8 results match your criteria: "Wenshan Sanqi Institute of Science and Technology[Affiliation]"

The roots of Salvia yunnanensis, an herbaceous perennial widely distributed in Southwest China, is often used as a substitute for S. miltiorrhiza, a highly valued plant in traditional Chinese medicine (Wu et al. 2014).

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Identification of Panax notoginseng origin using terahertz precision spectroscopy and neural network algorithm.

Talanta

July 2024

University of Shanghai for Science and Technology, Terahertz Technology Innovation Research Institute, Shanghai Key Lab of Modern Optical System, Shanghai Institute of Intelligent Science and Technology, Shanghai, 200093, China. Electronic address:

Panax notoginseng (P. notoginseng), a Chinese herb containing various saponins, benefits immune system in medicines development, which from Wenshan (authentic cultivation) is often counterfeited by others for large demand and limited supply. Here, we proposed a method for identifying P.

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Discovery of plant chemical defence mediated by a two-component system involving β-glucosidase in Panax species.

Nat Commun

January 2024

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.

Article Synopsis
  • Plants produce defense compounds in inactive forms and activate them during pathogen attacks, a strategy known as the two-component system.
  • Researchers discovered that the medicinal plant Panax notoginseng has a two-component defense system involving a chloroplast-localized enzyme (PnGH1) and protopanaxadiol ginsenosides, which are activated when the chloroplasts are damaged by pathogens.
  • This activation leads to the conversion of ginsenosides into more potent antifungal compounds, demonstrating a broader antifungal spectrum than the original compounds and suggesting potential applications for developing botanical pesticides in related Panax species.
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Panax notoginseng leaves (PNL) was considered as a promising functional food ingredient with abundant protopanaxdiol ginsenosides. In this study, the influence of different drying methods on chemical components in PNL was characterized by a newly developed heart-cutting 2D-LC-HRMS. Our data indicates that vigorous ginsenoside transformation occurs in PNL processed by sun-air drying and hot-air drying (HAD) at 50 °C, but not shade-air drying (SAD), HAD at 25 °C and steaming prior to drying (SD).

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Ginsenoside distribution in different architectural components of Panax notoginseng inflorescence and infructescence.

J Pharm Biomed Anal

September 2021

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China. Electronic address:

The roots of Panax notoginseng (Burk) F. H. Chen are used as a highly valuable Chinese herbal medicine in the prevention and treatment of cardiovascular and hematological diseases.

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Article Synopsis
  • Panax notoginseng is a traditional Chinese herb known for its valuable roots, primarily containing triterpenoid saponins as bioactive components that play a crucial role in medicinal uses.
  • Researchers combined advanced sequencing technologies to create a detailed transcriptome atlas, revealing new genes and alternative splicing events linked to ginsenoside biosynthesis, particularly in flowers rather than in leaves or roots.
  • The study found that roots of three-year-old plants are rich in specific saponins and showed a significant variation in ginsenoside content, contributing to the understanding of the herb's biosynthetic mechanisms.
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Preparative separation of minor saponins from leaves using biotransformation, macroporous resins, and preparative high-performance liquid chromatography.

J Ginseng Res

January 2019

State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Macao, China.

Background: Ginsenosides with less sugar moieties may exhibit the better adsorptive capacity and more pharmacological activities.

Methods: An efficient method for the separation of four minor saponins, including gypenoside XVII, notoginsenoside Fe, ginsenoside Rd2, and notoginsenoside Fd, from leaves (PNL) was established using biotransformation, macroporous resins, and subsequent preparative high-performance liquid chromatography.

Results: The dried PNL powder was immersed in the distilled water at 50°C for 30 min for converting the major saponins, ginsenosides Rb1, Rc, Rb2, and Rb3, to minor saponins, gypenoside XVII, notoginsenoside Fe, ginsenoside Rd2, and notoginsenoside Fd, respectively, by the enzymes present in PNL.

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Article Synopsis
  • The study focuses on developing analytical methods to accurately measure dammarane triterpene saponins in ginseng leaves (PNL), highlighting the use of UPLC/Q-TOF MS and HPLC-UV techniques.
  • The research optimized extraction conditions and found that ginsenosides Rc and Rb3 are converted to notoginsenosides Fe and Fd when in contact with water, indicating possible enzymatic processes.
  • A total of 57 saponins were identified, with 19 characterized, and the new HPLC-UV method showed high reliability for quantifying seven specific saponins, aiding in the quality control of PNL products.
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