7 results match your criteria: "William Beaumont Oakland University Medical School[Affiliation]"

This exploratory Phase 2 clinical trial is the first determining safety and efficacy of oral D-methionine (D-met) in reducing cisplatin-induced ototoxicity. Randomised parallel double-blind placebo-controlled exploratory Phase 2 study. Fifty adult cancer patients received oral D-met or placebo before each cisplatin dose.

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Background/purpose: Stratification of Gleason score (GS) into three categories (2-6, 7, and 8-10) may not fully utilize its prognostic discrimination, with Gleason pattern 5 (GP5) previously identified as an independent adverse factor.

Materials/methods: Patients treated on RTOG 9202 (n = 1292) or RTOG 9902 (n = 378) were pooled and assessed for association of GS and GP5 on biochemical failure (BF), local failure (LF), distant metastasis (DM), and overall survival (OS). Fine and Gray's regression and cumulative incidence methods were used for univariate and multivariate analyses.

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Importance: Optimizing radiation therapy techniques for localized prostate cancer can affect patient outcomes. Dose escalation improves biochemical control, but no prior trials were powered to detect overall survival (OS) differences.

Objective: To determine whether radiation dose escalation to 79.

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The authors reply.

Pediatr Crit Care Med

June 2015

Division of Pediatric Critical Care, Department of Pediatrics, University of Missouri, Kansas City/Children's Mercy Hospital, Kansas City, MO Division of Pediatric Critical Care, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX Division of Pediatric Critical Care, Department of Pediatrics, University of Missouri, Kansas City/Children's Mercy Hospital, Kansas City, MO Division of Pediatric Surgery, William Beaumont Oakland University Medical School, Royal Oak, MI Department of Critical Care Services, Children's Medical Center, Dallas, TX Section of Pediatric Critical Care, Department of Pediatrics, Baylor College of Medicine/Texas Children's Hospital, Houston, TX.

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Extubation during pediatric extracorporeal membrane oxygenation: a single-center experience.

Pediatr Crit Care Med

November 2014

1Department of Pediatrics, Division of Pediatric Critical Care, University of Texas Southwestern Medical Center, Dallas, TX. 2Department of Pediatrics, Division of Pediatric Critical Care, University of Missouri, Kansas City/Children's Mercy Hospital, Kansas City, MO. 3Division of Pediatric Surgery, William Beaumont Oakland University Medical School, Royal Oak, MI. 4Department of Critical Care Services, Children's Medical Center, Dallas, TX. 5Department of Pediatrics, Section of Pediatric Critical Care, Baylor College of Medicine/Texas Children's Hospital, Houston, TX.

Objectives: Describe aspects of one center's experience extubating infants and children during extracorporeal membrane oxygenation.

Design: Retrospective review of medical records.

Setting: Seventy-one-bed critical care service (PICU and cardiovascular ICU) in a large urban tertiary children's hospital.

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