2 results match your criteria: "Wake Forest University 1834 Wake Forest Road[Affiliation]"
Chem Sci
November 2021
Department of Chemistry and Chemical Biology, Rutgers University 123 Bevier Road Piscataway NJ 08854 USA
Nano Life
January 2013
Department of Physics, Wake Forest University 1834 Wake Forest Road, Winston-Salem, NC 27106, USA.
The interaction between platelet integrin IIb3 and fibrin(ogen) plays a key role in blood clot formation and stability. Integrin antagonists, a class of pharmaceuticals used to prevent and treat cardiovascular disease, are designed to competitively interfere with this process. However, the energetics of the integrin-drug binding are not fully understood, potentially hampering further development of this class of pharmaceuticals.
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