Liver Function-Related Indicators and Risk of Gallstone Diseases-A Multicenter Study and a Systematic Review and Meta-Analysis.

We aim to examine the association between liver function-related indicators and gallstone disease (GSD) risk. The subjects who participated in the China Multicenter Physical Examination Cohort (CMPEC) were enrolled. Relative odds ratios (ORs) with 95% CIs and standardized mean differences (SMDs) were applied to investigate the effect of liver function-related indicators and GSD risk.

Health, economic, and social implications of COVID-19 for China's rural population.

This study examines the effects of local and nationwide COVID-19 disease control measures on the health and economy of China's rural population. We conducted phone surveys with 726 randomly selected village informants across seven rural Chinese provinces in February 2020. Four villages (0.

3D MR Elastography of Hepatocellular Carcinomas as a Potential Biomarker for Predicting Tumor Recurrence.

Background: Preoperative prediction of tumor recurrence is important in the management of patients with hepatocellular carcinoma (HCC).

Purpose: To investigate whether tumor stiffness derived by magnetic resonance elastography (MRE) could predict early recurrence of HCC after hepatic resection.

Study Type: Retrospective.

[The prevalence and related factors of HBV infection among adults in Mianyang].

To analyze the prevalence and related factors of HBV infection among people aged 18 years old and above in Mianyang city. A total of 260 950 residents, living in Mianyang city more than 6 months, aging 18 years old and above were employed by multi-stage random sampling method from November 2014 to September 2015. Questionnaire survey was conducted on participants using a self-designed questionnaire, including general demographic characteristics, family history of Hepatitis B, history of Hepatitis B vaccination and history of present illness, etc.

[Compliancy of pre-exposure prophylaxis for HIV infection in men who have sex with men in Chengdu].

To evaluate the compliancy of HIV pre-exposure prophylaxis (PrEP) in men who have sex with men (MSM) in Chengdu, Sichuan province, and explore the influencing factors. From 1 July 2013 to 30 September 2015, a random, open, multi-center and parallel control intervention study was conducted in 328 MSM enrolled by non-probability sampling in Chengdu. The MSM were divided into 3 groups randomly, i.

[Comparison of embryotoxicity of di(2-ethylhexyl) phthalate using mouse and human embryonic stem cell test models in vitro].

Objective: To establish a mouse embryonic stem cell test (mEST) model and human embryonic stem cell test (hEST) model, to evaluate the embryotoxicity of di(2-ethylhexyl) phthalate (DEHP).

Methods: We developed mEST and hEST models according to the European Centre for the Validation of Alternative METHODS (ECVAM). We used penicillin G (PN-G) as the standard negative reference and 5-fluorouracil (5-FU) as the standard positive reference, respectively, to verify validity of the models.

[Trendency analysis of infant mortality rate due to premature birth or low birth weight in China from 1996 to 2013].

Objective: To study the secular trend and characteristics of infant mortality rate due to premature birth or low birth weight (IMRPL) in China from 1996 to 2013.

Methods: Data used in this study was collected from the population-based Child's Health Surveillance Network of China. The Cochran-Armitage Trend test and Poisson regression were used to test the trend of IMRPL and explore the differences of the trend among different regions or areas.

[Effects of bisphenol A on testis testosterone synthesis in mouse cultured in vitro].

Objective: To investigate the effects of BPA on testosterone synthesis and the related genes expression in the fetal testis of male mouse by organ culture in vitro.

Methods: The testis tissues cultured in vitro were randomly divided into five groups, DMSO control group and 4 different concentration of BPA groups (10(-7), 10(-6), 10(-5) and 10(-4) mol/L respectively). The culture medium and gas were changed every 24 h.

Vanadium exposure-induced neurobehavioral alterations among Chinese workers.

Vanadium-containing products are manufactured and widely used in the modern industry. Yet the neurobehavioral toxicity due to occupational exposure to vanadium remained elusive. This cross-sectional study was designed to examine the neurotoxic effects of occupational vanadium exposure.

TNF-α and IL-1RA polymorphisms and silicosis susceptibility in Chinese workers exposed to silica particles: a case-control study.

Objective: To assess the association of TNF-α and IL-1RA SNPs with the risk of silicosis in Chinese workers exposed to silica particles.

Methods: Case-control study design was used to enroll 68 silicotic patients induced by silica particles and 68 healthy workers matched for length of silica particle exposure as controls. Both cases and controls were from the same company in southwest China, and each of them was requested to complete a questionnaire.

[Effects of DNA polymerase beta on certain genotoxicity of mouse fibroblast cell induced by hydroquinone].

Objective: To explore the effect of DNA polymerase beta (pol beta) expression level on genotoxicity in mouse fibroblast cell induced by hydroquinone (HQ).

Methods: pol beta wild-type cells (pol beta +/+), pol beta null cells (pol beta -/-) and pol beta overexpressed cells (pol beta oe) were applied as a model cell system. At various concentration of HQ, the cell cytotoxicities were detected by MTT assay.

An agent-based model for control strategies of Echinococcus granulosus.

Cystic echinococcosis is a widespread zoonosis, caused by Echinococcus granulosus. The definitive hosts are carnivores and the intermediate hosts are grazing animals. Because humans are often accidentally infected with the cystic stage of the parasite, a control program is being developed for Western China.

The effects of phytosterols/stanols on blood lipid profiles: a systematic review with meta-analysis.

The objective of this work is to conduct a systematic review that investigates the efficacy of phytosterols/stanols in lowering lipid concentration in individuals with non-familial hypercholesterolemia. Randomized controlled intervention trials were identified through selected international journal databases and reference lists of relevant publications. Two researchers extracted data from each identified trial and only trials of sufficient quality were included in the review.