119 results match your criteria: "Warts Nongenital"
Efficacy of Intralesional Candida Injection in the Treatment of Cutaneous Warts: A Systematic Review and Meta-Analysis.
Acta Derm Venereol
October 2024
Research Center of Big Data and Meta-analysis, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; Department of Dermatology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan; Department of Dermatology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Article Synopsis
Comparative Analysis of Intralesional Immunotherapy and Conventional Treatments for Non-Genital Warts: A Systematic Review and Network Meta-Analysis.
Dermatol Pract Concept
July 2024
Department of Family and Community Medicine and Medical Education, College of Medicine, Taibah University, Al-Madinah Al-Munawara, Saudi Arabia.
Article Synopsis
- Warts, caused by human papillomavirus, are categorized into genital and non-genital types; non-genital warts can lead to psychological issues despite often showing no symptoms.
- The study aimed to identify the most effective intralesional immunotherapy treatments using network meta-analysis to compare various options.
- Results revealed that needling, furosemide with digoxin, and PBP antigen stimulants significantly outperformed traditional treatments in both complete and overall response for non-genital warts, highlighting the need for further research to validate these findings.
Intralesional Quadrivalent Human Papilloma Virus Vaccine Versus Candida Antigen in the Treatment of Multiple Recalcitrant Non-Genital Warts.
Dermatol Pract Concept
April 2024
Dermatology and Venereology Department, Talkha Central Hospital, Dakahlia, Egypt.
Introduction: Warts are the most prevalent clinical manifestation of Human Papilloma Virus (HPV) infections, which vary in morphological pattern depending on the site of the body affected.
Objectives: To evaluate the safety and efficacy of intralesional quadrivalent HPV vaccine versus candida antigen in treatment of multiple recalcitrant non-genital warts.
Methods: A randomized-control clinical trial included 60 cases with multiple recalcitrant warts who were randomly distributed into three groups; Group I included 20 patients who received intralesional candida antigen at a dose of 0.
Verrulyse Methionine as Monotherapy in Children and Adolescents With Common Warts.
J Cutan Med Surg
May 2024
Pediatric Dermatology Unit, Schneider Children's Medical Center of Israel, Petah Tikva, Israel.
Article Synopsis
- Common cutaneous non-genital viral warts are a frequent skin condition in kids, leading to discomfort and requiring multiple visits for treatment.
- This study examined the effectiveness of oral Verrulyse Methionine (VM) as a standalone treatment for children and adolescents with persistent warts that did not respond to previous therapies.
- Of the 25 patients treated with VM, 56% showed significant improvement within 4 months, and this method was painless with no reported side effects, making it a viable alternative to painful local treatments.
Article Synopsis
- Cutaneous warts are a common reason for dermatologist visits, but complete clearance is rare, motivating the exploration of cidofovir, an antiviral effective against HPV.
- A literature review analyzed various case reports and studies involving 603 patients treated with cidofovir, resulting in a clearance rate of 55.2% and no recurrence noted within 2 to 36 months post-treatment.
- Although 17.4% of patients experienced local side effects, cidofovir shows promise as a safe and effective alternative for stubborn non-genital warts, highlighting the need for further clinical trials.
Integrative analysis of gene expression and DNA methylation to identify biomarkers of non-genital warts induced by low-risk human papillomaviruses infection.
Heliyon
May 2023
Department of Applied Biological Sciences, Jordan University of Science and Technology, Irbid, 22110, Jordan.
Article Synopsis
- Human papillomaviruses can alter the gene expression and DNA methylation of host cells, but there’s limited data on how low-risk HPV infection affects these processes in wart formation.
- This study analyzed gene expression and DNA methylation profiles of common warts using datasets from the GEO database, employing various bioinformatics tools to identify and annotate differentially expressed and methylated genes.
- A total of 276 genes were found to be differentially expressed/methylated, with over half being upregulated and hypermethylated; further analysis highlighted extracellular components and identified significant hub genes, marking this as the first comprehensive study on non-genital warts linked to low-risk HPV types.
The Efficacy of Cryotherapy and Zinc Gluconate in Management of Anogenital Warts: A Randomized Double-Blind, Split-Side, Placebo-Controlled Trial.
Skinmed
March 2023
Department of Dermatology, Afzalipour Hospital, Kerman University of Medical Sciences, Kerman, Iran;
Article Synopsis
- Anogenital warts are a common sexually transmitted infection, causing economic and psychological problems, and the effectiveness of oral zinc in their treatment is under investigation.
- A study with 50 patients compared oral zinc gluconate alongside cryotherapy to a placebo over two months, with follow-ups every two weeks to track wart reduction.
- Results showed significant wart reduction in both groups, but no noticeable difference between zinc and placebo; however, the zinc group had more gastrointestinal side effects, suggesting more research is needed to fully assess zinc's role in treatment.
Warts among Patients Visiting the Outpatient Department of Dermatology in a Tertiary Care Centre: A Descriptive Cross-sectional Study.
JNMA J Nepal Med Assoc
September 2022
Department of Dermatology, Nobel Medical College Teaching Hospital, Biratnagar, Morang, Nepal.
Article Synopsis
- Warts, caused by the human papillomavirus, are non-cancerous growths that can lead to discomfort and social anxiety, prompting the study to investigate their prevalence in dermatology outpatients.
- The research was a descriptive cross-sectional study done over a year, involving a detailed patient history to analyze the characteristics of their warts.
- Results showed that out of 4802 outpatients, 140 (2.92%) had warts, with 24 being genital and 116 non-genital, indicating a prevalence rate consistent with other studies in similar healthcare environments.
Evaluation of Sleep Quality in Patients With Genital and Non-Genital Cutaneous Warts: a Prospective Controlled Study.
Dermatol Pract Concept
November 2022
Department of Dermatology, University of Health Sciences, İstanbul Training and Research Hospital, İstanbul, Turkey.
Article Synopsis
- Diseases, like cutaneous warts, can negatively impact sleep quality, which in turn may influence the immune system and disease progression.
- A study evaluated the sleep quality of 138 patients with cutaneous warts using the Pittsburgh Sleep Quality Index (PSQI) and found significantly poorer sleep quality compared to healthy controls, especially in those with genital warts.
- The results suggest that assessing and managing sleep quality in patients with warts, particularly genital warts, could improve their overall quality of life and management of the disease.
Efficacy and safety of date palm leaf-based ointment for treatment of cutaneous warts: A pilot clinical trial.
Dermatol Ther
December 2022
Aras Pharmaceuticals Ltd., Tehran, Iran.
Article Synopsis
Destructive therapies for cutaneous warts: A review of the evidence.
Aust J Gen Pract
October 2022
BMedSci, MBBS, MPH, FACD, Dermatology Staff Specialist, Department of Dermatology, Westmead Hospital, Westmead, NSW.
Article Synopsis
- Non-genital warts, caused by the human papillomavirus, can lead to discomfort and social avoidance, prompting patients to seek various treatment options despite their potential to resolve on their own.
- A literature review of studies up to June 2021 identified 15 different therapies for warts, including salicylic acid, cryotherapy, and laser treatment, but only a few were rigorously tested in randomized controlled trials.
- Effective wart management requires considering the location of the wart, the scientific evidence for each treatment, and the possible negative effects, while also promoting good hygiene practices to prevent virus spread.
Intralesional immunotherapy for non-genital warts: A systematic review and meta-analysis.
Indian J Dermatol Venereol Leprol
December 2022
Departments of Dermatology, St. Vincent's Hospital, Paldal-gu, Suwon, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea.
Article Synopsis
- Intralesional immunotherapy has been found to be effective and safe for treating non-genital warts, though systematic studies were lacking until recently.
- A comprehensive analysis of 54 studies found a 60.6% complete response rate and a very low recurrence rate of 2.0%, with only mild adverse effects reported.
- Despite some variability among studies, intralesional immunotherapy is recommended for patients with multiple warts due to its promising efficacy and safety.
Relationship between α-genus human papillomavirus and non-genital seborrheic keratosis: Report of new cases and updated review.
J Cosmet Dermatol
January 2023
The Department of Dermatology and Allergology, University Hospital of Munich LMU, Munich, Germany.
Background: Seborrheic keratoses (SK) are the most common acquired benign tumor that affects middle-aged or older adults with great cosmetic concern. Clinical and histopathological similarities of SK and common warts have been addressed by investigating the possible presence of human papillomavirus (HPV) DNA in SK. Previous studies suggested the association between α-genus HPV and SK located on genital skin, whereas the causal relationship between α-HPV and non-genital SK remains controversial.
View Article and Find Full Text PDFTopical hydrogen peroxide solution 40% in treatment of plane wart.
J Cosmet Dermatol
October 2022
Dermatology, Venereology and Andrology Department, Damietta Faculty of Medicine, Al-Azhar University, New Damietta, Egypt.
Article Synopsis
- - The study evaluates the effectiveness and safety of a 40% hydrogen peroxide solution for treating plane warts, as there is no fully effective existing therapy.
- - In the study, 30 patients received treatment through four sessions, with applications spaced two weeks apart, followed by a three-month monitoring for recurrence.
- - Results showed that 90% of patients had complete wart clearance, with no recurrences noted after the follow-up, suggesting that 40% hydrogen peroxide could be a safe, effective, and inexpensive treatment option for plane warts.
Self-Precautions among Dermatologists Managing HPV-Related Infections: Awareness and Current Practice of Dermatologists Practicing in Saudi Arabia.
Skinmed
January 2022
Johns Hopkins Aramco Health Care, Dhahran, Saudi Arabia.
Article Synopsis
- Dermatologists in Saudi Arabia face potential exposure to human papilloma virus (HPV) during wart treatments, yet their safety precautions vary widely.
- An online survey collected responses from 228 dermatologists, revealing that liquid nitrogen and electrocautery are the most common treatments for warts, with high glove usage but inconsistent practices around masks and disinfection.
- Notably, 34.65% of respondents reported having an HPV infection, and among them, over half developed warts while practicing dermatology, highlighting the need for better standardization of safety protocols.
Airborne particulate concentration during non-thermal nano-pulse stimulation wart clearance is negligible compared to thermal modalities.
Lasers Surg Med
January 2022
Biology Group, Pulse Biosciences, Hayward, CA.
Article Synopsis
- * Using a Condensation Particle Counter, researchers measured airborne particles during four dermatologic procedures and found that NPS produced minimal particulate matter, especially during wart removal treatments.
- * Results indicated that NPS procedures produced negligible changes in airborne particulate concentration, suggesting a lower risk of viral transmission compared to traditional thermal methods, making NPS a safer option during the pandemic.
Safety and Efficacy of Nano-Pulse Stimulation Treatment of Non-Genital, Cutaneous Warts (Verrucae).
Lasers Surg Med
December 2021
Pulse Biosciences, 3957 Point Eden Way, Hayward, California, 94545.
Article Synopsis
- This study evaluates the effectiveness and safety of nano-pulse stimulation (NPS) technology for treating common verrucae (warts), using short bursts of electrical energy to target and kill cells while minimizing damage to surrounding areas.
- A total of 62 subjects participated, with 195 verrucae treated using the NPS system, showing that 75.3% of treated verrucae were completely cleared within 60 days, with 54% responding after just one treatment.
- The study concluded that NPS is a safe and effective method for removing cutaneous verrucae, with minimal side effects reported and no serious adverse events observed.
Laser therapy in cutaneous and genital warts: A review article.
Dermatol Ther
January 2021
Department of Dermatology, Kerman University of Medical Sciences, Kerman, Iran.
Article Synopsis
- Traditional wart treatments often require lengthy courses and can lead to high recurrence rates and side effects.
- This review analyzed 50 studies on various laser therapies for both genital and non-genital warts, focusing on different laser types (PDL, Nd:YAG, Er:YAG, CO2).
- While complete response rates varied by laser type, no significant differences in effectiveness or recurrence rates were found between laser therapy and conventional treatments, though combining laser therapy with other treatments may benefit certain patients.
The Quadrivalent Human Papillomavirus Vaccine in Recalcitrant Non-genital Warts: A Retrospective Study.
Ann Acad Med Singap
October 2020
National Skin Centre, Singapore.
Article Synopsis
- * Conducted at the National Skin Centre, the research involved 26 patients with persistent warts; those who completed the full vaccination regimen showed varying degrees of wart clearance, with a significant percentage achieving complete clearance.
- * Results indicate that the HPV vaccine could be a helpful addition to current treatments for resistant warts, as none of the patients experienced adverse reactions during the study.
Study of BCG Immunotherapy in the Management of Multiple, Extensive Non-Genital Cutaneous Common Warts.
Indian Dermatol Online J
September 2020
Department of Dermatology, SVS Medical College, Mahbubnagar, Telangana, India.
Article Synopsis
- Thirty patients aged 6 to 60 were treated with the BCG vaccine injected into their largest wart every three weeks for up to five sessions, with evaluations conducted at regular intervals.
- Results showed that most patients, especially those aged 5-14, responded positively, with 70% achieving complete wart clearance by the end of three months, indicating BCG vaccine therapy as a viable option for managing extensive wart cases.
Evaluation of intralesional Candida antigen in diabetic patients with multiple warts.
J Cosmet Dermatol
April 2021
Physiology Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
Article Synopsis
- Diabetic patients face increased risks when using traditional wart treatments, such as secondary infections and slow healing, making alternative therapies necessary.
- A study evaluated the effectiveness of intralesional Candida antigen injections in 50 diabetic patients with multiple warts, comparing results with a control group receiving saline injections.
- Results showed that 80% of patients treated with Candida antigen achieved complete wart clearance, significantly higher than only 15% in the control group, suggesting this method is both effective and safe, despite some mild side effects.
Genome-wide identification of methylated CpG sites in nongenital cutaneous warts.
BMC Med Genomics
July 2020
Department of Internal Medicine, Jordan University of Science and Technology, Irbid, 22110, Jordan.
Article Synopsis
- The study explores the methylation of CpG sites in non-genital warts, a topic previously overlooked in low-risk HPV research.
- Researchers analyzed DNA from 24 pairs of wart and normal skin samples, using advanced methylation profiling techniques.
- Findings revealed significant hypo- and hypermethylation of numerous CpG sites associated with specific genes, indicating a distinct methylation pattern in these warts.