Recreational Facilities as Reservoirs for Multidrug-Resistant Staphylococcus aureus.

Antibiotic-resistant pathogens in public settings present a growing risk to human health. Staphylococcus aureus often asymptomatically colonizes human skin, while virulent strains cause soft tissue infections, osteomyelitis, endocarditis, and are associated with cystic fibrosis. Here we investigated the presence and distribution of multidrug-resistant S.

β-Cell Secretory Capacity Predicts Metabolic Outcomes over 6 Years following Human Islet Transplantation.

Transplanted islet functional β-cell mass is measured by the β-cell secretory capacity derived from the acute insulin response to glucose-potentiated arginine (AIRpot), however, data are limited beyond one-year post-transplant for individuals with type 1 diabetes. We evaluated changes in β-cell secretory capacity in a single-center longitudinal analysis and examined relationships with measures of islet cell hormone metabolism and clinical measures of graft function (mixed-meal tolerance test [MMTT] C-peptide, BETA-2 score, and continuous glucose monitoring [CGM]). Eleven individuals received purified human pancreatic islets over one or two intra-portal infusions to achieve insulin-independence and were followed over a median (IQR) 6 (5-7) years.

Using and Modifying Standardized Restorative Treatments in Aphasia: Clinician Perspectives.

Purpose: Aphasia treatment should be individualized, so clinicians are likely modifying established treatment paradigms to fit client needs. Little extant research describes which treatment protocols clinicians modify, how and why they modify their treatments, and what sources they use to guide their modifications. The purpose of this study was to gain insights into these issues.

Selective fluorescence sensors for Cu and Hg ions using acridinium-polymer complexes.

The photophysical properties of two acridinium derivatives, 9-phenyl-10-methylacridinium (Ph-Arc) and 9-mesityl-10-methyl acridinium (Mes-Acr) were investigated in aqueous solutions of poly(methacrylic acids) (PMAA) at various pH values with various polymer to dye (R/D) ratios. In acidic conditions, PMAA effectively turned on the emission of both acridinium derivatives. Micromolar concentrations of copper (II) ions can selectively turn off the emission of dye/PMAA mixtures with a linear response range from 0.

The Mindful Brain: A Systematic Review of the Neural Correlates of Trait Mindfulness.

Trait self-report mindfulness scales measure one's disposition to pay nonjudgmental attention to the present moment. Concerns have been raised about the validity of trait mindfulness scales. Despite this, there is extensive literature correlating mindfulness scales with objective brain measures, with the goal of providing insight into mechanisms of mindfulness, and insight into associated positive mental health outcomes.

Connecting Auditory-Perceptual Prompts Used in Voice Therapy to Anatomy and Physiology: Application to the Estill Voice Model and the Rehabilitation Treatment Specification System.

Purpose: This clinical tutorial will present the concept of applying auditory-perceptual prompts (implicit instruction) typically used in voice therapy to the anatomy and physiology of the voice production system (explicit instruction) via the Estill Voice Model (EVM) and the Rehabilitation Treatment Specification System (RTSS).

Methods: EVM offers an integrated implicit-explicit instructional approach to voice training allowing for isolated practice of vocal structures (explicit) that interact to produce functional voice qualities (implicit), such as modal speech and louder projected voice qualities. In EVM, voice quality is correlated with the specific anatomy and physiologic adjustments via 13 Estill Figures and Options (eg, Larynx Figure has three options: High, Mid, and Low).

Double-shelled, rattle-architecture covalent organic framework: harnessing morphological manipulation for enhanced synergistic multi-drug chemo-photothermal cancer therapy.

Morphological modulation in covalent organic frameworks (COFs) with particular emphasis on the correlation between structure and target applications in biomedical fields, is currently in its early stage of evolution. Herein, a multifunctional rattle-architecture imine-based COF with a mobile core of gold nanoparticles (Au NPs) and an outer polydopamine (PDA) shell, tailored for cancer treatment, has been developed to effectively integrate dual responsive release capabilities with the potential for multiple therapeutic applications. The engineered COF displays outstanding crystallinity, a suitable size and precisely controlled morphological characteristics.

Present but Ignored: Physical Condition and Health-Related Quality of Life in College-Aged Females with Generalized Joint Hypermobility.

Background: Generalized joint hypermobility (GJH) is prevalent among young adults, necessitating effective monitoring of musculoskeletal health, particularly among college-aged females. This study aimed to identify physical fitness and health-related quality of life (HR-QoL) characteristics associated with GJH.

Methods: A total of 67 participants were assessed: 26 with GJH (mean age 20.

"Nobody does checkups back there": A qualitative study of refugees' healthcare needs in the United States from stakeholders' perspectives.

The number of refugees globally grew to 35.3 million in 2022, and many refugees are exposed to various health risks along their migration journey. As a result, they may arrive in host communities with numerous health issues, including communicable diseases and chronic and mental health conditions.

Environmental Suppression Mediates the Relationship Between Posttraumatic Stress and Cannabis Use Among Trauma-Exposed College Students.

Objective: Trauma exposure and posttraumatic stress (PTS) are prominent risk factors for problematic substance use, but little research has evaluated the mechanisms that link PTS and substance use. Emerging research supports the utility of reward probability (i.e.

Effect of telemonitoring and as-needed patient support on positive airway pressure therapy adherence.

Background: Obstructive sleep apnea (OSA) affects patient health and public welfare. Positive airway pressure (PAP) therapy is the preferred treatment of OSA, but therapy adherence rates remain suboptimal. Current literature demonstrates telemonitoring interventions to support improved PAP therapy adherence.

The BIORES-21 Survey: Insights Into Remote and Online Education in Biomechanics and Mechanobiology.

The COVID-19 pandemic necessitated mainstream adoption of online and remote learning approaches, which were highly advantageous yet challenging in many ways. The online modality, while teaching biomedical engineering-related topics in the areas of biomechanics, mechanobiology, and biomedical sciences, further added to the complexity faced by the faculty and students. Both the benefits and the challenges have not been explored systematically by juxtaposing experiences and reflections of both the faculty and students.

Using COVID-19 online learning modules to examine concerns of university students returning to in-person learning: a mixed-methods study.

Objective: Understand student concerns with returning to in-person instruction during the COVID-19 pandemic using an e-learning module.

Participants: 925 undergraduate and graduate students returning to in-person instruction in Fall 2021.

Methods: Five modules educated students about COVID and the transition to in-person learning and collected quantitative and qualitative data related to concerns about COVID and in-person learning.

Principles and procedures for revising the hierarchical taxonomy of psychopathology.

Quantitative, empirical approaches to establishing the structure of psychopathology hold promise to improve on traditional psychiatric classification systems. The Hierarchical Taxonomy of Psychopathology (HiTOP) is a framework that summarizes the substantial and growing body of quantitative evidence on the structure of psychopathology. To achieve its aims, HiTOP must incorporate emerging research in a systematic, ongoing fashion.

Measurement properties of Brief-BESTest scores from children, adolescents, and youth with visual impairments.

This study aimed to vet the measurement properties of Brief-BESTest scores in children, adolescents, and youth with visual impairment and blindness (YVI). A cross-sectional sample of YVI ( = 101) completed the Brief-BESTest, a modified version of the Y-Balance Test, the 360-degree turn test, bipedal quiet stance, and Activity-Specific Balance Confidence Scales. Thirty-seven YVI completed test-retest of the Brief-BESTest using a one-year interval.

Effects of an 8-Week Mindfulness Course in People With Voice Disorders.

Objectives: Nearly every modern textbook on the etiology and treatment of voice disorders (VD) recommends stress reduction for VD patients. The benefits of mindfulness for stress reduction are well documented, but published literature on mindfulness and VD is sparse. Our objective was to determine whether an 8-week mindfulness course could increase mindfulness and lower stress in people with VD, leading to a decrease in vocal handicap.

Testing the Effectiveness of a Community-Based Peer Support Intervention to Mitigate Social Isolation and Stigma of Adolescent Motherhood in Zimbabwe.

Objectives: Social isolation and stigma contribute to poor mental health outcomes. Adolescent mothers in Zimbabwe often experience isolation and stigma, lacking social support and resources to navigate motherhood. The study tested the effectiveness of a community-based peer support intervention to mitigate social isolation and stigma of adolescent motherhood in Harare, Zimbabwe.

Comprehension of indirect answers: Developmental trajectory for preschool- and early elementary school-aged children with typical development.

Indirect answers are a common type of non-literal language that do not provide an explicit "yes" or "no" to a question (e.g., "I have to work late" indirectly answered "Are you going to the party?" with a negative response).

Dietary intake and status of selenium in breast milk and serum of lactating mothers in Awka, South East Nigeria.

Selenium is an essential micronutrient for human growth and development. Breast milk is usually the primary source of this nutrient for infants which is fundamental for their healthy brain development; its deficiency can lead to severe neurocognitive outcomes. The concentration of selenium in breast milk is dependent on the maternal diet.