Type 1 Diabetes Mellitus in Movies: The Hollywood Effect.

Introduction: Type 1 diabetes mellitus (T1D) is one of the most common chronic diseases with childhood onset. Cinematic films and movies can reach populations worldwide and affect their concept of this disease. Through this research, the authors examined the accuracy of movies depicting T1D from childhood into adulthood.

The impact of volatile anesthetics and propofol on phosphatidylinositol 4,5-bisphosphate signaling.

Phosphatidylinositol 4,5-bisphosphate (PIP), as well as other anionic phospholipids, play a pivotal role in various cellular processes, including ion channel regulation, receptor trafficking, and intracellular signaling pathways. The binding of volatile anesthetics and propofol to PIP leads to alterations in PIP-mediated signaling causing modulation of ion channels such as ɣ-aminobutyric acid type A (GABA) receptors, voltage-gated calcium channels, and potassium channels through various mechanisms. Additionally, the interaction between anionic phospholipids and G protein-coupled receptors plays a critical role in various anesthetic pathways, with these anesthetic-induced changes impacting PIP levels which cause cascading effects on receptor trafficking, including GABA receptor internalization.

In-Person Education During the Early COVID-19 Pandemic at Wichita Collegiate School.

Introduction: The COVID-19 pandemic forced most Kansas schools to adopt remote or hybrid learning in 2020-2021. Wichita Collegiate School proceeded with an in-person teaching model. The purpose of this study was to determine if in-person learning can be done safely during the COVID-19 pandemic prior to vaccine use.