3 results match your criteria: "WHO Collaborating Centre for Enteroviruses and Viral Vaccines[Affiliation]"
Estimating prevalence of Enterovirus D111 in human and non-human primate populations using cross-sectional serology.
J Gen Virol
November 2023
Microbiology Services, NHS Blood Transfusion, London, UK.
Article Synopsis
- Enteroviruses mainly impact young children, with recent outbreaks highlighting the potential severity of strains like EV-D68 and EV-A71, as well as new cases of atypical hand-foot-and-mouth disease caused by CVA6.
- EV-D111, an enteric pathogen found in Central Africa, has been under-researched, although recent studies indicate its antibodies are prevalent in both humans (55-83%) and wildlife, suggesting prior infections are common and that the virus circulates undetected.
- The seroprevalence of EV-D111 varies by age in the UK, being highest in younger (1-5 years) and older adults (>60 years), and further surveillance is needed to improve understanding of its epidemiology and
Enteroviruses-the famous unknowns.
Lancet Infect Dis
March 2020
WHO Collaborating Centre for Enteroviruses and Viral Vaccines, Paris, France.
Genetic and phenotypic characterization of recently discovered enterovirus D type 111.
PLoS Negl Trop Dis
October 2019
Institut Pasteur-Unité de biologie des virus entériques-Paris, France.
Article Synopsis
- - The Enterovirus D (EV-D) species, particularly EV-D68 and EV-D70, have caused outbreaks in humans for decades but have received little research attention until recent severe respiratory diseases linked to EV-D68.
- - Newly identified EV-D types (EV-D94, EV-D111, and EV-D120) were discovered in Africa but have not been reported elsewhere, with some strains suggesting a possible zoonotic origin from non-human primates.
- - Genetic analysis of EV-D111 strains indicates recent zoonotic transmission and potential genetic recombination with EV-D94, raising concerns about misclassification during poliovirus detection in Central Africa, where both viruses coexist.