Cartilage-bioinspired tenacious concrete-like hydrogel verified via in-situ testing.

Polyvinyl alcohol (PVA)/polyethylene glycol (PEG) hydrogels, being low-cost and abundant materials, can demonstrate tremendous potential in applications requiring mechanical robustness by harnessing the enhancements afforded by a structure inspired by articular cartilage (AC). This study presents the fabrication of bioinspired PVA/PEG (BPP) hydrogel, characterized by their high mechanical strength and low friction coefficient. By utilizing a concrete-like structure composed of PVA particles and PVA/PEG fibers, the BPP hydrogel demonstrates notable properties such as high compressive strength (86%, 29.

Modified chevron osteotomy for the treatment of hallux valgus with unison bioabsorbable screws: Biomechanical research and clinical applications.

Researchers have modified PLA materials to enhance their mechanical properties and meet the clinical requirements. However, the strength and stiffness of PLA are still significantly lower than those of metals. Building on the established chevron clinical procedure and considering the mechanical characteristics of PLA screws, we devised a modified chevron osteotomy (MCO) based on a load-reducing structure with the aim of reducing the load on the screws.

Association between systemic immune inflammation index and cataract incidence from 2005 to 2008.

The objective of this study is to investigate the association between the Systemic Immune-Inflammation Index (SII) and cataracts. This cross-sectional study analyzed data from the 2005-2008 NHANES to examine the relationship between the SII and cataract prevalence. Covariates included age, race/ethnicity, gender, education level, marital status, Body Mass Index (BMI), smoking, alcohol consumption, hypertension, hyperlipidemia, and diabetes.

Carboxymethylcellulose-based aggregation-induced emission antibacterial material for multifunctional applications.

Polysaccharides are ubiquitous in nature, typically harmless, and highly compatible with various tissues in biomedical contexts. These properties make them attractive for use in multifunctional materials. In this study, the aggregation-induced emission (AIE) antibacterial material (PLOCMC) was successfully synthesized by carboxymethylcellulose (CMC) and ε-Poly-Lysine (ε-PL).

Chitosan-based hydrogel dressings with antibacterial and antioxidant for wound healing.

Bacterial infection and free radical oxidative stress at the wound site could easily cause cascade inflammation and hinder the healing process of the wound. In this study, chitosan-cysteine-gallic acid (CCG) hydrogel with antibacterial and antioxidant properties was synthesized by chitosan (CS), cysteine (Cys), and gallic acid (GA) for a preliminary evaluation of its therapeutic efficacy in a mouse model of full-layer skin defect. In vitro analysis showed that the CCG hydrogel had good antibacterial activity and blood compatibility.

An Injectable Thermosensitive Hydrogel with Antibacterial and Antioxidation Properties for Accelerating Wound Healing.

As a new type of wound dressing, hydrogels have attracted more and more attention. However, traditional hydrogel wound dressings lack inherent antibacterial properties and are difficult to match irregular wounds, which leads to an easy wound bacterial infection. To solve the problems associated with traditional hydrogels, in this research, a thermosensitive hydrogel (PFLD) for wound dressings was developed based on Poloxamer 407 (PF127), lysine (Lys), and 3,4-dihydroxyphenylacetic acid (DOPAC).

Superwetting PVA/cellulose aerogel with asymmetric structure for oil/water separation and solar-driven seawater desalination.

Extracting clean water from oily wastewater and seawater is one of the effective strategies to alleviate the freshwater crisis. However, achieving both high separation efficiency and excellent salt resistance remain challenges for materials. Herein, a novel methyltrichlorosilane-modified polyvinyl alcohol/cellulose aerogel (MPCA) was prepared by freeze drying, chemical cross-linking, and chemical vapor deposition (CVD) methods.

Photocrosslinked carboxymethylcellulose-based hydrogels: Synthesis, characterization for curcumin delivery and wound healing.

Skin could protect our body and regenerate itself to against dysfunctional and disfiguring scars when faced with external injury. As wound dressings, hydrogels are biocompatible, hydrophilic and have a 3D structure similar to the extracellular matrix (ECM). In particular, hydrogels with drug-releasing capabilities are in acute wound healing.

Fe-induced coordination cross-linking gallic acid-carboxymethyl cellulose self-healing hydrogel.

Self-healing hydrogel is a promising soft material for applications in wound dressings, drug delivery, tissue engineering, biomimetic electronic skin, and wearable electronic devices. However, it is a challenge to fabricate the self-healing hydrogels without external stimuli. Inspired by mussel, the metal-catechol complexes were introduced into the hydrogel systems to prepare the mussel-inspired hydrogels by regulating the gelation kinetics of Fe crosslinkers with gallic acid (GA) in this research.

Fabrication of carboxymethyl cellulose-based thermo-sensitive hydrogels and inhibition of corneal neovascularization.

Corneal neovascularization (CNV) is a common multifactorial sequela of anterior corneal segment inflammation, which could lead to visual impairment and even blindness. The main treatments available are surgical sutures and invasive drug injections, which could cause serious ocular complications. To solve this problem, a thermo-sensitive drug-loaded hydrogel with high transparency was prepared in this study, which could achieve the sustained-release of drugs without affecting normal vision.

Bone morphogenetic protein 4 thermosensitive hydrogel inhibits corneal neovascularization by repairing corneal epithelial apical junctional complexes.

Corneal neovascularization (CNV) is a heavy attribute of blinding disease changes. Existing medications need numerous infusions and have a limited absorption. Investigating novel drugs with safety, efficacy, and convenience is crucial.

Multimodal and flexible hydrogel-based sensors for respiratory monitoring and posture recognition.

The accurate monitoring of respiratory events and human motion states holds paramount importance in the realm of health surveillance and disease prognostication. An exquisitely precise, multifaceted, portable, and environmentally resilient sensor designed for health monitoring would undeniably be of utmost desirability, despite its persisting as a formidable challenge. Here, we propose a breath monitoring and posture recognition system that utilizes hydrogel electrolytes based on polyvinyl alcohol, sodium alginate, and starch, suitable for supercapacitors and multimodal wearable sensors.

Golden section criterion to achieve droplet trampoline effect on metal-based superhydrophobic surface.

Clarifying the consecutive droplet rebound mechanisms can provide scientific inspirations to regulate dynamic wettability of superhydrophobic surface, which facilitates the practical applications on efficient heat control and active anti-icing. Generally, droplet rebound behaviors are directly affected by surface structure and Weber number. Here, we report a novel "golden section" design criterion to regulate the droplet rebound number determined by the structure spacing, subverting conventional knowledge.

Coupled Effect of Low Temperature and Electrolyte Immersion on the Tensile Properties of Separators in Lithium-Ion Batteries.

The performance degradation at low temperatures and frequent safety accidents have aggravated security risks and inhibited the long-term service of lithium-ion batteries (LIBs). As a key component of LIBs, the separator has a great impact on the performance and safety of the battery. In this study, tensile tests of two commercial polyolefin separators (Celgard 2325 and Celgard PE) are performed under low-temperature and immersion conditions.

10-hydroxycamptothecin-loaded starch-based microcapsules with the stepwise responsive release strategy for targeted controlled release.

Controlled and accurate drug release at the target site have been the focus of research. Especially in cancer therapy, economical, convenient and accurate delivery strategies could help to reduce the toxic effects of drugs on normal tissues and improve drug availability. In the study, glutathione (GSH)-responsive microcapsules (FA-RSMCs) were prepared by sonochemical method based on thiolated modified starch.

Shovel-loading cooperative control of loader under typical working conditions.

The difference in power demand and the driver's operation in various operation stages make the loader have the problem of low energy utilization. Changeable operating objects and drastically changing loads have exacerbated the difficulty of energy-saving research in different operating stages of loaders. Therefore, based on identifying the operation stage and analyzing the load characteristics under typical working conditions of the loader, this paper proposes a shovel-loading cooperative control strategy.

Chitosan-based mussel-inspired hydrogel for rapid self-healing and high adhesion of tissue adhesion and wound dressings.

The hydrogel wound dressing with self-healing and adhesive property can provide better protection to the wound and prolong the service life of the material. Inspired by mussels, a high-adhesion, injectable, self-healing and antibacterial hydrogel was designed in this study. The lysine (Lys) and the catechol compound 3,4-dihydroxyphenylacetic acid (DOPAC) were grafted onto chitosan (CS).

Stimulus-responsive starch-based nanocapsules for targeted delivery and antibacterial applications.

Polysaccharide materials have attracted a widespread interest in the biomedical materials field due to their non-toxic, biocompatible and biodegradable properties. In this research, starch was modified with chloroacetic acid, folic acid (FA) and thioglycolic acid and then starch-based nanocapsules loaded with curcumin (FA-RSNCs@CUR) were prepared by the convenient oxidation method. The nanocapsules were prepared with stable particle size distribution of 100 nm.

Full Regional Creep Displacement Map of Articular Cartilage Based on Nanoindentation Array.

The elucidation of the mechanisms underlying articular cartilage lesions poses a formidable challenge in the field of cartilage repair. Despite significant strides in cartilage mechanics research, the region-dependent creep properties of articular cartilage remain elusive. In this study, we employ depth-sensing indentation tests to experimentally determine the creep properties of four distinct regions of articular cartilage, thereby unveiling a region-dependent full map of creep parameters.

Underwater Oleophobic Electrospun Membrane with Spindle-Knotted Structured Fibers for Oil-in-Water Emulsion Separation.

The potential of spider silk as an intriguing biological prototype for collecting water from a humid environment has attracted wide attention, and various materials with suitable structures have been engineered. Here, inspired by this phenomenon, a kind of superwetting poly(vinylidene fluoride) (PVDF) membrane with spindle-knotted structured fibers was prepared by the electrospinning method followed by oxygen plasma etching treatment. The prepared membrane presented a satisfactory separation efficiency for various oil-in-water emulsions.

Low-Voltage Driven Ionic Polymer-Metal Composite Actuators: Structures, Materials, and Applications.

With the characteristics of low driving voltage, light weight, and flexibility, ionic polymer-metal composites (IPMCs) have attracted much attention as excellent candidates for artificial muscle materials in the fields of biomedical devices, flexible robots, and microelectromechanical systems. Under small voltage excitation, ions inside the IPMC proton exchange membrane migrate directionally, leading to differences in the expansion rate of the cathode and the anode, which in turn deform. This behavior is caused by the synergistic action of a three-layer structure consisting of an external electrode layer and an internal proton exchange membrane, but the electrode layer is more dominant in this process due to the migration and storage of ions.

Injectable chitosan-based self-healing supramolecular hydrogels with temperature and pH dual-responsivenesses.

In this study, a supramolecular hydrogel was fabricated with orotic acid (OA) modified chitosan (OACS) and 2,6-diaminopurine (DAP). The obtained OACS-DAP supramolecular hydrogels have dual responsiveness to temperature and pH. Phase transition experiments indicate this is a temperature-dependent thermoreversible supramolecular hydrogel.

Temperature-Shift-Induced Mechanical Property Evolution of Lithium-Ion Battery Separator Using Cyclic Nanoindentation.

The evolution of mechanical properties of separators affected by temperature shifts is imperative for the performance of the lithium-ion battery. The flexible film characteristics hinder the evaluation of the micromechanical properties of separators. In the present study, considering the susceptibility of separators to temperature fluctuations, the temperature distribution of the battery during the discharging process at subzero temperature is obtained.

Schiff Base Aggregation-Induced Emission Luminogens for Sensing Applications: A Review.

Fluorescence sensing can not only identify a target substrate qualitatively but also achieve the purpose of quantitative detection through the change of the fluorescence signal. It has the advantages of immense sensitivity, rapid response, and excellent selectivity. The proposed aggregation-induced emission (AIE) concept solves the problem of the fluorescence of traditional fluorescent molecules becoming weak or quenched in high concentration or aggregated state conditions.