticles were produced.

The optimal control chart selection for monitoring COVID-19 phases: a case study of daily deaths in the USA.

Epidemiologists frequently adopt statistical process control tools, like control charts, to detect changes in the incidence or prevalence of a specific disease in real time, thereby protecting against outbreaks and emergent health concerns. Control charts have proven essential in instantly identifying fluctuations in infection rates, spotting emerging patterns, and enabling timely reaction measures in the context of COVID-19 monitoring. This study aims to review and select an optimal control chart in epidemiology to monitor variations in COVID-19 deaths and understand pandemic mortality patterns.

Understanding multidimensional poverty in pakistan: implications for regional and demographic-specific policies.

This study enriches the limited literature on multidimensional poverty by focusing on household demographic characteristics as determinants of household-specific living arrangements in Pakistan. The study employs the Alkire and Foster methodology to measure the multidimensional poverty index (MPI) using data drawn from the latest available nationally representative Household Integrated Economic Survey (HIES 2018-19). The analysis investigates multidimensional poverty levels among households in Pakistan according to various criteria (such as access to education and healthcare, basic living standards, and monetary status) and how they differ across Pakistan's regions and provinces.

Dammarane-type triterpene saponins from the roots of Panax notoginseng (Burk.) F. H. Chen and their neuroprotective effects.

Three undescribed dammarane-type triterpene saponins, 20(S)-sanchirhinoside A-A (1-3), together with seventeen known ones, were isolated from the roots of Panax notoginseng (Burk.) F. H.

Molecular phylogenetics and diversity of the Himalayan shrew ( Soriculus nigrescens Gray, 1842) (Eulipotyphla, Soricidae) in Southwest China.

The Himalayan shrew, Soriculus nigrescens Gray, 1842, belongs to the monotypic genus Soriculus, which is distributed mainly in the Himalayan region. Previous authors have studied its classification based on morphological and molecular data. However, no comprehensive study of the diversity and phylogeny of this species has been performed.

Quantification of the Quercetin Nanoemulsion Technique Using Various Parameters.

Natural antioxidant polyphenolic compounds obtained from different plants are considered antioxidants for curing various chronic pathological diseases such as cardiovascular disorders and cancer. Quercetin (a polyphenolic flavonol) has attracted much attention from dietitians and medicinal chemists due to its wide variety of pharmacological activities, including anti-diabetic, anti-hypertensive, anti-carcinogenic, anti-asthmatic, anti-viral, and antioxidant activities. Furthermore, structurally, it is well suited to stabilize emulsions.

Pharmacological intervention of biosynthesized silver nanoparticles against hexavalent chromium induced toxicity in male albino mice.

Hexavalent chromium, toxic heavy metal, among the top-rated environmental contaminants, is declared a potent endocrine disruptor in humans and animals. The present study was planned to find harmful effects on the reproductive system caused by Cr (VI) and the ameliorative effect of and -mediated AgNP on male mice (). In the present study, known infertility medicine, clomiphene citrate is also used as a positive control.

Ameliorative effect of conjugated silver nanoparticles against chromium-induced hepatotoxicity and renal toxicity in mice.

Hexavalent chromium induces oxidative stress in the liver and kidney. Therefore an study was designed to investigate the modulatory effect of biosynthesized AgNP against Cr (VI) induced hepatotoxicity and nephrotoxicity. The organs index, serum level of ALT, AST, ALP, MDA, total protein and creatinine were measured.

Soret and Dufour influences on forced convection of Cross radiative nanofluid flowing via a thin movable needle.

The main feature of the current investigation is to analyze the magnetohydrodynamic mixed convection flow of Cross fluid. Flow is due to a movable thin needle with Soret and Dufour effect. Heat generation/absorption and nonlinear heat radiation are used in the energy equation.