1,052 results match your criteria: "Women's Health Institute[Affiliation]"

Introduction: Many transgender individuals seeking healthcare have had at least one negative experience related to being transgender. As a result, transgender patients may forego seeking healthcare treatment atall, leading to adverse long-term health outcomes. With barriers to care and oftentimes suboptimal care provided to transgender individuals, TranZap, in collaboration with the PROUD Gender Center of NJ, was commenced.

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Article Synopsis
  • Studies indicate that adverse sexual function is linked to medical conditions like diabetes and heart disease, but there is little data on sexual dysfunction in female patients with spinal pathologies requiring surgery.
  • * The narrative review aimed to gather existing information on female sexual dysfunction related to spinal issues, emphasizing the need for recognition and action in clinical settings.
  • * Findings reveal that spinal issues can lead to various sexual dysfunctions, with many patients experiencing pain during sexual activity, yet these concerns are often overlooked in neurosurgical care plans.*
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The Impact of Fertility Goals on Long-term Quality of Life in Reproductive-aged Women Who Underwent Myomectomy versus Hysterectomy for Uterine Fibroids.

J Minim Invasive Gynecol

August 2023

ObGyn and Women's Health Institute (Drs. Frisch, Llarena, Omosigho, Bradley, and Falcone); and Quantitative Health Sciences (Mr. Yao), Cleveland Clinic Foundation, Cleveland, Ohio; Cleveland Clinic Lerner School of Medicine, Cleveland, Ohio (Mr. Mitchell, Ms. DeAngelo, and Ms. Arakelian); HRC Fertility, Pasadena, California (Dr. Llarena).

Study Objective: The objective of this study is to compare quality of life (QOL) for myomectomy with hysterectomy 1 to 5 years after surgical management for fibroids. This study evaluated the difference in QOL in a population of women of reproductive age, including those who desire fertility.

Design: A retrospective cohort study.

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Background: Virtual visits have the potential to decrease barriers to prenatal care stemming from transportation, work, and childcare concerns. However, data regarding patient experience and satisfaction with virtual visits remain limited in obstetrics. To address this gap, we explore average-risk pregnant women's experiences with virtual visits and compare satisfaction with virtual vs.

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Variation as Evidence of Preventability: Research and Policy Implications of State Differences in Severe Maternal Morbidity Rates.

Obstet Gynecol

May 2023

Adina R. Kern-Goldberger is from the Division of Maternal-Fetal Medicine, Women's Health Institute, Cleveland Clinic Foundation, and the Department of Quantitative Health Sciences, Cleveland Clinic Lerner Research Institute, Cleveland, Ohio. Sindhu K. Srinivas is from the Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; email: .

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Paternalism in practice: How we create obstacles for sexual, reproductive, and menopausal healthcare despite our best intentions.

Cleve Clin J Med

April 2023

Department of Subspecialty Women's Health, Ob/Gyn and Women's Health Institute, Cleveland Clinic, Cleveland, OH; Professor, Ob/Gyn and Reproductive Biology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH

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Background: As more transgender and gender-diverse patients undergo hysterectomy, gaps in knowledge remain about how testosterone dosing or other physiologic parameters change following surgery and how these are influenced by concomitant oophorectomy.

Aim: The aims of this study were to determine the incidence of testosterone dosing change after gender-affirming hysterectomy and to compare this incidence between patients who underwent oophorectomy and ovarian preservation.

Methods: This multicenter retrospective cohort study consisted of transmasculine patients who underwent hysterectomy for gender affirmation.

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Importance: Recurrent urinary tract infection (rUTI) poses a significant management challenge, and fecal microbiota transfer (FMT) has been shown in a limited manner to positively effect rUTI.

Objectives: The objective of this study was to compare UTI rates after FMT for Clostridium difficile infection (CDI) in patients with previously diagnosed rUTI and patients without a previous diagnosis of rUTI.

Study Design: This was a retrospective cohort study of female patients who underwent FMT between 2015 and 2020 and were identified from a database at a tertiary care referral center.

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Importance: Discharge to home after surgery has been recognized as a determinant of long-term survival and is a common concern in the elderly population.

Objective: The aim of the study was to determine the incidence and risk factors for nonhome discharge in patients undergoing major surgery for pelvic organ prolapse.

Study Design: We performed a retrospective cohort study using the American College of Surgeons National Surgical Quality Improvement Program Database from 2010 to 2018.

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Changes in sexual function over 12 months after native-tissue vaginal pelvic organ prolapse surgery with and without hysterectomy.

Sex Med

April 2023

Center for Urogynecology and Pelvic Reconstructive Surgery, Women's Health Institute, Cleveland Clinic, Cleveland, OH 44195, United States.

Background: There is a need to determine how preoperative sexual activity, uterine preservation, and hysterectomy affect sexual function after pelvic organ prolapse surgery.

Aim: (1) To determine changes in sexual function in women, stratified by preoperative sexual activity status, after native-tissue pelvic organ prolapse surgery. (2) To examine the impact of hysterectomy and uterine preservation on sexual function.

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Anatomical and Surgical Considerations for Ileocolic Endometriosis.

J Minim Invasive Gynecol

June 2023

Women's Health Institute, Division of Minimally Invasive Gynecologic Surgery (Drs. Carey-Love, Dassel, Russo).

Objective: We aim to review the incidence, location, and management of bowel endometriosis and demonstrate relevant surgical principles while emphasizing anatomic considerations for minimally invasive resection of ileocolic lesions.

Design: This video briefly reviews the background of bowel endometriosis and indications for surgical excision. We present a case of a patient diagnosed with symptomatic terminal ileum endometriosis and review the preoperative imaging.

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Introduction: Surgery trainees spend their prime fertility years in training, which leads to delays in childbearing, accompanying infertility challenges, and high-risk pregnancies. Literature report of institutional support for fertility preservation (egg/sperm freezing) and treatment is lacking. The cost is particularly prohibitive while receiving a resident physician salary.

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Objective: The Cervantes-GSM questionnaire is a novel tool currently being developed to examine the impact of genitourinary symptoms on health-related quality of life in adult women with genitourinary syndrome of menopause (GSM).

Methods: A literature review and cognitive debriefing were conducted in women with GSM, which provided the basis for creating a draft questionnaire. This draft version was pilot-tested to check participant comprehension and ease of completion.

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TRANSLACOL project: Nodal human papillomavirus tumoral DNA detection by ddPCR for survival prediction in early cervical cancer patients without pelvic lymph node invasion.

J Clin Virol

April 2023

Virology Laboratory, Hôpital européen Georges-Pompidou, APHP.Centre - Université Paris Cité, Paris, France; Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, Université de Paris, Functional Genomics of Solid Tumors laboratory, équipe labellisée Ligue Nationale contre le Cancer, Labex OncoImmunology, Paris, France; Université de Paris Cité, Faculté de Santé, UFR de Médecine, Paris, France. Electronic address:

Introduction: In early cervical cancer (EEC), 10 to 15% of patients without nodal metastasis (N-) will suffer from recurrences with further similar survival as N+ patients. However, no clinical, imaging or pathological risk-factor is today available to identify them. In the present study, we hypothesized that the N- histologically characterized patients who present a poor prognosis could be patients for whom metastasis are missed by classical procedure.

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Mechanistic Insights on Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer.

Cancers (Basel)

February 2023

Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44106, USA.

Epithelial ovarian cancer is an aggressive disease of the female reproductive system and a leading cause of cancer death in women. Standard of care includes surgery and platinum-based chemotherapy, yet patients continue to experience a high rate of recurrence and metastasis. Hyperthermic intraperitoneal chemotherapy (HIPEC) treatment in highly selective patients extends overall survival by nearly 12 months.

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Effect of contraceptive hormonal therapy on mammographic breast density: A longitudinal cohort study.

Clin Imaging

May 2023

Department of Obstetrics & Gynecology, Women's Health Institute, Cleveland Clinic, Desk A81, 9500 Euclid Avenue, Cleveland, OH 44195, United States.

Purpose: Evaluate the longitudinal relationship between mammographic density and hormonal contraceptive use in late reproductive-aged women.

Methods: Patients aged 35-50 years old who underwent 5 or more screening mammograms within a 7.5-year period between 2004 and 2019 in a single urban tertiary care center were randomly selected.

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Objective: Pentosan polysulfate (PPS; ELMIRON, Janssen Pharmaceuticals, Titusville, NJ) is a U.S. Food and Drug Administration-approved oral medication for interstitial cystitis.

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Women at risk for hereditary breast and ovarian cancer syndromes are frequently seen in primary care and gynecology clinics. They present with a distinctive set of clinical and emotional needs that revolve around complex risk management discussions and decision making. The care of these women calls for the creation of individualized care plans that facilitate adjustment to the mental and physical changes associated with their choices.

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Perforation During Gynecological Procedures.

JAMA

March 2023

Obstetrics and Gynecology and Women's Health Institute, Division of Reproductive Endocrinology and Infertility, Cleveland Clinic, Cleveland, Ohio.

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Update on current contraceptive options: A case-based discussion of efficacy, eligibility, and use.

Cleve Clin J Med

March 2023

Department of Subspecialty Care for Women's Health, Ob/Gyn and Women's Health Institute, Cleveland Clinic, Cleveland, OH; Professor, Ob/Gyn and Reproductive Biology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH; Deputy Editor, Cleveland Clinic Journal of Medicine

With high rates of unintended pregnancy in the United States, it is crucial for clinicians to be well-informed about the full spectrum of contraceptive options to improve reproductive autonomy. We review new contraceptive options including a nonhormonal intravaginal gel, hormonal contraceptives in the form of new pills, patches, and vaginal rings, and combined hormonal contraceptives that contain new estrogens as alternatives to ethinyl estradiol. We review updated prescribing methods for several established hormonal contraceptives such as depot medroxyprogesterone acetate, which is now available for subcutaneous self-injection.

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Article Synopsis
  • - The study addresses the challenge of distinguishing metastatic cervical cancer from new primary tumors in patients with a history of cervical cancer by utilizing HPV molecular genotyping tests.
  • - Researchers analyzed cases from 2010 to 2020 involving patients with cervical cancer and new lesions, employing a specific PCR method to detect high-risk HPV DNA in those lesions.
  • - The findings showed that in most cases, the presence of HPV DNA confirmed cervical cancer metastasis, while one case revealed no HPV, indicating a new primary lung cancer, thus demonstrating the potential efficacy of molecular genotyping in diagnosis.
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Life-limiting fetal conditions: Are Australian student midwives prepared? A mixed-methods survey.

Nurse Educ Pract

March 2023

School of Women's and Children's Health, UNSW Medicine, Level 1 Women's Health Institute Royal Hospital for Women, Barker Street, Randwick, NSW 2031, Australia; Department of Women's and Children's Health, St George Hospital, Gray Street, Kogarah, NSW 2217, Australia. Electronic address:

Aim: To document current teaching methods, curriculum, and perceived educational preparation related to the teaching of life-limiting fetal conditions, termination, and perinatal palliative care to Australian student midwives.

Background: Australian women receiving a diagnosis of a life-limiting fetal condition are generally offered a choice between termination of pregnancy and perinatal palliative care. Midwives are often involved with caring for these women.

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Standard quality criteria in retracted vs nonretracted obstetrical randomized controlled trials.

Am J Obstet Gynecol MFM

May 2023

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, PA (XX Berghella).

Article Synopsis
  • * The research compared retracted and nonretracted randomized controlled trials focusing on 7 quality metrics, finding significant differences in trial registration and overall quality adherence.
  • * Results indicated that retracted trials were considerably less likely to be prospectively registered and met fewer quality criteria, suggesting a potential screening method to predict article retraction based on these metrics.
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Intention matters: Success rate of bilateral salpingo-oophorectomy at the time of vaginal hysterectomy for pelvic organ prolapse.

Eur J Obstet Gynecol Reprod Biol

April 2023

Division of Female Urology, Pelvic Reconstructive Surgery & Voiding Dysfunction. Department of Urology, University of California Irvine, Irvine, CA, United States. Electronic address:

Objective: The objective of this study was to determine the incidence of successful bilateral salpingo-oophorectomy at the time of vaginal hysterectomy for pelvic organ prolapse and to evaluate associated factors and success rate over time.

Study Design: This was a retrospective chart review of all women who underwent vaginal hysterectomy for pelvic organ prolapse who were consented for bilateral salpingo-oophorectomy "if possible" and "including extraordinary measures" between 2014 and 2019 at a tertiary medical center. Baseline demographic data along with prolapse stage, operative findings, operative time, and complications were recorded.

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