435 results match your criteria: "War Memorial Hospital[Affiliation]"

Article Synopsis
  • The study aimed to understand the prevalence and impact of neurological manifestations in hospitalized COVID-19 patients, comparing adults and children over a period spanning from January 2020 to May 2021.
  • Among 161,239 hospitalized patients, common neurological symptoms included fatigue, altered consciousness, and seizures, with adults showing a higher occurrence of strokes and other complications in ICU settings.
  • Key findings highlighted that stroke risk increased with age, while seizures and CNS infections were more prevalent in ICU among children; various health conditions also contributed to higher stroke risk in adults.
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WGO Guideline-Endoscope Disinfection Update.

J Clin Gastroenterol

January 2023

Consultant in Guideline Development, ALM Consulting, Amsterdam, The Netherlands.

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Healthcare relies upon the accurate and safe delivery of patient care. This is only achievable when systems are developed to ensure high quality, robust outcomes, for instance quality management systems. The concept of quality management can take on a different meaning depending on the context in which it is found.

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Unlabelled: The COVID-19 pandemic continues to test health systems resilience worldwide. Low- and middle-income country (LMIC) health care systems have considerable experience in disasters and disease outbreaks. Lessons from the preparedness and responses to COVID-19 in LMICs may be valuable to other countries.

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Background: Emergency care (EC) addresses the needs of patients with acute illness and injury, and has fulfilled a critical function during the COVID-19 pandemic. 'Processes' (e.g.

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Background: The COVID-19 pandemic highlighted challenges for all health systems worldwide. This research aimed to explore the impact of COVID-19 across the Pacific especially with regards to emergency care (EC) and clinicians' preparations and responses.

Methods: A collaboration of Australia and Pacific researchers conducted prospective qualitative research over 18 months of the pandemic.

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Unlabelled: Low- and middle-income countries (LMICs) across the Pacific region have been severely impacted by the COVID-19 pandemic, and emergency care (EC) clinicians have been on the frontline of response efforts. Their responsibilities have extended from triage and clinical management of patients with COVID-19 to health system leadership and coordination. This has exposed EC clinicians to a range of ethical and operational challenges.

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Background: Universal access to safe, effective emergency care (EC) during the COVID-19 pandemic has illustrated its centrality to healthcare systems. The 'Leadership and Governance' building block provides policy, accountability and stewardship to health systems, and is essential to determining effectiveness of pandemic response. This study aimed to explore the experience of leadership and governance during the COVID-19 pandemic from frontline clinicians and stakeholders across the Pacific region.

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Background: This study explores emergency care (EC) and other frontline healthcare worker (HCW) experiences responding to the COVID-19 pandemic in the Pacific region. The crisis has reinforced the crucial role well-trained, resourced, and supported EC providers play in supporting vital health systems and services in all global regions not only during 'business as usual' periods, but in times of tremendous stress and surge.

Methods: Qualitative data were collected from EC providers and relevant stakeholders in three research phases in 2020 and 2021.

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Objectives: While chest radiograph (CXR) is the first-line imaging investigation in patients with respiratory symptoms, differentiating COVID-19 from other respiratory infections on CXR remains challenging. We developed and validated an AI system for COVID-19 detection on presenting CXR.

Methods: A deep learning model (RadGenX), trained on 168,850 CXRs, was validated on a large international test set of presenting CXRs of symptomatic patients from 9 study sites (US, Italy, and Hong Kong SAR) and 2 public datasets from the US and Europe.

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Background: Typhoid fever is endemic in some Pacific Island Countries including Fiji and Samoa yet genomic surveillance is not routine in such settings. Previous studies suggested imports of the global H58 clade of var Typhi ( Typhi) contribute to disease in these countries which, given the MDR potential of H58, does not auger well for treatment. The objective of the study was to define the genomic epidemiology of Typhi in Fiji.

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Acute Respiratory Distress Syndrome (ARDS) accounts for 10% of ICU admissions and affects 3 million patients each year. Despite decades of research, it is still associated with one of the highest mortality rates in the critically ill. Advances in supportive care, innovations in technologies and insights from recent clinical trials have contributed to improved outcomes and a renewed interest in the scope and use of Extracorporeal life support (ECLS) as a treatment for severe ARDS, including high flow veno-venous Extracorporeal Membrane Oxygenation (VV-ECMO) and low flow Extracorporeal Carbon Dioxide Removal (ECCO2R).

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Importance: In children undergoing heart surgery, nitric oxide administered into the gas flow of the cardiopulmonary bypass oxygenator may reduce postoperative low cardiac output syndrome, leading to improved recovery and shorter duration of respiratory support. It remains uncertain whether nitric oxide administered into the cardiopulmonary bypass oxygenator improves ventilator-free days (days alive and free from mechanical ventilation).

Objective: To determine the effect of nitric oxide applied into the cardiopulmonary bypass oxygenator vs standard care on ventilator-free days in children undergoing surgery for congenital heart disease.

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Objectives: There are scant primary clinical data on antimicrobial resistance (AMR) burden from low- and middle-income countries (LMICs). We adapted recent World Health Organization methodology to measure the effect of third-generation cephalosporin resistance (3GC-R) on mortality and excess length of hospital stay in Fiji.

Methods: We conducted a prospective cohort study of inpatients with Enterobacterales bloodstream infections (BSIs) at Colonial War Memorial Hospital, Suva.

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Nosocomial Pneumonia in the Mechanically Ventilated Patient.

Semin Respir Crit Care Med

June 2022

Critical Care Research Group, The Prince Charles Hospital, Brisbane, Australia.

Article Synopsis
  • - Ventilator-associated pneumonia (VAP) is a significant complication for critically ill patients on mechanical ventilation, leading to high rates of infection and mortality, especially from multidrug-resistant pathogens.
  • - Effective prevention and treatment strategies include following international guidelines, using a combination of pharmacological and non-pharmacological interventions, and promptly collecting respiratory samples for diagnostic purposes.
  • - It's crucial to adjust antimicrobial treatment based on patient response after 3 to 5 days and to explore new antibiotics due to increasing drug resistance affecting VAP outcomes.
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Introduction: Noninvasive neuromonitoring could be a valuable option for bedside assessment of cerebral dysfunction in patients with coronavirus disease-2019 (COVID-19) admitted to intensive care units (ICUs). This systematic review aims to investigate the use of noninvasive multimodal neuromonitoring in critically ill adult patients with COVID-19 infection.

Methods: MEDLINE/PubMed, Scopus, Cochrane, and EMBASE databases were searched for studies investigating noninvasive neuromonitoring in patients with COVID-19 admitted to ICUs.

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Background: The first aim of this study was to investigate the impact of providing an additional four hours of Saturday occupational therapy to patients receiving Saturday physiotherapy in an inpatient setting on length of stay, functional independence, gait and balance. The second aim was to conduct an economic evaluation to determine if the introduction of a Saturday occupational therapy service in addition to physiotherapy resulted in a net cost savings for the rehabilitation facility.

Methods: A prospective cohort study with a historical control was conducted in an Australian private mixed rehabilitation unit from 2015-2017.

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Introduction: Trauma causes 40% of child deaths in high-income countries, with haemorrhage being a leading contributor to death in this population. There is a growing recognition that fibrinogen and platelets play a major role in trauma-induced coagulopathy (TIC) but the exact physiological mechanisms are poorly understood.

Methods And Analysis: This is a prospective multicentre, open-label, randomised, two-arm parallel feasibility study conducted in the emergency departments, intensive care units and operating theatres of participating hospitals.

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Article Synopsis
  • The study aimed to compare the outcomes of patients with COVID-19 respiratory failure treated with extracorporeal membrane oxygenation (ECMO) vs. conventional mechanical ventilation.
  • Using data from over 7,300 patients across 30 countries, results indicated that ECMO reduced hospital mortality to 26.0% compared to 33.2% for those on conventional treatment, showing a significant risk difference in favor of ECMO.
  • Findings highlighted that ECMO was particularly effective in younger patients (under 65) and those with severe hypoxia, suggesting the importance of patient age and condition in determining treatment effectiveness.
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Introduction: Neurological complications are frequent in patients with coronavirus disease-2019 (COVID-19). The use of non-invasive neuromonitoring in subjects without primary brain injury but with potential neurological derangement is gaining attention outside the intensive care unit (ICU). This systematic review and meta-analysis investigates the use of non-invasive multimodal neuromonitoring of the brain in non-critically ill patients with COVID-19 outside the ICU and quantifies the prevalence of abnormal neuromonitoring findings in this population.

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Background: Achieving good outcomes in type 2 diabetes mellitus patients' needs a decent integrated care service with access to resources. The Fiji Islands has one of the highest rates of diabetes disease burden and has available resources to alleviate the diabetic disease pandemic in its population, yet patient outcomes are getting worse. We hypothesize that a dysfunction in health-care delivery system may be accentuating the diabetic disease process; therefore, this service evaluation study was conducted to provide insight into the management of T2DM in a secondary care clinic setting.

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Add-on Therapies in VA-ECMO for Cardiogenic Shock: The Heart Recovers, Yet Other Organs Suffer.

J Cardiothorac Vasc Anesth

July 2022

Critical Care Research Group, University of Queensland and The Prince Charles Hospital, Brisbane, Queensland, Australia; Intensive Care Department, St. Andrews War Memorial Hospital, Brisbane, Queensland, Australia.

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Background: bacteraemia (SAB) is one of the commonest bloodstream infections globally and is associated with a high mortality rate. Most published data comes from temperate, high-income countries. We describe the clinical epidemiology, microbiology, management and outcomes of patients with SAB treated in a tropical, middle-income setting at Fiji's largest hospital.

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