483 results match your criteria: "WI 53792-3252; and Cleveland Clinic Lerner College of Medicine[Affiliation]"

Noninvasive Quantitative CT for Diffuse Liver Diseases: Steatosis, Iron Overload, and Fibrosis.

Radiographics

January 2025

From the Department of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, E3/311 Clinical Science Center, Madison, WI 53792-3252; and the American College of Radiology (ACR) Institute for Radiologic Pathology, Silver Spring, Md.

Chronic diffuse liver disease continues to increase in prevalence and represents a global health concern. Noninvasive detection and quantification of hepatic steatosis, iron overload, and fibrosis are critical, especially given the many relative disadvantages and potential risks of invasive liver biopsy. Although MRI techniques have emerged as the preferred reference standard for quantification of liver fat, iron, and fibrosis, CT can play an important role in opportunistic detection of unsuspected disease and is performed at much higher volumes.

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Access to Breast Cancer Screening: Disparities and Determinants- Expert Panel Narrative Review.

AJR Am J Roentgenol

November 2024

Professor, Division Chief Breast Imaging, UC San Diego Health, 9400 Campus Point Dr., La Jolla, CA 92037.

While breast cancer screening reduces mortality, disparities in access continue to limit equitable care. Medically underserved groups-including American Indian or Alaska Native, Black, Hispanic, disabled, and LGBTQ+ individuals-face significant barriers in accessing screening mammography services. This AJR Expert Panel Narrative Review leverages the National Institute on Minority Health and Health Disparities Research Framework to analyze persistent inequities in screening, focusing on race, ethnicity, socioeconomic status, disabilities, health insurance, and geography.

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Update on MR Imaging of the Acetabular Labrum.

Magn Reson Imaging Clin N Am

February 2025

Department of Radiology, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue - CSC, Madison, WI 53792-3252, USA.

Acetabular labral tears are a mechanical cause of hip pain. Hip MR imaging should be performed on 3T magnets using small field of view and high-resolution imaging. If using a lower strength magnet, direct arthrography should be performed.

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Spectrum of Heterotopic and Ectopic Splenic Conditions.

Radiographics

November 2024

From the Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3/311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792-3252 (L.W.N., M.G.L., P.J.P.); Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Mo (S.M.B., S.B.); and American College of Radiology (ACR) Institute for Radiologic Pathology (AIRP), Silver Spring, Md (M.G.L., P.J.P.).

A spectrum of heterotopic and ectopic splenic conditions may be encountered in clinical practice as incidental asymptomatic detection or symptomatic diagnosis. The radiologist needs to be aware of these conditions and their imaging characteristics to provide a prompt correct diagnosis and avoid misdiagnosis as neoplasm or lymphadenopathy. Having a strong knowledge base of the embryologic development of the spleen improves understanding of the pathophysiologic basis of these conditions.

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Diabetes mellitus and metabolic syndrome are closely linked with visceral body composition, but clinical assessment is limited to external measurements and laboratory values including hemoglobin A1c (HbA1c). Modern deep learning and AI algorithms allow automated extraction of biomarkers for organ size, density, and body composition from routine computed tomography (CT) exams. Comparing visceral CT biomarkers across groups with differing glycemic control revealed significant, progressive CT biomarker changes with increasing HbA1c.

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Sinonasal Tumors: What the Multidisciplinary Cancer Care Board Wants to Know.

Radiographics

October 2024

From the Department of Radiology, Division of Neuroradiology (G.D.A., T.A.K.), Department of Otorhinolaryngology (I.J.K.), Department of Pathology, Division of Human Oncology (L.A.E.), Department of Human Oncology (A.R.B.), and Department of Medicine, Division of Human Oncology (J.Y.B.), University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, Madison, WI 53792-3252; Department of Radiology, Medical College of Wisconsin, Milwaukee, Wis (M.A.); California Advanced Imaging Medical Associates, San Francisco, Calif (M.A.M.); and University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin (L.P.).

Article Synopsis
  • Sinonasal neoplasms encompass a wide variety of tumor types, ranging from benign lesions to aggressive cancers, reflecting the diverse tissue types in the nasal cavities and sinuses.
  • Recent advancements in understanding the genetic and molecular factors influencing sinonasal tumor behavior have led to the identification of new tumor types and an updated classification in the World Health Organization's fifth edition for head and neck tumors.
  • It's essential for radiologists to be familiar with this new classification to accurately assess tumor behavior and effectively participate in patient care decisions alongside a multidisciplinary cancer team.
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Intrapatient Changes in CT-Based Body Composition After Initiation of Semaglutide (Glucagon-Like Peptide-1 Receptor Agonist) Therapy.

AJR Am J Roentgenol

December 2024

Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3/311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792-3252.

The long-acting glucagon-like peptide-1 receptor agonist semaglutide is used to treat type 2 diabetes or obesity in adults. Clinical trials have observed associations of semaglutide with weight loss, improved control of diabetes, and cardiovascular risk reduction. The purpose of this study was to evaluate intrapatient changes in body composition after initiation of semaglutide therapy by applying an automated suite of CT-based artificial intelligence (AI) body composition tools.

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Fostering Organizational Excellence through Inclusive Leadership: Practical Guide for Radiology Leaders.

Radiographics

September 2024

From the Department of Radiology, University of Wisconsin-Madison School of Medicine and Public Health, 600 Highland Ave, F6/178C, Madison, WI 53792-3252 (A.K.N., N.B., R.W.W.); Memorial Sloan Kettering Cancer Center, New York, NY (N. Monga, V.L.M.); Medical College of Wisconsin, Milwaukee, Wis (N. McFarlane); University of Wisconsin-Madison School of Business, Madison, Wis (M.S., A.S.); and Clement J. Zablocki Veterans Affairs Medical Center, Milwaukee, Wis (I.A.W.).

Inclusive leadership styles value team members, invite diverse perspectives, and recognize and support the contributions of employees. The authors provide guidance to radiology leaders interested in developing inclusive leadership skills and competencies to improve workforce recruitment and retention and unlock the potential of a rapidly diversifying health care workforce. As health care organizations look to attract the best and brightest talent, they will be increasingly recruiting millennial and Generation Z employees, who belong to the most diverse generations in American history.

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Harnessing the Value of Incidental Tissue and Organ Data at Body CT.

Radiology

August 2024

From the Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3/311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792-3252.

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Article Synopsis
  • - The study aimed to identify CT scan characteristics of abdominopelvic Castleman disease, particularly focusing on a new finding related to the surrounding fat tissue (perinodal fat).
  • - Researchers analyzed data from 76 adults with confirmed Castleman disease and evaluated factors like nodal mass size, enhancement patterns, and fat infiltration.
  • - Results showed that a majority of cases had hypervascular nodal masses and fat infiltration, indicating that these features might help accurately diagnose Castleman disease, especially the hyaline vascular variant (HVV).
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Objective: Fully-automated CT-based algorithms for quantifying numerous biomarkers have been validated for unenhanced abdominal scans. There is great interest in optimizing the documentation and reporting of biophysical measures present on all CT scans for the purposes of opportunistic screening and risk profiling. The purpose of this study was to determine and adjust the effect of intravenous (IV) contrast on these automated body composition measures at routine portal venous phase post-contrast imaging.

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O-RADS MRI risk stratification system: pearls and pitfalls.

Insights Imaging

February 2024

Sorbonne Université, INSERM UMR S 938 (CRSA - 75012), Assistance Publique des Hôpitaux de Paris, Hopital Tenon, Service IRIS, Paris, France.

In 2021, the American College of Radiology (ACR) Ovarian-Adnexal Reporting and Data System (O-RADS) MRI Committee developed a risk stratification system and lexicon for assessing adnexal lesions using MRI. Like the BI-RADS classification, O-RADS MRI provides a standardized language for communication between radiologists and clinicians. It is essential for radiologists to be familiar with the O-RADS algorithmic approach to avoid misclassifications.

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Percutaneous Microwave Ablation for Treatment of Retroperitoneal Tumors.

Radiol Imaging Cancer

March 2024

From the Departments of Radiology (A.E.R., A.M.Z., A.B.C., T.J.Z., J.L.H., E.J.A., M.G.L., E.M.K.K., S.A.W., L.M.S., P.F.L., F.T.L.), Biomedical Engineering (A.E.R., F.T.L.), Biostatistics and Medical Informatics (L.M.), and Urology (J.L.H., E.J.A., F.T.L.), University of Wisconsin-Madison School of Medicine and Public Health, 600 Highland Ave, E3/378 Clinical Science Center, Madison, WI 53792-3252; and Cleveland Clinic Lerner College of Medicine, Cleveland, Ohio (E.A.K.).

Purpose To determine if microwave ablation (MWA) of retroperitoneal tumors can safely provide high rates of local tumor control. Materials and Methods This retrospective study included 19 patients (median age, 65 years [range = 46-78 years]; 13 [68.4%] men and six [31.

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Invited Commentary: Metabolic Syndrome: The Urgent Need for an Imaging-based Definition.

Radiographics

March 2024

From the Department of Radiology, The University of Wisconsin School of Medicine and Public Health, E3/311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792-3252.

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Natural History of Colorectal Polyps Undergoing Longitudinal in Vivo CT Colonography Surveillance.

Radiology

January 2024

From the Departments of Radiology (B.D.P., D.H.K., P.J.P.), Pathology and Laboratory Medicine (K.A.M.), Biostatistics and Informatics (M.A.N.), Medicine (R.B.H.), and Oncology (R.B.H.), University of Wisconsin School of Medicine and Public Health, E3/311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792-3252; William S. Middleton Memorial Veterans Hospital and Clinics, Madison, Wis (K.A.M.); Department of Statistics, College of Letters and Science, University of Wisconsin, Madison, Wis (M.A.N.); Division of Gastroenterology, Department of Medicine, University of Washington School of Medicine, Seattle, Wash (W.M.G.); Division of Translational Science and Therapeutics, Fred Hutchinson Cancer Center, Seattle, Wash (W.M.G.); Department of Biomedical Sciences, Humanitas University, Milan, Italy (C.H.); and Endoscopy Unit, IRCCS Humanitas Research Hospital, Milan, Italy (C.H.).

Background The natural history of colorectal polyps is not well characterized due to clinical standards of care and other practical constraints limiting in vivo longitudinal surveillance. Established CT colonography (CTC) clinical screening protocols allow surveillance of small (6-9 mm) polyps. Purpose To assess the natural history of colorectal polyps followed with CTC in a clinical screening program, with histopathologic correlation for resected polyps.

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Functional Anatomy of the Spinal Cord.

Radiol Clin North Am

March 2024

Department of Radiology, University of Wisconsin School of Medicine and Public Health, E1/318, 600 Highland Avenue, Madison, WI 53792-3252, USA. Electronic address:

Localization of lesions in the spinal cord requires knowledge of the functional anatomy of gray and white matter tracts. Using decussation points for white matter tracts can help determine lesion level. Pathologies can affect gray and white matter tracts in distinct ways and pattern recognition can help narrow down the differential diagnosis.

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O-RADS scoring system for adnexal lesions: Diagnostic performance on TVUS performed by an expert sonographer and MRI.

Eur J Radiol

December 2023

Département d'Imageries Radiologiques et Interventionnelles Spécialisées (IRIS), Hôpital Tenon, Assistance Publique-Hôpitaux de Paris, France; Sorbonne Université, INSERM U938 Équipe Biologie et Thérapeutiques du Cancer, France. Electronic address:

Rationale And Objective: To determine the diagnostic performance of transvaginal ultrasound (TVUS) performed by an US specialist and MRI based on the O-RADS scoring system.

Materials And Methods: Between March 5th 2013 and December 31st 2021, 227 patients, referred to our center, underwent TVUS and pelvic MRI for characterization of an adnexal lesion proven by surgery or two years of negative follow-up. All lesions were classified according to O-RADS US and O-RADS MRI risk scoring systems.

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Update: Lung-RADS 2022.

Radiographics

November 2023

From the Department of Radiology, University of Wisconsin School of Medicine, 600 Highland Ave, Madison, WI 53792-3252 (M.D.M., J.P.K., L.S.B., C.A.M.); and Department of Radiology, University of Michigan Health System, Ann Arbor, Mich (E.A.K.).

- Update articles supplement or update information found in full-length articles previously published in . These updates, written by at least one author of the previous article, provide a brief synopsis that emphasizes important new information such as technological advances, revised imaging protocols, new clinical guidelines involving imaging, or updated classification schemes.

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Breast-specific positron imaging systems provide higher sensitivity than whole-body PET for breast cancer detection. The clinical applications for breast-specific positron imaging are similar to breast MRI including preoperative local staging and neoadjuvant therapy response assessment. Breast-specific positron imaging may be an alternative for patients who cannot undergo breast MRI.

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Breast Imaging and Intervention during Pregnancy and Lactation.

Radiographics

October 2023

From the Department of Radiology (M.S.P., A.R.G., M.A.E., L.R.S., R.W.W., A.K.N., R.M.S., A.M.F.), Department of Medical Physics (L.R.S., R.M.S., A.M.F.), and Department of Pathology and Laboratory Medicine (M.R.), University of Wisconsin School of Medicine and Public Health, 600 Highland Ave, Madison, WI 53792-3252; and University of Wisconsin Carbone Cancer Center, Madison, Wis (A.K.N., R.M.S., A.M.F.).

Article Synopsis
  • Pregnancy and breastfeeding change how breasts look and feel, which makes it trickier to check for breast cancer.
  • It's still really important to do these checks to catch any cancer early, as waiting could make things worse.
  • Doctors use different types of scans, like ultrasound or mammography, depending on the woman’s age and situation, but MRI is not usually used during pregnancy.
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Comparison of MiraLAX and magnesium citrate for bowel preparation at CT colonography.

Abdom Radiol (NY)

November 2023

Department of Radiology, University of Wisconsin School of Medicine & Public Health, E3/311 Clinical Science Center, 600 Highland Ave., Madison, WI, 53792-3252, USA.

Purpose: To compare MiraLAX, a hypo-osmotic lavage, and magnesium citrate (MgC), a hyper-osmotic agent for bowel preparation at CTC.

Methods: 398 total screening CTC studies were included in this retrospective, single institution study. 297 underwent preparation with a double-dose MgC regimen (mean age, 61 ± 5.

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MRI-based vertebral bone quality score: relationship with age and reproducibility.

Osteoporos Int

December 2023

Department of Orthopedics and Rehabilitation, School of Medicine and Public Health, University of Wisconsin, 600 Highland Ave, Madison, WI, 53792-3252, USA.

Unlabelled: Vertebral bone quality (VBQ) score is an opportunistic measure of bone mineral density using routine preoperative MRI in spine surgery. VBQ score positively correlates with age and is reproducible across serial scans. However, extrinsic factors, including MRI machine and protocol, affect the VBQ score and must be standardized.

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Article Synopsis
  • Precontrast CT is typically used to assess hepatic steatosis, but this study investigates the effectiveness of portal venous phase postcontrast CT via AI measurements for detecting moderate steatosis.
  • The research analyzed data from 2,777 patients, determining that 13.9% had at least moderate steatosis, revealing significant differences in liver and spleen attenuation measurements between those with and without the condition.
  • Results indicated that postcontrast liver attenuation had superior diagnostic performance for detecting moderate steatosis (AUC = 0.938) compared to the postcontrast liver-spleen attenuation difference (AUC = 0.832).
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Automated Deep Learning Artificial Intelligence Tool for Spleen Segmentation on CT: Defining Volume-Based Thresholds for Splenomegaly.

AJR Am J Roentgenol

November 2023

Department of Radiology, The University of Wisconsin School of Medicine & Public Health, E3/311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792-3252.

Splenomegaly historically has been assessed on imaging by use of potentially inaccurate linear measurements. Prior work tested a deep learning artificial intelligence (AI) tool that automatically segments the spleen to determine splenic volume. The purpose of this study is to apply the deep learning AI tool in a large screening population to establish volume-based splenomegaly thresholds.

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