Classification of Scanning Errors of Digital Scans Recorded by Using Intraoral Scanners.

Objectives: The different scanning errors that can be caused by the operator handling an intraoral scanner (IOS) or the intraoral conditions of the patient being scanned have not been described. The purpose of this review was to describe and classify the scanning errors that can be identified in digital scans recorded by using IOSs.

Overview: The identification of scanning errors in an intraoral scan and understanding the cause of these scanning errors are fundamental procedures for successfully handling an IOS and integrating these digital data acquisition technologies in dental practices.

Efficacy of sodium hypochlorite and peracetic acid in reducing cross-contamination during washing of baby spinach at different water quality levels.

We evaluated the antimicrobial performance of sodium hypochlorite (NaOCl) and peracetic acid (PAA) during washing of baby spinach in water of varying levels of organic load, as measured by its chemical oxygen demand (COD). Escherichia coli TVS353 was spot inoculated onto one unwashed leaf. Sanitizers were added into water with preadjusted COD (300 or 2500 ppm) to achieve concentrations from 20 to 80 ppm.

Comparative Diagnostic Performance of Color Doppler Flow Imaging, MicroFlow Imaging and Contrast-enhanced Ultrasound in Solid Renal Tumors.

Rationale And Objectives: Accurate distinguish malignant from benign renal masses remains a challenge for radiologists. The purpose of this study was to evaluate the value of Color Doppler Flow Imaging (CDFI), MicroFlow Imaging (MFI) and Contrast-enhanced Ultrasound (CEUS) in diagnosing solid renal tumors.

Materials And Methods: A total of 291 patients with 300 solid renal tumors pathologically confirmed were retrospectively analyzed between January 2020 and December 2022.

Influence of edentulous areas on the accuracy of the maximum intercuspal position recorded by using different intraoral scanners or an artificial intelligence-based program.

Statement Of Problem: Intraoral scans can be articulated in maximum intercuspal position (MIP) by using an artificial intelligence (AI) based program; however, the impact of edentulous areas on the accuracy of the MIP located using this AI-based program is unknown.

Purpose: The purpose of this in vitro study was to assess the impact of edentulous areas (0, 1, 2, 3, and 4 posterior mandibular teeth) on the accuracy of the MIP located using 3 intraoral scanners (IOSs) and an AI-based program.

Material And Methods: Stone casts articulated in MIP in an articulator were digitized (T710).

Research on the PFAS release and migration behavior of multi-layer outdoor jacket fabrics.

Perfluoroalkyl and poly-fluoroalkyl substances (PFAS) release from textiles is a source of human exposure, but the mechanisms behind this release remain insufficiently studied. This research investigates the release and transport mechanisms of PFAS in outdoor jacket fabrics treated with a short side-chain fluorinated polymers (CF-SFPs) for durable water repellency (DWR). PA-based and PET-based fabrics were exposed to outdoor conditions and subjected to accelerated aging, followed by abrasion, washing, and drying experiments to simulate wear and degradation.

Clinical utility of quantitative ultrasonography parameters combined with serum cancer antigen 15‑3, human epidermal growth factor receptor 2 and soluble E‑cadherin in diagnosing mass‑type breast cancer.

Contrast-enhanced ultrasonography (CEUS), a newly developed imaging technique, holds certain value in differentiating benign from malignant tumors. Additionally, serum tumor markers also exhibit significant clinical importance in the diagnosis and monitoring of malignant tumors. Reports have indicated abnormal expression of HER-2, CA153 and sE-cad in breast cancer.

A patient with probable rare blood Group B(A) phenotype.

Karl Landsteiner discovered ABO blood group system in the early 20 century, but still, uncertainty remains in immunohematology while detection of ABO subgroups or weaker variants. The presence of weak subgroups in patient samples gives rise to the discrepancy in forward (cell) and reverse (serum) grouping. We here report a case of the B(A) phenotype in a patient who was diagnosed with chronic liver disease with acute pancreatitis, requiring packed red blood cells due to anemia.

Intratonsillar Immunotherapy: A Convenient and Effective Alternative to Subcutaneous Immunotherapy for Allergic Rhinitis.

Allergen-specific immunotherapy (AIT) is the only treatment that addresses the root cause of immunoglobulin E (IgE)-mediated allergies, but conventional methods face challenges with treatment duration, patient compliance, and adverse effects. In this study, we propose intratonsillar immunotherapy (ITIT) as a new effective and safer route for AIT. Prior to clinical trials, we analyzed tonsil samples from human subjects to assess immune responses, measuring interleukin-4 (IL-4), IL-21, total IgE (tIgE), and allergen-specific IgE concentrations using ELISA and BioIC.

Comprehensive Cellular Senescence Evaluation to Aid Targeted Therapies.

Drug resistance to a single agent is common in cancer-targeted therapies, and rational drug combinations are a promising approach to overcome this challenge. Many Food and Drug Administration-approved drugs can induce cellular senescence, which possesses unique vulnerabilities and molecular signatures. However, there is limited analysis on the effect of the combination of cellular-senescence-inducing drugs and targeted therapy drugs.

Biotinylated Viscosity Sensitive Cell Membrane Probe for Targeted Imaging and Precise Visualization of Tumor Cells and Tumors.

Cancer is a global health challenge that urgently requires more sensitive and effective cancer detection methods. Fluorescence imaging with small molecule fluorescent probes has shown great promise for cancer detection but most of the developed probes lack active tumor cell targeting, which makes them unable to selectively target tumors, thereby reducing the accuracy of in vivo tumor detection. Herein, we report a novel probe that combines a viscosity-sensitive and cell membrane targetable fluorescent group with biotin for targeted imaging and precise visualization of tumor cells and tumors.

Common intestinal parasitic infections in an improved water access, sanitation, and hygiene profile setting in North Jakarta, Indonesia.

Intestinal parasitic infections (IPIs), caused by helminths and/or protozoa, continue to be a significant public health concern in Indonesia. Water access, sanitation, and hygiene practices (WASH) are influential factors for IPIs, especially among children. The aim of this study was to investigate the association between WASH and IPIs among school-aged children.

Prevalence of Intestinal Parasites and Associated Factors Among Public Primary Second-Cycle Schoolchildren in Debre Markos Town, Northwest Ethiopia: A Cross-Sectional Study.

Background And Aims: Intestinal parasitic infection is a common disease that causes significant morbidity and mortality in developing countries, including Ethiopia. The burden of intestinal parasites is worse in schoolchildren, which leads to absenteeism from school, lower cognitive ability, affects academic performance, and causes malnutrition and anemia. While many studies have been reported, there is a paucity of published data in Debre Markos.

Recent Advances in Self-Powered Sensors Based on Ionic Hydrogels.

After years of research and development, flexible sensors are gradually evolving from the traditional "electronic" paradigm to the "ionic" dimension. Smart flexible sensors derived from the concept of ion transport are gradually emerging in the flexible electronics. In particular, ionic hydrogels have increasingly become the focus of research on flexible sensors as a result of their tunable conductivity, flexibility, biocompatibility, and self-healable capabilities.

Engineering Active Interfaces on the Surface of Porous Single-Crystalline TiO Monoliths for Enhanced Catalytic Activity and Stability.

The engineering design and construction of active interfaces represents a promising approach amidst numerous initiatives aimed at augmenting catalytic activity. Herein, we present a novel approach to incorporate interconnected pores within bulk single crystals for the synthesis of macroscopic porous single-crystalline rutile titanium oxide (R-TiO). The porous single crystal (PSC) R-TiO couples a nanocrystalline framework as the solid phase with pores as the fluid phase within its structure, providing unique advantages in localized structure construction and in the field of catalysis.

Transferrin Disassociates TCR from CD3 Signaling Apparatus to Promote Metastasis.

Immune recognition and activation by the peptide-laden major histocompatibility complex-T cell receptor (TCR)-CD3 complex is essential for anti-tumor immunity. Tumors may escape immune surveillance by dissembling the complex. Here, we report that transferrin, which is overexpressed in patients with liver metastasis, disassociates TCR from the CD3 signaling apparatus by targeting the constant domain (CD) of T cell receptor α (TCRα), consequently suppresses T cell activation, and inhibits anti-metastatic and anti-tumor immunity.

Recent Advances in Asymmetric Wettability Dressings for Wound Exudate Management.

The management of wound exudate is of vital importance for wound healing. Exudate accumulation around wound prolongs inflammation and hinders healing. Although traditional dressings can absorb wound exudate, they are unable to drain exudate in time, often resulting in a poor feature with wound healing.

Equivalent reduction of Escherichia coli by rinsing hands with cold and warm water.

Objective: Hand washing is considered an important public health intervention to reduce the burden of communicable diseases such as gastrointestinal and respiratory tract infections. Washbasins in public restrooms are often only equipped with cold water and it can be observed that people only rinse their hands briefly after using the toilet instead of washing them properly with soap. As there are no recommendations on the optimal water temperature for efficacy, we measured the efficacy of simple hand rinsing with cold (4°C) and warm (40°C) water for 10 and 20 seconds compared to the European Norm EN 1499 reference hand wash.

Study Design and Baseline Characteristics of ALIGN, a Randomized Controlled Study of Atrasentan in Patients With IgA Nephropathy.

Introduction: Endothelin A (ETA) receptor activation is a driver of proteinuria, kidney inflammation, and fibrosis in IgA nephropathy (IgAN). Atrasentan, a selective ETA receptor antagonist, has potential to reduce proteinuria and preserve kidney function in IgAN. ALIGN (NCT04573478) is a phase 3, randomized, double-blind, placebo-controlled clinical trial of atrasentan in patients with IgAN at high risk of kidney function loss.

Effect of free gingival graft dimension on postsurgical shrinkage in posterior implant placement: A prospective parallel cohort study.

Statement Of Problem: The impact of free gingival graft (FGG) dimensions on the postsurgical shrinkage of keratinized tissue width (KTW) and surface area in posterior implant sites is unclear. Standardized assessments of how graft dimensions influence KTW and surface area shrinkage rates over a 6-month period after FGG are lacking.

Purpose: The purpose of this prospective parallel cohort study was to examine the impact of the graft dimensions on the postsurgical shrinkage of KTW and surface area over a 6-month follow-up period after FGG in the posterior regions.

Multi-Cancer Early Detection Tests: State of the Art and Implications for Radiologists.

Multi-cancer early detection (MCED) tests are already being marketed as noninvasive, convenient opportunities to test for multiple cancer types with a single blood sample. The technology varies-involving detection of circulating tumor DNA, fragments of DNA, RNA, or proteins unique to each targeted cancer. The priorities and tradeoffs of reaching diagnostic resolution in the setting of possible false positives and negatives remain under active study.

Electrocatalytic CO Reduction in Acids: A Groundbreaking Approach to Converting CO into Fuels and Feedstocks.

The electrocatalytic carbon dioxide reduction reaction (CORR) at industrial-level current densities provides a sustainable approach to converting CO into value-added fuels and feedstocks using renewable electricity. However, the CORR conducted typically in alkaline and neutral electrolytes encounters some challenges due to the inevitable reaction between CO and OH ions, which undermines CO utilization and leads to poor operational stability. Acidic media present a viable alternative by reducing (bi)carbonate production, thereby enhancing the carbon efficiency and stability in CORR.

Pathogen delivery route impacts disease severity in experimental Mycoplasma ovipneumoniae infection of domestic lambs.

M. ovipneumoniae is a respiratory pathogen that can cause mild to moderate pneumonia and reduced productivity in domestic lambs. However, studies on both natural and experimental M.

Accuracy (trueness and precision) of 3-dimensional virtual patients: an in vitro investigation of different facial scanners and digital integration techniques.

Objectives: To investigate the influence of different facial scanners and integration approaches on the accuracy of virtual dental patients (VDPs).

Methods: Forty VDPs were generated using a head mannequin and two facial scanners: 1) an industrial scanner and 2) a smartphone scanner. For each scanner, two integration methods were applied: 1) integration by virtual facebow scan and 2) integration by nose-teeth scan.

Threats of zoonotic pathogens in food chain: Current status and gaps in India.

Background: Public health is seriously threatened by transmission of zoonotic infection through the food chain. Factors like increasing population, deforestation, high demand for animal protein, and trade of sub-clinically infected animals are the main causes of the spread of infections from asymptomatic animals to humans. Despite several national programs like (The Clean India Mission) prevention of open defecation and water, sanitation, and hygiene (WASH), the incidence of diarrhoeal diseases remains high in India.