3,283 results match your criteria: "War-Related Injury & Illness Study Center[Affiliation]"

Article Synopsis
  • - The French Military Health Service established the Advanced Course for Deployment Surgery (ACDS) in 2008 to improve surgeons' skills in handling Non-Compressible Torso Hemorrhage (NCTH), a leading cause of preventable death in combat scenarios.
  • - A study comparing surgical practices before and after ACDS showed that post-course patients had more severe injuries and demonstrated improved techniques, such as increased use of temporary abdominal packing and reduced re-operations for bleeding.
  • - Overall, the ACDS effectively enhanced the readiness and performance of military surgeons, leading to better management of trauma cases, particularly through improved imaging and surgical techniques.
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Posttraumatic survivor guilt is associated with white matter microstructure alterations.

J Affect Disord

September 2024

Psychiatry Neuroimaging Laboratory, Department of Psychiatry, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; cBRAIN, Department of Child and Adolescent Psychiatry, Psychosomatics, and Psychotherapy, Ludwig-Maximilians-University, Munich, Germany; Department of Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; Department of Psychiatry, VA Boston Healthcare System, Brockton, MA, USA; Graduate School of Systemic Neurosciences, Ludwig-Maximilians-University, Munich, Germany. Electronic address:

Background: Military veterans with posttraumatic stress disorder (PTSD) commonly experience posttraumatic guilt. Guilt over commission or omission evolves when responsibility is assumed for an unfortunate outcome (e.g.

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A Double-Humanized Mouse Model for Studying Host Gut Microbiome-Immune Interactions in Gulf War Illness.

Int J Mol Sci

May 2024

Environmental Health and Disease Laboratory, Department of Environmental and Occupational Health, Program in Public Health, Susan and Henry Samueli College of Health Sciences, University of California, Irvine, CA 92697, USA.

Article Synopsis
  • Researchers have struggled for decades to find an effective treatment for Gulf War Illness (GWI), primarily due to the complex and variable symptoms and challenges of accurately modeling the illness in mice.
  • A new study developed a humanized-mouse model using a double engraftment strategy with a human immune system and microbiome, showing significant changes in gut microbiota and immune responses similar to those found in GWI veterans.
  • This innovative model may enhance our understanding of how gut health affects immune interactions in GWI, paving the way for potential future therapies.
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A Multipronged Approach to Caring for Women Veterans With Military Environmental Exposures.

Womens Health Issues

August 2024

Women's Operational Military Exposure Network Center of Excellence (WOMEN CoE), VA Palo Alto Health Care System, Palo Alto, California; California War Related Illness and Injury Study Center (CA WRIISC), VA Palo Alto Health Care System, Palo Alto, California.

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[Microbiological challenges in the treatment of war injuries].

Unfallchirurgie (Heidelb)

July 2024

Klinik für Unfallchirurgie und Orthopädie, Rekonstruktive und Septische Chirurgie, Sporttraumatologie, Bundeswehrkrankenhaus Ulm, Ulm, Deutschland.

The treatment of war injuries represents a continuing and recurrent challenge in modern reconstructive surgery. Previously, tumor resections and sepsis-related resections were mainly responsible for lengthy bone defects in Germany. In recent years another picture has increasingly emerged, particularly caused by the medical support of Ukraine.

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Article Synopsis
  • Many veterans experience intimate partner violence (IPV) and risk factors for this include things like combat experiences, PTSD, and depression.
  • The study looked at 49 male veterans to see if problems in their brain, specifically in the limbic system, relate to their likelihood of committing IPV.
  • Results showed that veterans with PTSD, depression, or other issues were more likely to engage in IPV, especially if they had more stress from war.
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Article Synopsis
  • Aggregate statistics help compare mortality rates in U.S. combat operations, but individual-level data on factors affecting casualty mortality has been hard to gather historically.* -
  • The DoD Trauma Registry provides valuable individual-level data from conflicts in Afghanistan and Iraq, allowing for detailed analyses of factors influencing combat casualty outcomes.* -
  • To better understand combat fatalities and improve survival rates, the commentary suggests integrating data from the Trauma Mortality Review with traditional aggregate statistics, focusing on prevention strategies for injuries.*
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[Initial in-hospital treatment of patients with penetrating trauma due to violence and war].

Unfallchirurgie (Heidelb)

July 2024

Klinik für Unfallchirurgie und Orthopädie, Rekonstruktive Chirurgie, Handchirurgie und Verbrennungsmedizin, Bundeswehrzentralkrankenhaus Koblenz, Koblenz, Deutschland.

Background: Current political and social developments have brought the topics of violence, in this context attributable to terrorism and sabotage, and since February 2022 awareness of war in particular has again greatly increased. This article aims to present the contextualized dealing with penetrating injuries in terms of initial in-hospital treatment.

Objective: The question remains to be answered as to what extent penetrating injuries require special attention and to what extent the treatment priorities, options and strategies as well as surgical treatment require adaptation of the usual approach in routine clinical practice in Germany.

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Background: Armed conflict injury is a growing public health concern, particularly in regions like the Middle East and North Africa (MENA). The protracted conflicts and political unrest in this region have led to a substantial number of injuries. Despite this, there is still limited understanding of the specific injury patterns stemming from conflicts, such as the 2006 Lebanon conflict.

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[National challenges for trauma surgery in Germany due to violence and war].

Unfallchirurgie (Heidelb)

July 2024

Klinik für Unfallchirurgie und Orthopädie, Rekonstruktive und Septische Chirurgie, Sporttraumatologie, Bundeswehrkrankenhaus Ulm, Ulm, Deutschland.

Due to the war in Ukraine and the treatment of patients with war wounds in the hospitals of the TraumaNetworks of the German Society for Trauma Surgery (TraumaNetzwerke DGU®), injuries from life-threatening mission situations (LebEL), terrorism, violence and war have become a matter of daily professional life. Furthermore, the societal and global feeling of security has fundamentally changed. The much-cited term "turning point in history", the reorientation of the Armed Forces and the investigation of the resilience of the healthcare system with respect to the "fitness for war", approximate to the description of the current challenges for trauma surgery (UCH) in Germany.

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[Challenge of limb care after violence and war with a special focus on imaging procedures].

Unfallchirurgie (Heidelb)

July 2024

Bundeswehrzentralkrankenhaus Koblenz, Klinik für Unfallchirurgie und Orthopädie, Rekonstruktive Chirurgie, Handchirurgie und Verbrennungsmedizin, Koblenz, Deutschland.

Background: Injury patterns in the area of the extremities following violence and war harbor many special features and require special attention. Destructive and complex defect injuries are often present, which necessitate elaborate and special reconstruction approaches, predominantly as part of a staged and multistaged procedure.

Research Question: In this context, special attention must be paid to the diagnostic options as an essential aspect, as a clear diagnosis means that targeted treatment steps can be planned and implemented.

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Cortical and Subcortical Brain Alterations in Specific Phobia and Its Animal and Blood-Injection-Injury Subtypes: A Mega-Analysis From the ENIGMA Anxiety Working Group.

Am J Psychiatry

August 2024

Department of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany (Hilbert, Boeken, Langhammer, Fehm, Lueken); Department of Psychology, Health and Medical University Erfurt, Erfurt, Germany (Hilbert); German Center for Mental Health, Partner Site Berlin/Potsdam, Berlin, Germany (Lueken); Neuroscience Institute, Department of Psychiatry and Mental Health, University of Cape Town, and South African Medical Research Council Unit on Child and Adolescent Health, Department of Paediatrics and Child Health, Red Cross War Memorial Children's Hospital, University of Cape Town, Cape Town, South Africa (Groenewold); Department of Psychiatry, Leiden University Medical Center, Leiden, the Netherlands (Bas-Hoogendam, Van der Wee); Department of Developmental and Educational Psychology, Institute of Psychology, Leiden University, Leiden, the Netherlands (Bas-Hoogendam); Leiden Institute for Brain and Cognition, Leiden, the Netherlands (Bas-Hoogendam, Van der Wee); Forensic Family and Youth Care Studies, Institute of Education and Child Studies, Leiden University, Leiden, the Netherlands (Aghajani); Department of Psychiatry, Amsterdam UMC location VUMC, Amsterdam (Aghajani, Veltman); Emotion and Development Branch, NIMH, Bethesda, Md. (Zugman, Harrewijn, Pine); Department of Psychology and Social Work, Mid Sweden University, Östersund, Sweden (Åhs); Institute for Translational Psychiatry (Arolt, Böhnlein, Dannlowski, Grotegerd, Leehr, Schrammen), Institute of Medical Psychology and Systems Neuroscience (Hofmann, T. Straube), and University Clinic for Radiology (Kugel), University of Münster, Münster, Germany; Institute for Clinical Psychology and Psychotherapy, Behavioral Epidemiology, Technische Universität Dresden, Dresden, Germany (Beesdo-Baum); Department of Psychology, Lund University, Lund, Sweden (Björkstrand); Munroe-Meyer Institute, University of Nebraska Medical Center, Omaha (Blackford); MRI Research Unit, Department of Radiology, Hospital del Mar, and IMIM-CIBER de Salud Mental, Instituto de Salud Carlos III, Barcelona, Spain (Blanco-Hinojo, Pujol); Institute of Diagnostic Radiology and Neuroradiology (Bülow), Department of Psychiatry and Psychotherapy (Grabe, Wittfeld), Functional Imaging Unit, Diagnostic Radiology and Neuroradiology (Lotze), and Institute for Community Medicine (Völzke), University Medicine Greifswald, Greifswald, Germany; Institut de Recerca Sant Pau (IR SANT PAU), Barcelona, Spain (Cano, Cardoner); Department of Psychiatry and Forensic Medicine, Universitat Autonòma de Barcelona, Barcelona, Spain (Cardoner); Centro de Investigación Biomédica en Red de Salud Mental, Carlos III Health Institute, Madrid (Cano, Cardoner); Department of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain (Cardoner); Department of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, U.K. (Caseras); Department of Psychiatry and Psychotherapy, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany (Domschke); Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, Tenn. (Feola); Department of Psychology, Uppsala University, Uppsala, Sweden (Fredrikson); Department of Psychiatry and Neuropsychology, Maastricht University Medical Center, Maastricht, the Netherlands (Goossens, Schruers); German Center for Neurodegenerative Diseases, Site Rostock/Greifswald, Greifswald, Germany (Grabe); Department of Psychiatry, University of Pennsylvania, Philadelphia (Gur, Satterthwaite); Department of Biological and Clinical Psychology, University of Greifswald, Greifswald, Germany (Hamm, Richter); Department of Psychology, Education, and Child Studies, Erasmus University Rotterdam, Rotterdam, the Netherlands (Harrewijn); Institute of Clinical Psychology and Psychotherapy, Technische Universität Dresden, Dresden, Germany (Heinig, Leonhardt, J. Schäfer); Department of Psychiatry, Psychosomatics, and Psychotherapy, Center of Mental Health, University Hospital Würzburg, Würzburg, Germany (Herrmann); Interdisciplinary Laboratory of Clinical Neuroscience and Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil (Jackowski, Pan); Department of Pediatrics, Masonic Institute for the Developing Brain, University of Minnesota, Minneapolis (Larsen); Core-Facility Brain Imaging, Faculty of Medicine (Jansen), and Department of Psychiatry (Krug, Nenadić, F. Stein), University of Marburg, Marburg, Germany; Department of Psychology, Vanderbilt University, Nashville, Tenn. (Kaczkurkin); Department of Psychology, University of Amsterdam, Amsterdam (Kindt, Visser); COMIC Research, Leeds and York Partnership NHS Foundation Trust, Leeds, U.K. (Kingsley); Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden (Klahn); LVR-University Hospital Essen, Department of Psychiatry and Psychotherapy, Faculty of Medicine, and Center for Translational Neuro- and Behavioral Sciences, University of Duisburg-Essen, Essen, North Rhine-Westphalia, Germany (Koelkebeck); Department of Psychiatry, University Hospital of Bonn, Bonn, Germany (Krug); Mental Health Research and Treatment Center, Faculty of Psychology, Ruhr-Universität Bochum, Bochum, Germany (Margraf); Laboratory of Affective Neuroscience in Poznan, SWPS University, Warsaw, Poland (Michałowski); Department of Psychology, Faculty of Human Sciences, and Institute for Cognitive and Affective Neuroscience, Medical School Hamburg, Hamburg, Germany (Muehlhan); Department of Psychology, University of Würzburg, Würzburg, Germany (Pauli, Schulz, Wiemer); Department of Clinical Psychology, Psychobiology, and Methodology, Universidad de La Laguna, San Cristóbal de La Laguna, Spain (Peñate, Rivero); Translational Psychotherapy, Institute of Psychology, University of Göttingen, Göttingen, Germany (Pittig); Department of Medicine, Health and Medical University, Potsdam, Germany (Plag); Department of Experimental Psychopathology, University of Hildesheim, Hildesheim, Germany (Richter); Department of Psychology, Faculty of Health Science, Universidad Europea de Canarias, La Orotava, Spain (Rivero); Section on Negative Affect and Social Processes, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil (Salum); Department of Psychology (A. Schäfer) and Department of Psychotherapy and Systems Neuroscience (Stark), Bender Institute of Neuroimaging, Justus Liebig University Giessen, and Center for Mind, Brain, and Behavior, Universities of Marburg and Giessen (A. Schäfer, Stark), Giessen, Germany; Department of Psychology, University of Graz, Graz, Austria (Schienle, Wabnegger); Clinical Child and Adolescent Psychology, Mental Health Research and Treatment Center, Faculty of Psychology, Ruhr-Universität Bochum, Bochum, Germany (Schneider); Department of Behavioral Medicine and Principles of Human Biology for the Health Sciences, Universität Trier, Trier, Germany (Schulz); Research Group Security and Privacy, Faculty of Computer Science, University of Vienna, Vienna (Seidl); Department of Psychiatry and Psychotherapy, University of Marburg, Marburg, Germany (Kircher, B. Straube, Yang); Department of Psychiatry and Neuroscience, Campus Charité Mitte, Charité-Universitätsmedizin Berlin, Berlin, Germany (Ströhle); Department of Psychology, Ruhr-Universität Bochum, Bochum, Germany (Suchan, Wannemüller); Imaging Genetics Center, Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, Marina del Rey (Thomopoulos, Jahanshad, Thompson); Department of Biological Psychology and Affective Science, Faculty of Human Sciences, University of Potsdam, Potsdam, Germany (Ventura-Bort, Wendt); Health Sciences, University of York, York, U.K. (Wright); Department of Psychiatry and Behavioral Sciences, University of Minnesota Medical School, Minneapolis (Zilverstand); KBO-Inn-Salzach-Klinikum, Wasserburg am Inn, Germany (Zwanzger); Department of Psychiatry and Psychotherapy, Ludwig Maximilians University of Munich, Munich, Germany (Zwanzger); Division of Human Genetics, School of Medicine, University of Texas Rio Grande Valley, Brownsville (Winkler); South African Medical Research Council Unit on Risk and Resilience in Mental Disorders, Neuroscience Institute, Department of Psychiatry and Mental Health, University of Cape Town, Cape Town, South Africa (D.J. Stein); Department of Education, Information, and Communications Technology and Learning, Østfold University College, Halden, Norway (Jackowski).

Article Synopsis
  • - The ENIGMA Anxiety Working Group studied brain structural differences between individuals with specific phobias and healthy participants, focusing on subtypes of phobias like animal and blood-injection-injury (BII) while examining how these differences relate to symptom severity and age.
  • - A total of 1,452 participants with phobias and 2,991 healthy subjects were analyzed, revealing that those with phobias exhibited smaller subcortical volumes and varying cortical thickness, especially noted in adults rather than youths.
  • - The results indicate that brain alterations in specific phobias are more significant than in other anxiety disorders, revealing distinct neural underpinnings linked to fear processing across different phobia types, highlighting a
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Article Synopsis
  • Blast and gunshot injuries are a significant cause of vascular trauma, especially in war-torn regions, presenting challenges due to delayed diagnosis and treatment in resource-limited settings.
  • A study reviewed 326 patients over five years, finding that the majority were young males, with gunshot wounds being the predominant cause, and most injuries involved the femoral artery.
  • The research highlighted the urgency of surgical intervention, noting a median revascularization time of 8.8 hours and a 5.8% mortality rate, with reversed saphenous vein grafts as the most common surgical treatment.
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Background: Hypertension and physical inactivity are risk factors for stroke. The effect of cardiorespiratory fitness (CRF) on stroke risk in patients with hypertension has not been assessed. We evaluated stroke incidence in patients with hypertension according to CRF and changes in CRF.

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Active-duty service members (ADSM) and military Veterans represent a population with increased occupational risk for nerve injuries sustained both during training operations and wartime. Mechanisms of war-related nerve injuries have evolved over time, from the musket ball-related traumas described by S.W.

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Family Physician's Satisfaction Report: Military 2021 vs. Civilian 2020 and 2022.

Mil Med

July 2024

War Related Illness & Injury Study Center (WRIISC), VA Medical Center, Washington, DC 20422, USA.

Introduction: In the Medscape 2020 Compensation Report, family physicians ranked low for feeling fairly compensated, choosing their specialty again and choosing medicine again. However, the Medscape data may not represent military family physicians.

Methods: A large survey was emailed to 2,562 military family physicians via a military professional organization list-serve from February to April 2021.

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Preliminary Evidence for the Role of Fungi, Specifically Chaetomium, in Gulf War Illness.

Mil Med

January 2025

Faculty of Medicine and Dentistry, Mackenzie Health Science Centre, University of Alberta, Edmonton, Alberta T6G 2B7, Canada.

Introduction: For veterans of the Persian Gulf War (1990-1991), dozens of possible causes for their illness have been proposed. We hypothesize that all may be correct. These may have weakened the immunity of the military personnel to fungal pathogens in the soil.

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Chinese hospital staff in anxiety and depression: Not only comfort patients but also should be comforted - A nationwide cross-sectional study.

J Affect Disord

September 2024

Division of Neuropsychiatry and Psychosomatics, Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China. Electronic address:

Article Synopsis
  • Healthcare professionals in China are experiencing high levels of anxiety (21%) and depression (21.4%), alongside significant allostatic overload (79.8%), due to a shortage of staff and increased work stress.
  • A study involving 9,433 hospital staff assessed various factors including stress, sleep quality (50.4% reported poor sleep), and episodic memory (32.1% had issues), revealing a concerning impact on their mental health and cognitive abilities.
  • The study highlights the need for local management and community support to help these workers cope with the intense demands of their roles and improve their overall well-being.
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Introduction: Post-traumatic seizures (PTSs) contribute to morbidity after traumatic brain injury (TBI). Early PTS are rare in combat casualties sustaining TBI, but the prevalence of late PTS is poorly described. We sought to define the prevalence and risk factors of late PTS in combat casualties with computed tomography evidence of TBI.

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This opinion article delves into the complexities of surgical care in conflict zones, highlighting the challenges and ethical considerations faced by humanitarian surgeons. It emphasizes the importance of collaboration with local healthcare professionals and specialized training programs in preparing surgeons for the unique demands of conflict trauma and war surgery.

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Exercise does not cause post-exertional malaise in Veterans with Gulf War Illness: A randomized, controlled, dose-response, crossover study.

Brain Behav Immun

August 2024

William S. Middleton Memorial Veterans Hospital, Madison, WI, USA; University of Wisconsin-Madison, Madison, WI, USA; James A. Haley Veterans' Hospital, Tampa, FL, USA. Electronic address:

Unlabelled: Chronic multisymptom illnesses (CMI) such as Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, Long-COVID, and Gulf War Illness (GWI) are associated with an elevated risk of post-exertional malaise (PEM), an acute exacerbation of symptoms and other related outcomes following exercise. These individuals may benefit from personalized exercise prescriptions which prioritize risk minimization, necessitating a better understanding of dose-response effects of exercise intensity on PEM.

Methods: Veterans with GWI (n = 40) completed a randomized controlled crossover experiment comparing 20 min of seated rest to light-, moderate-, and vigorous-intensity cycling conditions over four separate study visits.

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Introduction: Excess rates of Gulf War illness (GWI) and irritable bowel syndrome (IBS), two chronic multisymptom illnesses, have long been documented among nearly 700,000 veterans who served in the 1990-1991 Persian Gulf War. We sought to report the prevalence, characteristics, and association of GWI and IBS decades after the war in a clinical cohort of deployed Gulf War veterans (GWVs) who were evaluated at the Department of Veterans Affairs' War Related Illness and Injury Study Center (WRIISC) for unexplained chronic symptoms.

Materials And Methods: We analyzed data gathered from clinical intake questionnaires of deployed GWVs who were evaluated at WRIISC clinics between 2008 and 2020.

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Introduction: The Veterans Health Administration (VHA) established the Airborne Hazards and Open Burn Pit Registry (AHOBPR) in 2014 to address exposure concerns for veterans who have served in military operations in Southwest Asia and Afghanistan. By 2021, over 236,086 veterans completed the online questionnaire and 60% requested an AHOBPR examination. Of those requesting an exam, only 12% had an exam recorded in their medical record.

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