37,536 results match your criteria: "West Indies; University of Queensland[Affiliation]"

Article Synopsis
  • * A total of five randomized controlled trials involving 347 patients were analyzed, showing that those receiving 5-HT3 antagonists had significantly lower rates of vomiting and nausea compared to the placebo group within the first 24 hours post-surgery.
  • * The results support the use of 5-HT3 antagonists in clinical settings to reduce PONV after neurosurgery, with evidence indicating better outcomes compared to placebo treatments.
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Introduction: This study explored the understanding and experiences related to health among Dominican American adolescents in an urban setting in the northeastern United States.

Method: A qualitative descriptive study was conducted, applying thematic analysis to focus group interview data from 23 students.

Results: Five themes emerged: (1) Health is All About Healthy Eating, (2) Sugarcoating, (3) Dynamics Affecting Adherence, (4) Dominican Cultural Influences on Health, and (5) Toll of the Immigrant Life.

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Article Synopsis
  • * The infection starts when cryptococcal spores, often found in bird droppings, are inhaled and can spread to the central nervous system, causing symptoms like headache and cognitive issues.
  • * The text also discusses a rare case of fulminant meningitis caused by both herpes simplex virus (HSV)-2 and cryptococcal infection, highlighting the increased mortality risk associated with cryptococcemia.
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Background: We compared racial and ethnic disparities in HIV diagnosis rates among adults in census tracts with the most disadvantaged vs. the most advantaged levels of social determinants of health.

Methods: In this ecologic analysis, we used the National HIV Surveillance System data from 2021 and social determinants of health data from 2017-2021 American Community Survey.

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Cancer Mortality among Hispanic Groups in the United States by Birthplace (2003-2017).

Cancer Epidemiol Biomarkers Prev

December 2024

Department of Epidemiology, Gillings School of Global Public Health, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Article Synopsis
  • The study examines cancer mortality rates among different Hispanic subgroups in the US over 15 years, focusing on variations based on nativity (native- or foreign-born).
  • Analysis of over 228,000 cancer deaths suggests that Puerto Rico-born, Cuba-born, and US-born Mexicans face some of the highest cancer mortality rates, with foreign-born Hispanics generally having higher rates than US-born, except Mexicans.
  • The findings highlight significant differences in cancer mortality by nativity within Hispanic populations, underscoring the need for tailored health resources to address these disparities.
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Initially, the Hartmann's procedure was done to reduce mortality in surgery cases of malignant rectal lesions, and not benign disease. However, the procedure was popularized in the management of perforated diverticular disease (PDD) in the 1970s. Herein, we present a case of a patient who had laparotomy and colostomy for PDD.

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Article Synopsis
  • Understanding how the immune system responds to SARS-CoV-2 is essential for developing effective treatments and understanding long-term immunity.
  • The study focused on measuring specific antibody responses (anti-RBD IgG) in unvaccinated individuals recovered from COVID-19 in Cuba, using ELISA methods to quantify antibody levels.
  • Findings indicated that those who experienced severe illness had significantly higher antibody levels and blocking abilities, while the antibody response generally declined over four months, showing that severity of disease is a key factor in the immune response.
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Craniomandibular variation in the endemic Hispaniolan primate, Antillothrix bernensis.

J Hum Evol

November 2024

NYCEP Morphometrics Group, USA; Center for Functional Anatomy and Evolution, Johns Hopkins University School of Medicine, 1830 East Monument St, 3rd Floor, Baltimore, MD 21287, USA.

Here we describe new fossil material of Antillothrix bernensis, a Pleistocene-Holocene primate taxon from Hispaniola. It is now represented by seven crania, five mandibles, and dozens of postcranial elements from several paleontologically rich cave systems. The five adult crania included here share a similar overall profile as well as specific features such as a deep depression at the glabella.

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Article Synopsis
  • Phthalate exposure is linked to adverse pregnancy outcomes, but the biological mechanisms behind these effects are not completely understood.
  • This study analyzed 99 pregnant women and 86 newborns from the PROTECT cohort, using advanced techniques to measure urinary phthalate levels and metabolic profiles in blood plasma.
  • Significant associations were found between specific phthalates and metabolic changes in maternal plasma, highlighting the need for more research on phthalate mixtures and their complex effects on both mother and fetus.
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A murine experimental model of the pulmonary thrombotic effect induced by the venom of the snake Bothrops lanceolatus.

PLoS Negl Trop Dis

October 2024

Instituto Clodomiro Picado, Facultad de Microbiología, Universidad de Costa Rica, San José, Costa Rica.

Article Synopsis
  • The venom of Bothrops lanceolatus, a viper species from Martinique, is known to cause thrombosis, particularly in patients bitten by juvenile snakes, prompting research into the underlying mechanisms.
  • The study compared the venoms of juvenile and adult specimens, revealing that juvenile venom induces more significant thrombus formation in mice than adult venom, despite both having similar proteomes.
  • An experimental model showcasing the thrombotic effects of B. lanceolatus venom was established, highlighting the differences in effects between juvenile and adult specimens, and indicating that other factors like metalloproteinase activity may not be solely responsible for thrombus formation.
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Background: Nursing homes in the Caribbean are scarce and the characteristics of their residents have not been previously documented. This study aimed to describe the clinical profiles of residents living in nursing homes in Guadeloupe and Martinique (French West Indies).

Methods: This is a cross-sectional study of the baseline screening data from the KASEHPAD (Karukera Study of Ageing in nursing homes) study.

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Challenges for eGFR equations in the developing world.

Curr Med Res Opin

November 2024

Department of Paraclinical Sciences, The University of the West Indies St Augustine Campus, St. Augustine, Trinidad and Tobago.

The populations in countries that have the highest number of individuals with chronic kidney disease (CKD) are the low and middle-income countries which are ethnically diverse. The regional and international data highlighting the need for continuous monitoring of renal function warrants that such countries use equations that give the best estimates of glomerular filtration rate for their settings. While chronic disease conditions such as diabetes and hypertension are the main conditions associated with CKD in adult populations and complicated urinary tract infections and congenital anomalies in the kidney and the urinary tract in the young, the management of patients with CKD at any age can be impacted by medical and non-biological factors.

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In 2010, Puerto Rico experienced a cluster of childhood lead poisoning cases stemming from parental occupational exposure to lead. Following the immediate response to this crisis, a dedicated coalition of pediatricians and public health practitioners sustained a collaborative effort to advance pediatric environmental health initiatives across Puerto Rico. Their commitment laid the groundwork for the establishment and evolution of Puerto Rico's comprehensive Childhood Lead Poisoning Prevention and Blood Lead Level Surveillance Program.

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Objective: Neuropsychological assessment of preschool children is essential for early detection of delays and referral for intervention prior to school entry. This is especially pertinent in low- and middle-income countries (LMICs), which are disproportionately impacted by micronutrient deficiencies and teratogenic exposures. The Grenada Learning and Memory Scale (GLAMS) was created for use in limited resource settings and includes a shopping list and face-name association test.

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Purpose: Lung cancer remains one of the leading causes of cancer-related mortality worldwide. It is the third cause of death among patients with cancer in Puerto Rico (PR) and non-small cell lung cancer (NSCLC) is the most prevalent. This study aims to describe the first-line treatment (1LT) and health care resource utilization (HCRU) among patients with NSCLC in PR.

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Article Synopsis
  • Parasites can adapt to exploit different host species, but little is known about their genetic evolution in natural settings with diverse hosts.
  • Researchers studied Bartonella bacteria in rodent populations in Israel to understand how they adapt when infecting different rodent species.
  • After infecting rodents, they found that specific genetic mutations dominated, particularly in a gene related to adhesion, indicating that these mutations could help the bacteria escape immune responses and evolve to better target specific hosts.
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Follicular thyroid carcinoma in an inbred family of mongrel dogs in Trinidad & Tobago.

J Vet Diagn Invest

November 2024

Department of Basic Veterinary Sciences, School of Veterinary Medicine, Faculty of Medical Sciences, University of the West Indies, Champs Fleurs, Trinidad and Tobago.

Thyroid tumors occur in many domestic species, but are most common in the dog, in which they are classified as follicular or medullary. During 2012-2016, we received tissue specimens or whole carcasses of 4 dogs with variable enlargement of the thyroid glands. The 2 males and 2 females were of mixed (mongrel) inbreeding, 3-4.

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Article Synopsis
  • The study reevaluates the fern genus Pecluma, revealing it may not be monophyletic due to the inclusion of several Polypodium species.
  • Using a genome-skimming method and fossil analysis, researchers establish Pecluma's phylogenetic position and suggest its biogeographic history originated in Eocene South America with later expansions to Central America and the West Indies.
  • The findings support the establishment of three new species combinations under Pecluma, indicating a stable generic composition in the Greater Antilles since the Miocene.
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Background: is a useful multipurpose tree species for agroforestry systems, but traditional seeded cultivars often become weedy and invasive. A seedless hybrid cultivar, 'KX4-Hawaii', offers a potential solution to this problem. However, relevant agronomic information and information on the performance of 'KX4-Hawaii' under varying growth conditions is required.

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Heart failure (HF) is a leading cause of hospitalizations in Haiti. However, few patients return for outpatient care. The factors contributing to chronic HF care access are poorly understood.

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Household water treatment (HWT) is recommended when safe drinking water is limited. To understand determinants of HWT adoption, we conducted a cross-sectional survey with 650 households across different regions in Haiti. Data were collected on 71 demographic and psychosocial factors and 2 outcomes (self-reported and confirmed HWT use).

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The Impact of Climate on Human Dengue Infections in the Caribbean.

Pathogens

September 2024

Department of Economics, The University of the West Indies, Cave Hill Campus, Cave Hill, Bridgetown BB11000, Barbados.

Climate change is no longer a hypothetical problem in the Caribbean but a new reality to which regional public health systems must adapt. One of its significant impacts is the increased transmission of infectious diseases, such as dengue fever, which is endemic in the region, and the presence of the mosquito vector responsible for transmitting the disease. (1) Methods: To assess the association between climatic factors and human dengue virus infections in the Caribbean, we conducted a systematic review of published studies on MEDLINE and Web of Science databases according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) criteria.

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We used whole genome sequencing (WGS) as an epidemiologic surveillance tool to elucidate the transmission dynamics of Shiga toxin-producing (STEC) strains along the beef production chain in South Africa. Isolates were obtained from a cattle farm, abattoirs and retail outlets. Isolates were analysed using WGS on a MiSeq platform (Illumina, San Diego, CA, USA) and phylogenetic analysis was carried out.

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Background: Studies evaluating the effects of natural disasters on cancer outcomes are scarce, especially among USA ethnic minority groups, and none have focused on the effects of concurrent natural disasters and the COVID-19 pandemic. The goal of this secondary data analysis is to explore the impact of concurrent exposure to COVID-19 and earthquakes on psychological distress and symptom burden among Puerto Rican cancer survivors.

Methods: This secondary data analysis ( = 101) was part of a longitudinal case-control cohort study ( = 402) aimed at describing unmet psychological needs among Puerto Rican cancer patients and non-cancer subjects previously exposed to Hurricane María in 2017.

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