265 results match your criteria: "Weihai Central Hospital[Affiliation]"

Background: Laparoscopic gastrectomy lacks hand-direct tactile sense and has a limited surgical field compared to laparotomy. Apart from textbook classification, there are anatomical variations in the gastric arteries. Laparoscopic gastrectomy presents technical difficulties and necessitates a more comprehensive comprehension of regional anatomy than open surgical procedures.

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Background: Sarcomatoid carcinoma of the small bowel is an exceedingly rare gastrointestinal tumor characterized by a biphasic cellular pattern of epithelioid and mesenchymal-like cells. Due to its rarity and non-specific clinical presentation, it is frequently misdiagnosed, and there is a lack of standardized management guidelines. We report a case of multiple sarcomatoid carcinoma of the small intestine, presenting initially with gastrointestinal perforation.

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Diabetic kidney disease (DKD) is a severe microvascular complication of diabetes associated with high mortality and disability rates. Inflammation has emerged as a key pathological mechanism in DKD, prompting interest in novel therapeutic approaches targeting inflammatory pathways. Interleukin-6 (IL-6), a well-established inflammatory cytokine known for mediating various inflammatory responses, has attracted great attention in the DKD field.

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Article Synopsis
  • Diabetic nephropathy (DN) is a common complication of diabetes, and Colquhounia Root Tablet (CRT) has shown potential therapeutic effects, although its mechanisms are not fully understood.
  • Using various databases, researchers identified 163 therapeutic targets of CRT related to DN and found key targets like STAT3 and IL6 through protein-protein interaction analysis.
  • The study highlighted the AGEs/RAGE signaling pathway as significant for CRT's effectiveness against DN and confirmed its protective effects on kidney cells via experimental treatments, although further studies are required to assess the safety and efficacy in real-life scenarios.
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Article Synopsis
  • A study was conducted to evaluate if enhanced recovery after surgery (ERAS) improves overall survival and disease-free survival for patients undergoing laparoscopic distal gastrectomy for gastric cancer compared to conventional care.
  • 527 patients participated in the multicenter trial, which assessed outcomes like complications, recovery time, and medical expenses, with a follow-up of about 42 months.
  • Results showed that ERAS patients had a significantly higher 3-year overall survival (86.56%) and disease-free survival (79.57%), and experienced fewer complications and shorter hospital stays than those receiving conventional care.
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Associations of advanced lung cancer inflammation index with all-cause and respiratory disease mortality in adults with asthma: NHANES, 1999-2018.

Sci Rep

November 2024

Center of Colon and Rectum, Qingdao Municipal Hospital, Qingdao University, No. 1 Jiaozhou Road, Qingdao, 266011, Shandong Province, China.

The Advanced Lung Cancer Inflammation Index (ALI) represents both the inflammatory and nutritional status of the host, but its link with mortality in asthma patients is uncertain. The purpose of this study was to look at the relationship between ALI levels and all-cause and respiratory disease mortality in asthmatic patients. We conducted our research using cohort data from the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2018.

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The article "Aldose reductase inhibitor Epalrestat alleviates high glucose-induced cardiomyocyte apoptosis via ROS" by X. Wang, F. Yu, W.

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Clinical Characteristics of Related Endogenous Endophthalmitis in China.

Risk Manag Healthc Policy

November 2024

Eye Center, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, 102218, People's Republic of China.

Purpose: To investigate the clinical characteristics and systemic risk factors of related endogenous endophthalmitis (KPREE) in China and explore the possible pathophysiological mechanisms.

Methods: This was a retrospective comparative study. All enrolled KPREE patients were followed up for at least 1 month to observe their clinical characteristics, unfavorable prognosis, and risk factors, and were compared with intraocular surgery-related postoperative endophthalmitis (ISRPE).

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This retrospective study aimed to investigate the clinical efficacy of single-channel percutaneous endoscopic nucleotomy combined with annulus fibrosus suturing for treating lumbar disc herniation (LDH). The study included 86 patients with LDH treated in our spinal department from August 2020 to January 2022. The suture group consisted of 26 males and 18 females, while the control group (nucleotomy alone) included 25 males and 17 females.

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Case report: Gastric metastasis of breast cancer.

Front Oncol

September 2024

Department of Gastrointestinal Surgery, Weihai Central Hospital, Weihai, China.

Article Synopsis
  • Breast cancer is the most common malignant tumor in women and can lead to complications like recurrence and metastasis, with gastric involvement being quite rare.
  • This text presents a case study of a woman who developed gastric metastasis ten years after her breast cancer surgery, highlighting how unusual this situation is.
  • The findings stress the importance of ongoing monitoring for breast cancer patients to enable early detection and treatment of metastasis, which can greatly affect survival rates.
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Background: The HALP score, comprising hemoglobin, albumin, lymphocyte, and platelet levels, serves as an indicator of both nutritional and inflammatory status. However, its correlation with all-cause and cause-specific mortality among cancer survivors remains unclear. Therefore, this study aims to investigate the relationship between HALP scores and mortality outcomes in this population.

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Article Synopsis
  • * A case study of a mid-30s woman highlights a 6-cm pelvic tumor identified via ultrasound (US) and MRI, leading to a hysterectomy that confirmed STUMP through immunohistochemical analysis.
  • * Key imaging features include a well-circumscribed lesion on US, strong signal intensity on T2-weighted and diffusion-weighted MRI, and the importance of early diagnosis for effective treatment management.
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Metastasis occurs in nearly 50% of cases of adult soft-tissue sarcoma (ASTS), leading to a dismal prognosis, with a 2-year survival rate of ~30%. Consequently, a prognostic model that incorporates metastatic characteristics may be instrumental in predicting survival time and in crafting optimal personalized therapeutic strategies for patients with ASTS. In the present study, a prognostic prediction model for ASTS was developed by examining genes that are differentially expressed between non-metastatic and metastatic patients in the Gene Expression Omnibus dataset.

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Clinical application of a modified wiltse approach in middle and lower thoracic vertebrae: a case-control study of thoracic fracture patients.

BMC Musculoskelet Disord

September 2024

Department of Orthopedics, Weihai Central Hospital, Qingdao University, No. 3 West of Mishan Road, Wendeng District, Shandong, 264499, China.

Background: The Wiltse approach has been extensively employed in thoracolumbar surgeries due to its minimal muscle damage. However, in the middle and lower thoracic spine, the conventional Wiltse approach necessitates the severance of the latissimus dorsi and trapezius muscles, potentially leading to muscular injury. Consequently, we propose a modified Wiltse approach for the middle and lower thoracic vertebrae, which may further mitigate muscular damage.

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Background And Aims: Despite advances in technology and techniques, the recurrence rate of persistent atrial fibrillation (AF) following catheter ablation remains high. The Shensong Yangxin (SSYX) capsule, a renowned traditional Chinese medicine formula, is used in the treatment of cardiac arrhythmias. This trial aimed to investigate whether the SSYX can improve clinical outcomes in patients who have undergone catheter ablation for persistent AF.

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Multiple sarcomatoid carcinomas in the small intestine with perforation: A case report and literature review.

Medicine (Baltimore)

May 2024

Department of Gastrointestinal Surgery, Weihai Central Hospital, Qingdao University, Weihai, China.

Article Synopsis
  • Sarcomatoid carcinoma of the small intestine is a rare and aggressive cancer that is often diagnosed late, leading to poor patient outcomes; this study presents a detailed case to improve understanding and treatment approaches.
  • A 61-year-old male experienced gastrointestinal symptoms and was initially misdiagnosed before the cancer was discovered through surgical removal of lesions, indicating diagnostic challenges.
  • Despite surgery and recovery, the patient succumbed to brain metastasis five months later, underscoring the need for early detection and better intervention strategies.
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Cerebral fat embolism with turbid urine as the initial sign.

Brain Inj

September 2024

Department of Radiology, Beijing Friendship Hospital, Capital Medical University, Beijing, China.

Background: Cerebral fat embolism (CFE) is a rare but potentially fatal complication that can occur after long bone fractures. It represents one subcategory of fat embolisms (FE). Diagnosing CFE can be challenging due to its variable and nonspecific clinical manifestations.

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Ectopic thyroid arises from abnormal development of thyroid primordial tissues as it migrates to the lower interstitium during the embryonic period, which can occur at various locations during the descent process. However, ectopic thyroid in the subdiaphragmatic area is extremely rare. In this case, we report a case of ectopic thyroid located in the hepatoduodenal ligament.

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