Pediatric external auditory canal foreign bodies: a review of 698 cases.

Objective: The study goal was to determine the relationships between patient management factors and patient outcomes in pediatric patients with external auditory canal foreign bodies.

Study Design And Setting: Retrospective analysis was conducted of 698 consecutive cases of pediatric external auditory canal foreign bodies (n = 605 patients) who presented to a tertiary care pediatric referral center during a 6-year period.

Results: Emergency physicians frequently removed foreign bodies under direct visualization while otolaryngologists primarily used otomicroscopy.

An essential role for the substrate-binding region of Hsp40s in Saccharomyces cerevisiae.

In addition to regulating the ATPase cycle of Hsp70, a second critical role of Hsp40s has been proposed based on in vitro studies: binding to denatured protein substrates, followed by their presentation to Hsp70 for folding. However, the biological importance of this model is challenged by the fact that deletion of the substrate-binding domain of either of the two major Hsp40s of the yeast cytosol, Ydj1 and Sis1, leads to no severe defects, as long as regions necessary for Hsp70 interaction are retained. As an in vivo test of this model, requirements for viability were examined in a strain having deletions of both Hsp40 genes.

Clinical application of the two-layer (University of Wisconsin solution/perfluorochemical plus O2) method of pancreas preservation before transplantation.

Background: The two-layer method [University of Wisconson solution (UW)/perfluorochemical plus O2] for pancreas preservation has been demonstrated to be superior to simple UW storage alone in the canine model. For the first time, we applied the two-layer method to clinical whole-pancreas transplantation.

Methods: Pancreases were placed in the two-layer method in 10 cases and UW alone in 44 cases before transplant.

Coronary stent and over-the-wire catheter exchange using standard length guidewires: Jet exchange (JEX) practice and theory.

The practice and theoretical principles of hydraulic exchange of over-the-wire (OTW) stent and PTCA catheters are described. Seventy-eight Palmaz-Schatz coronary stent delivery systems (PS-SDS), 8 Cook Flex-stents, and 247 assorted OTW catheters were delivered and extracted over standard length coronary guidewires using Jet Exchange (JEX). JEX was performed by pressurizing the wire lumen of coronary stent catheters to 18-20 atm and PTCA catheters to 15 atm.

Origin and morphogenesis of neurons in the frog cardiac ganglion.

This paper reviews the cellular events underlying the formation of the cardiac ganglion in the frog. The first neurons become postmitotic at the end of embryogenesis and begin differentiating in a functioning heart. Neuronal precursors in the heart continue dividing and differenting at least through the beginning of metamorphosis.

Epidemiology of Viral Foodborne Disease.

Virus transmission via foods begins with fecal shedding of viruses by humans. Foodborne viruses infect perorally: These same agents have alterative fecal-oral routes, including person- to-person transmission and the water vehicle. No zoonotic viruses are transmitted via foods in North America.

The influence of an improved preservation solution on prognostic factors for graft survival in pediatric liver transplantation.

We investigated the influence of Eurocollins (EC) and University of Wisconson solution (UW) on prognostic factors for graft survival after pediatric liver transplantation. The 1-year graft survival was studied for 30 patients in which 38 transplantations were performed between 1982 and 1988. We preserved 19 grafts in EC and the other 19 grafts in UW solution.

Behavior of Aflatoxin M in Yogurt, Buttermilk and Kefir.

Yogurt, buttermilk and kefir were made from milk that was naturally contaminated with aflatoxin M (AFM). Yogurt was made from skim milk alone or skim milk supplemented with 4% nonfat dry milk. The AFM content of yogurt, regardless of formulation, appeared to vary during storage, but after 6 weeks at 7°C it was essentially at the same levels as in the initial milk.