The role of non-invasive stress testing in the diagnosis of coronary microvascular disease.

Background: Angina with non-obstructive coronary artery disease (ANOCA) is commonly observed in patients with stable angina undergoing coronary angiography. Current guidelines recommend non-invasive stress testing as the first step in diagnosing coronary microvascular disease (CMD). This study aims to evaluate the diagnostic value of non-invasive stress testing in patients invasively diagnosed with CMD.

Maternal shift work during pregnancy and cardiovascular health impacts on mother and offspring.

Cardiovascular disease (CVD) is the leading cause of death for women worldwide. One of the risk factors for CVD in women is complications during pregnancy. Pregnancy complications include a wide arena of pathologies, including hypertension, preeclampsia, gestational diabetes, preterm delivery and miscarriage.

Vulnerable Neonates (and Their Families) Deserve Respectful Care.

Respectful maternity care (RMC) is a topic that has received increasing focus among clinicians, researchers, and the public in recent years. While clinicians recognize the importance of respectful care, patients report that they are not consistently receiving it. The Association of Women's Health, Obstetric and Neonatal Nurses (AWHONN) created the RMC Framework, Evidence-Based Guidelines and Implementation Toolkit to provide nursing teams with the knowledge, tools, and structures they need to promote RMC.

Comparative analysis of injuries related to self-harm, assault, and intimate partner violence: insights from U.S. Emergency Departments (2005-2021).

Background: Emergency departments are on the front lines of non-fatal self-harm injury (SHI). This study identifies patterns in patients presenting to emergency departments with SHI compared with patients presenting with assault and intimate partner violence.

Methods: Using the National Electronic Injury Surveillance System All Injury Program database, we analyzed SHI cases in the emergency department from 2005 to 2021 and examined demographic characteristics, injury mechanism and anatomic location, emergency department disposition and temporal patterns relative to cases involving assault and intimate partner violence.

Injury risk factors and their priority for mitigation in women's netball: a systematic review and Delphi consensus.

This study aimed to establish consensus on injury risk factors in netball via a combined systematic review and Delphi method approach. A systematic search of databases (PubMed, Scopus, MEDLINE, SPORTDiscus and CINAHL) was conducted from inception until June 2023. Twenty-four risk factors were extracted from 17 studies and combined with a three-round Delphi approach to achieve consensus.

Reliability of the OMERACT Giant cell arteritis Ultrasonography Score (OGUS): results of a patient-based exercise involving experts and non-experts in vascular ultrasonography.

Objective: To test the reliability of the Outcome Measures in Rheumatology Giant cell arteritis (GCA) Ultrasonography Score (OGUS) and other composite scores in a patient-based exercise involving experts and non-experts in vascular ultrasonography.

Methods: Six GCA patients were scanned twice (two rounds separated ≥3 hours) by 12 experts and 12 non-experts. Non-experts received 90 min of theoretical and 240 min of practical training between rounds 1 and 2.

Unintentional exposure to leuprolide acetate during early pregnancy with a huge intramural myoma.

Leuprolide acetate is commonly used to reduce the size of myomas before surgery. Initially, it stimulates pituitary gonadotropin secretion, followed by sustained suppression of gonadal function. However, the impact on pregnancy outcomes from inadvertent exposure remains unclear.

Isolated third cranial nerve palsy in benign idiopathic intracranial hypertension.

Idiopathic intracranial hypertension (IIH) is marked by increased intracranial pressure without any accompanying evidence of clinical, imaging or laboratory findings of intracranial pathology. In addition to headache, nausea and vomiting, typical symptoms might also include diplopia, photophobia and blurred vision. Third nerve palsy is rarely linked to IIH, although sixth nerve palsy is reported in the majority of individuals with IIH.

Anaesthetic management of laparotomy in a patient with anti-NMDA receptor antibody-mediated encephalitis.

Management of cases of anti-N-methyl-D-aspartate (NMDA) antibody-mediated encephalitis is very challenging to anaesthesiologists as this receptor is the target of many anaesthetics. We report a woman diagnosed with anti-NMDA antibody-mediated encephalitis posted for laparotomy. She presented with generalised tonic-clonic seizures.

Bona fide diminished ovarian reserve or profound ovarian suppression by long-term oral contraceptive use?

Combined oral contraceptives (COCs) are widely used by reproductive-aged women. Current data suggest that long-term use of COCs can suppress ovarian reserve markers, including anti-mullerian hormone and antral follicle count, which may negatively impact ovarian response and oocyte yield in patients undergoing planned oocyte cryopreservation to preserve future reproductive potential. Discontinuation of COCs can improve ovarian stimulation outcomes, though the ideal duration of cessation is unknown.

DPPX antibody-mediated disease mimicking Wernicke's encephalopathy.

Anti-dipeptidyl-peptidase-like protein 6 antibody-mediated disease is a rare autoimmune encephalitis typically presenting with diarrhoea and/or weight loss, central nervous system hyperexcitability and cognitive dysfunction. We present a case of a young woman with 10 days of diplopia and unsteadiness in the context of dysthymia and significant weight loss over 2 months. Initial examination demonstrated mixed dysconjugate nystagmus and ataxic gait.

Demographic and clinical impact on preoperative BREAST-Q ePROM completion and baseline outcomes in women undergoing breast cancer surgery: a quantitative descriptive study at a Danish university hospital.

Objectives: This study aimed to investigate patients' use of electronic Patient-Reported Outcome Measures (ePROMs) and understand the demographic and clinical factors that may be correlated with patient responses to the BREAST-Q at the preoperative stage of breast cancer. The BREAST-Q is a PROM in questionnaire format, developed and validated to assess satisfaction and quality of life for breast surgery patients.The hypothesis tested is that considering disparities in geography, age and education among responders is essential for capturing a diverse patient population in future Patent-Reported Outcome Measures initiatives, examining how these characteristics are associated with Patent-Reported Outcome Measures utilisation and outcomes.

Non-utilisation of postpartum services in northwestern Nigeria: analyses of trend and social determinants from 2003 to 2018.

Objective: To assess the prevalence of non-utilisation of postpartum services in northwestern Nigeria from 2003 to 2018 and to identify and estimate the influence of social determinants, a crucial step in improving maternal and child health in the region.

Design: The 2003, 2008, 2013 and 2018 Nigeria Demographic and Health Survey rounds were used. Descriptive, trend and multivariable logistic regression analyses were used to show the trend and assess the influence of social determinants.

Is economic inequality in maternal and child healthcare decreasing in India? Trends between 2005-2006, 2015-2016 and 2019-2021.

Objective: This study examined economic inequality in coverage of selected maternal and child healthcare (MCH) indicators in India and its states over the last 15 years.

Design: The study analysed last three rounds of the National Family Health Survey data, conducted during 2005-2006, 2015-2016 and 2019-2021. Bivariate analyses, ratio of richest to poorest, slope index of inequality (SII) and multivariate binary logistic regression analyses were used to examine the coverage as well as inequalities in the outcome indicators for India and its states and at district level.

Providing medically tailored groceries and food resource coaching through the charitable food system to patients of a safety-net clinic in Dallas, Texas: a randomised controlled trial protocol.

Introduction: Linking patients living with chronic, diet-related diseases and food insecurity to charitable food assistance, medically tailored groceries (MTGs) and food resource coaching may empower patients to better manage their health in a way that is economically sustainable. This protocol paper describes the implementation of a study evaluating MTGs and food resource coaching in a food pantry setting.

Methods And Analysis: A randomised controlled trial whereby patients of a safety-net health centre will be screened for The Emergency Food Assistance Program (TEFAP) and study eligibility.

Predictive value of cough peak flow for successful extubation in mechanically ventilated patients after craniotomy: a single-centre prospective diagnostic study.

Objectives: The purpose of this study was to evaluate the predictive value of the cough peak flow (CPF) for successful extubation in postcraniotomy critically ill patients.

Design: This was a single-centre prospective diagnostic study.

Setting: The study was conducted in three intensive care units (ICUs) of a teaching hospital.

Identifying the burdens for informal caregivers of tracheostomy-dependent people: a scoping review protocol.

Introduction: It is complicated and time-consuming to care for tracheostomised patients, and many informal caregivers are said to feel a variety of burdens, although we are unsure of the specifics of this burden. This scoping review aims to identify and examine the caregiver burden encountered by informal caregivers of patients with tracheostomy.

Methods And Analysis: This scoping review will be carried out in accordance with Arksey and O'Malley and its extended framework, along with adherence to the guidelines provided by the Joanna Briggs Institute.

Trends in Medical Students' Legal Concerns Regarding Abortion Care in the Wake of the 2022 Decision.

Objectives: The 2022 US Supreme Court decision dramatically shifted the legal landscape in health care, leaving state legislatures to redefine the ethics of medical practice. As gold-standard medical procedures become banned and criminalized, physicians are facing heightened legal uncertainty and grappling with moral dilemmas of where and how to practice. This study aimed to quantitatively assess trends in legal concern among medical students and identify correlations with decision making regarding future medical training.

Development and Validation of a Nomogram-Based Model to Predict Primary Hypertension Within the Next Year in Children and Adolescents: Retrospective Cohort Study.

Background: Primary hypertension (PH) poses significant risks to children and adolescents. Few prediction models for the risk of PH in children and adolescents currently exist, posing a challenge for doctors in making informed clinical decisions.

Objective: This study aimed to investigate the incidence and risk factors of PH in Chinese children and adolescents.

A Digital Parenting Intervention With Intimate Partner Violence Prevention Content: Quantitative Pre-Post Pilot Study.

Background: Intimate partner violence (IPV) and violence against children are global issues with severe consequences. Intersections shared by the 2 forms of violence have led to calls for joint programming efforts to prevent both IPV and violence against children. Parenting programs have been identified as a key entry point for addressing multiple forms of family violence.

Enhancing Access to Mental Health Services for Antepartum and Postpartum Women Through Telemental Health Services at Wellbeing Centers in Selected Health Facilities in Bangladesh: Implementation Research.

Background: Globally, 10% of pregnant women and 13% of postpartum women experience mental disorders. In Bangladesh, nearly 50% of mothers face common mental disorders, but mental health services and trained professionals to serve their needs are scarce. To address this, the government of Bangladesh's Non-Communicable Disease Control program initiated "Wellbeing Centers," telemental health services in selected public hospitals.

Pediatric Providers' Perceptions of Their Role in the Early Detection of Postpartum Depression.

Objective: To explore pediatric health care providers' perceptions of their role in screening mothers for postpartum depression (PPD).

Design: Descriptive, qualitative methodology.

Setting: Pediatric care providers from five different institutions in the Chicagoland area.

An Educational Intervention to Improve Clinician Vitamin D Teaching for Parents of Human Milk-Fed Infants.

Objective: To increase the number of episodes of vitamin D teaching in the primary care setting for parents of human milk-fed infants and to explore pediatric clinicians' knowledge of vitamin D supplementation in human milk-fed infants and their perception of project intervention usefulness.

Design: Quality improvement project using a quasi-experimental, pretest-posttest design.

Setting/local Problem: Despite recommendations from the American Academy of Pediatrics, vitamin D supplementation adherence rates for human milk-fed infants remain low.

Risk of disruptive behavioural disorders in offspring of mothers with perinatal depressive disorders: A data linkage cohort study.

Background: This study aims to examine the relationship between maternal antenatal and postnatal depressive disorders and the risk of disruptive behavioural disorders (DBDs) in offspring, including conduct disorder (CD) and oppositional defiant disorder (ODD), to enhance understanding and address gaps in the literature.

Methods: We utilised a large administrative health dataset from New South Wales (NSW), Australia. Maternal perinatal depressive disorders and offspring DBDs were identified using International Classification of Diseases (ICD-10) codes.

Neutrophil extracellular traps promote pre-metastatic niche formation in the omentum by expanding innate-like B cells that express IL-10.

Disseminated cancer cells in the peritoneal fluid often colonize omental fat-associated lymphoid clusters but the mechanisms are unclear. Here, we identify that innate-like B cells accumulate in the omentum of mice and women with early-stage ovarian cancer concomitantly with the extrusion of chromatin fibers by neutrophils called neutrophil extracellular traps (NETs). Studies using genetically modified NET-deficient mice, pharmacologic inhibition of NETs, and adoptive B cell transfer show that NETs induce expression of the chemoattractant CXCL13 in the pre-metastatic omentum, stimulating recruitment of peritoneal innate-like B cells that in turn promote expansion of regulatory T cells and omental metastasis through producing interleukin (IL)-10.