34 results match your criteria: "Wesleyan University Middletown[Affiliation]"

Bees and moths are globally important pollinators. Xeric barrens in the largely mesic northeastern USA support high levels of pollinator diversity, including rare bees and moths. We investigated the response of bee vs.

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During the COVID-19 pandemic, multiple groups faced increased risks for negative health and mortality. Using an intersectional framework, the current study explores how the global pandemic impacted lower-income women living in the United States through access to housing. Findings indicate several challenges  remaining stably housed during the pandemic.

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There has been a rapidly growing interest in the use of functionalized Au nanoparticles (NPs) as platforms in multiple applications in medicine and manufacturing. The sensing and targeting characteristics of these NPs, and the realization of precisely organized structures in manufacturing applications using such NPs, depend on the control of their surface functionalization. NP functionalization typically takes the form of polymer grafted layers, and a detailed knowledge of the chemical and structural properties of these layers is required to molecularly engineer the particle characteristics for specific applications.

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Ice loss in the Southern Hemisphere has been greatest over the past 30 years in West Antarctica. The high sensitivity of this region to climate change has motivated geologists to examine marine sedimentary records for evidence of past episodes of West Antarctic Ice Sheet (WAIS) instability. Sediments accumulating in the Scotia Sea are useful to examine for this purpose because they receive iceberg-rafted debris (IBRD) sourced from the Pacific- and Atlantic-facing sectors of West Antarctica.

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Article Synopsis
  • Breast carcinosarcoma is a rare and aggressive type of breast cancer, making up less than 1% of cases and having a poor prognosis due to its unique cell composition.
  • It typically lacks the common receptors found in other breast cancers, limiting treatment options.
  • This report details the case of a 56-year-old woman diagnosed with T2N1 stage carcinosarcoma and explores the treatment decisions made for her condition.
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Aim: Drastic changes in fire regimes are altering plant communities, inspiring ecologists to better understand the relationship between fire and plant species diversity. We examined the impact of a 90,000-ha wildfire on woody plant species diversity in an arid mountain range in southern Arizona, USA. We tested recent fire-diversity hypotheses by addressing the impacts on diversity of fire severity, fire variability, historical fire regimes, and topography.

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We use mass spectrometry (MS), under denaturing and non-denaturing solution conditions, along with ultraviolet photodissociation (UVPD) to characterize structural variations in New Delhi metallo-β-lactamase (NDM) upon perturbation by ligands or mutation. Mapping changes in the abundances and distributions of fragment ions enables sensitive detection of structural alterations throughout the protein. Binding of three covalent inhibitors was characterized: a pentafluorphenyl ester, an -aryloxycarbonyl hydroxamate, and ebselen.

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Associational effects-in which the vulnerability of a plant to herbivores is influenced by its neighbors-have been widely implicated in mediating plant-herbivore interactions. Studies of associational effects typically focus on interspecific interactions or pest-crop dynamics. However, associational effects may also be important for species with intraspecific variation in defensive traits.

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Negative frequency-dependent selection (NFDS) has been shown to maintain polymorphism in a diverse array of traits. The action of NFDS has been confirmed through modeling, experimental approaches, and genetic analyses. In this study, we investigated NFDS in the wild using morph-frequency changes spanning a 20-year period from over 30 dimorphic populations of .

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The enemy-free space hypothesis (EFSH) contends that generalist predators select for dietary specialization in insect herbivores. At a community level, the EFSH predicts that dietary specialization reduces predation risk, and this pattern has been found in several studies addressing the impact of individual predator taxa or guilds. However, predation at a community level is also subject to combinatorial effects of multiple-predator types, raising the question of how so-called multiple-predator effects relate to dietary specialization in insect herbivores.

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Our understanding of the long-term evolution of the Earth system is based on the assumption that terrestrial weathering rates should respond to, and hence help regulate, atmospheric CO and climate. Increased terrestrial weathering requires increased carbonate accumulation in marine sediments, which in turn is expected to result in a long-term deepening of the carbonate compensation depth (CCD). Here, we critically assess this long-term relationship between climate and carbon cycling.

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Equity in Action: Operationalizing Processes in State Governance.

J Law Med Ethics

June 2019

Susan Weisman, J.D., is a Senior Staff Attorney at the Public Health Law Center at Mitchell Hamline School of Law in St. Paul, Minnesota. She holds a BA from The Ohio State University (Columbus, OH) and a JD from Mitchell Hamline School of Law (St. Paul, MN). Karen Ben-Moshe, M.P.H., is the Senior Program Associate with the Public Health Institute, Health in All Policies program. She has a BA from Wesleyan University (Middletown, CT), an MPH from the UC Berkeley School of Public Health (Berkeley, CA), and an MPP from the UC Berkeley Goldman School of Public Policy (Berkeley, California). Vayong Moua, M.P.A., is a Health Equity Advocacy Director at Blue Cross and Blue Shield of Minnesota in Eagan, Minnesota. He received his BA from St. Olaf College (Northfield, MN) and his MPA from the Robert M. La Follette School of Public Affairs at the University of Wisconsin-Madison (Madison, WI). He is responsible for developing strategy and action for Blue Cross's prevention and health equity advocacy initiatives to reduce tobacco use, obesity, and health inequities. Sarah Hernandez, M.P.H., is the director of policy for the Office of Health Equity at the Colorado Department of Public Health and Environment. She has a BA from the University of Colorado (Denver, CO) and an MPH from the Colorado School of Public Health (Aurora, CO).

This article takes a birds-eye view of equity in action, showcasing efforts to embed an equity lens in legislated and non-legislated policies and practices in three states. Authors from California, Colorado, and Minnesota provide state-specific examples of how equity has been advanced and operationalized in state-level governance. The article describes progress and lessons learned and offers guidance to others.

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Article Synopsis
  • Scientists are studying a special fruit fly that has learned to survive on a toxic plant, and they want to understand the genetic changes that help it do that.
  • The plant contains a chemical called octanoic acid, which most fruit flies can't handle, but this one has developed a way to resist it.
  • By looking at the genes in these fruit flies, researchers found that some genes help the larvae resist the toxin, while others seem to only help the adult flies.
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Introduction: Resting-state connectivity patterns have been observed in humans and other mammal species, and can be recorded using a variety of different technologies. Functional connectivity has been previously compared between species using resting-state fMRI, but not in electrophysiological studies.

Methods: We compared connectivity with implanted electrodes in humans (electrocorticography) to macaques and sheep (microelectrocorticography), which are capable of recording neural data at high frequencies with spatial precision.

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Little is known about the natural history, biology, and population genetic structure of the Hardhead Silverside, a small schooling fish found around islands throughout the Caribbean. Our field observations of in the cays of Belize and the Florida Keys found that populations tend to be in close association with the shoreline in mangrove habitats. Due to this potential island-based population structuring, represents an ideal system to examine questions about gene flow and isolation by distance at different geographic scales.

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This paper presents a limited case study examining the causal inference of student mobility on standardized test performance, within one middle-class high school in suburban Connecticut. Administrative data were used from a district public high school enrolling 319 10th graders in 2010. Propensity score methods were used to estimate the causal effect of student mobility on Math, Science, Reading, and Writing portions of the Connecticut Academic Performance Test (CAPT), after matching mobile vs.

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Whither the "Improvement Standard"? Coverage for Severe Brain Injury after Jimmo v. Sebelius.

J Law Med Ethics

March 2016

Joseph J. Fins, M.D., M.A.C.P., is The E. William Davis, Jr. M.D. Professor of Medical Ethics and Chief of the Division of Medical Ethics at Weill Cornell Medical College where he is a Tenured Professor of Medicine, Professor of Medical Ethics in Neurology, Professor of Health Care Policy and Research, and Professor of Medicine in Psychiatry. He Co-Directs, the Consortium for the Advanced Study of Brain Injury (CASBI) at Weill Cornell and Rockefeller University, is a Senior Research Scholar in Law at the Yale Law School, an elected Member of the Institute of Medicine of the National Academy of Sciences, a Fellow of the American Academy of Arts and Sciences and an Academico de Honor (Honored Academic) of the Real Academia Nacional de Medicina de Espana (the Royal Academy of Medicine of Spain). He received his B.A. with Honors from Wesleyan University (Middletown, CT) and M.D. from Cornell University (New York, NY). Megan S. Wright, Ph.D., is a J.D. candidate (2016) at Yale Law School (New Haven, CT). She earned a Ph.D. in Sociology from the University of Arizona (Tucson, Arizona). Claudia Kraft is a third-year law student at Yale Law School (New Haven, CT). She received a B.A. in Human Biology from the University of Virginia (Charlottesville, VA). Alix Rogers, M.Phil., is concurrently pursuing a J.D. at Yale Law School (New Haven, CT), and a Ph.D. in the History and Philosophy of Science at the University of Cambridge (Cambridge, United Kingdom). She holds a M.Phil from the University of Cambridge (Cambridge, United Kingdom), and a B.A. from the University of Pennsylvania (Philadelphia, PA). Marina Romani is a J.D Candidate (2016) at Yale Law School (New Haven, CT). She received a B.S. in Biology from Dartmouth College (Hanover, NH). Samantha Godwin, J.D., is a Ph.D candidate and Gates Cambridge Scholar at Cambridge University and an LL.M student at Yale Law School. She received her B.A. and MA from University College London department of philosophy and her J.D. from

As improvements in neuroscience have enabled a better understanding of disorders of consciousness as well as methods to treat them, a hurdle that has become all too prevalent is the denial of coverage for treatment and rehabilitation services. In 2011, a settlement emerged from a Vermont District Court case, Jimmo v. Sebelius, which was brought to stop the use of an "improvement standard" that required tangible progress over an identifiable period of time for Medicare coverage of services.

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Recent studies of bacterial speciation have claimed to support the biological species concept-that reduced recombination is required for bacterial populations to diverge into species. This conclusion has been reached from the discovery that ecologically distinct clades show lower rates of recombination than that which occurs among closest relatives. However, these previous studies did not attempt to determine whether the more-rapidly recombining close relatives within the clades studied may also have diversified ecologically, without benefit of sexual isolation.

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Rhythmic Effects of Syntax Processing in Music and Language.

Front Psychol

December 2015

Music, Imaging, and Neural Dynamics Lab, Psychology and Neuroscience and Behavior, Wesleyan University Middletown, CT, USA.

Music and language are human cognitive and neural functions that share many structural similarities. Past theories posit a sharing of neural resources between syntax processing in music and language (Patel, 2003), and a dynamic attention network that governs general temporal processing (Large and Jones, 1999). Both make predictions about music and language processing over time.

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Genomes were obtained for three closely related strains of Synechococcus that are representative of putative ecotypes (PEs) that predominate at different depths in the 1 mm-thick, upper-green layer in the 60°C mat of Mushroom Spring, Yellowstone National Park, and exhibit different light adaptation and acclimation responses. The genomes were compared to the published genome of a previously obtained, closely related strain from a neighboring spring, and differences in both gene content and orthologous gene alleles between high-light-adapted and low-light-adapted strains were identified. Evidence of genetic differences that relate to adaptation to light intensity and/or quality, CO2uptake, nitrogen metabolism, organic carbon metabolism, and uptake of other nutrients were found between strains of the different putative ecotypes.

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Automatic processing of abstract musical tonality.

Front Hum Neurosci

December 2014

Center for Computational Neuroscience and Neural Technology, Boston University Boston, MA, USA ; Department of Biomedical Engineering, Boston University Boston, MA, USA.

Music perception builds on expectancy in harmony, melody, and rhythm. Neural responses to the violations of such expectations are observed in event-related potentials (ERPs) measured using electroencephalography. Most previous ERP studies demonstrating sensitivity to musical violations used stimuli that were temporally regular and musically structured, with less-frequent deviant events that differed from a specific expectation in some feature such as pitch, harmony, or rhythm.

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Assessment of MS/MS search algorithms with parent-protein profiling.

J Proteome Res

April 2014

Department of Biology and ‡Department of Mathematics and Computer Science, Wesleyan University Middletown Connecticut 06459, United States.

Peptide mass spectrometry relies crucially on algorithms that match peptides to spectra. We describe a method to evaluate the accuracy of these algorithms based on the masses of parent proteins before trypsin endoprotease digestion. Measurement of conformance to parent proteins provides a score for comparison of the performances of different algorithms as well as alternative parameter settings for a given algorithm.

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The future spread and impact of an introduced species will depend on how it adapts to the abiotic and biotic conditions encountered in its new range, so the potential for rapid evolution subsequent to species introduction is a critical, evolutionary dimension of invasion biology. Using a resurrection approach, we provide a direct test for change over time within populations in a species' introduced range, in the Asian shade annual Polygonum cespitosum. We document, over an 11-year period, the evolution of increased reproductive output as well as greater physiological and root-allocational plasticity in response to the more open, sunny conditions found in the North American range in which the species has become invasive.

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