30,719 results match your criteria: "W.W.; and Dana-Farber Cancer Institute[Affiliation]"

Article Synopsis
  • - The study evaluates the safety of using thermochemically treated sewage sludge from a distillery's wastewater treatment plant as a soil additive by examining its physicochemical properties and the bioaccumulation of heavy metals in maize.
  • - Pyrolysis at 400 °C alters the sludge's characteristics positively, increasing pH, carbon, nitrogen, and ash content, while reducing electrical conductivity, cation exchange capacity, and harmful polycyclic aromatic hydrocarbons.
  • - Results show that adding 1% biochar from the treated sludge improves soil properties and doesn't enhance heavy metal uptake in maize or affect cress seed germination, though it does impact the soil's microbial community.
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The Effect of Recycled Geogrid Fibres on Asphalt Concrete Performance: A Case Study from Poland.

Materials (Basel)

December 2024

Department of Civil Engineering and Architecture, Kielce University of Technology, Al. Tysiąclecia Państwa Polskiego 7, 25-314 Kielce, Poland.

This study articulates findings from research pertaining to the utilisation of recycled geogrid in asphalt concrete. The issue of contamination of reclaimed waste with geosynthetic materials persists as a significant concern that warrants attention. In Poland, the allowable quantity of geogrid contaminants within the mineral-asphalt composition is 0.

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Leather waste contains up to 10% nitrogen (N); thus, combustion or gasification only for the energy recovery would not be rational, if safety standards are met. On the other hand, the chromium (Cr) content exceeding 5% in half of the waste stream (/) is too significant to be applied in agriculture. In this work, four acid hydrolysates from leather waste shavings, both wet-white free of Cr and wet-blue with Cr, were used: two with a mixture of acids and supplemented with Cu, Mn, and Zn, and the other two as semi-products from collagen extraction using hydrochloric acid.

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This study evaluates how the polarity of the medium affects the binding efficiency of hydrophobic ligands with human serum albumin (HSA). The polarity of the aqueous medium was changed by adding 1,4-dioxane in concentrations of 0%, 10%, and 20% /, resulting in solvent mixtures with decreasing dielectric constants (ε = 80, 72, and 63). The addition of 1,4-dioxane did not affect the integrity of the protein, as confirmed by Far-UV-CD, Rayleigh scattering, and time-resolved fluorescence experiments.

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Biodegradable polymers and bioceramics give rise to composite structures that serve as scaffolds to promote tissue regeneration. The current research explores the preparation of biodegradable filaments for additive manufacturing. Bioresorbable segmented poly(ester urethanes) (SPEUs) are easily printable elastomers but lack bioactivity and present low elastic modulus, making them unsuitable for applications such as bone tissue engineering.

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Article Synopsis
  • Itraconazole (ITZ) is a broad-spectrum antifungal with low oral bioavailability due to poor solubility and potential dose-related side effects.
  • Researchers aimed to improve ITZ's solubility using various water-soluble polymers and developed personalized, programmable release tablets.
  • The study found that using hot melt extrusion (HME) combined with 3D printing can enhance ITZ solubility and allow for precise control of its release, offering a promising method for personalized drug delivery.
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Although a lot of recent research revealed advantages of novel biopolymers' implementation as active food packaging polymers, there is not an equivalent effort from industry to use such films, probably because of the required cost to change the supply chain and the equipment. This study investigates the use of two natural abundant nanoclays, laponite (Lap) and montmorillonite (Mt), as eugenol slow-release carriers for enhancing the functionality of low-density polyethylene (LDPE) active packaging films. The target is to combine the spirit of the circular economy with the existent technology and the broadly used materials to develop a novel attractive product for active food packaging applications.

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The purpose of this research is to study the effect of the steam explosion (SE) process on curcumin extraction from fresh turmeric chips. Fresh turmeric chips abruptly disintegrated during the steam explosion process. The investigation into the turmeric particles following the steam explosion process in the SEM micrographs revealed that the formation of surface cracks and cavities led to an increase in the surface area of turmeric particles.

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In the current study, we aimed to evaluate the combined antimelanogenic effects of resveratrol- and protopanaxadiol (PPD)-enriched rice seed extracts (DJ526 and DJ-PPD) in melan-a cells. The treatment antioxidant capacity was evaluated using the ABTS radical scavenging method. TR_3 (70% [wight ()/] of DJ526 and 30% [/] of DJ-PPD) markedly increased the antioxidant activity at a level similar to that of DJ526 and DJ-PPD alone.

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Cadmium (Cd) contamination threatens human health and plant growth due to its accumulation in edible parts. The sole application of phosphorus-solubilizing bacteria (PSB), biochar (BC), and phosphorus (P) effectively mitigates Cd's adverse effects in contaminated agricultural systems. However, further investigation into their combined impacts on Cd toxicity and maize () production is essential.

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Fabrication and Encapsulation of Soy Peptide Nanoparticles Using Ultrasound Followed by Spray Drying.

Foods

December 2024

National Engineering Laboratory of Wheat & Corn Further Processing, School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.

Peptide aggregation inevitably occurs during hydrolysis, and insoluble peptide aggregates (ISPA) are used as feed for animals due to their poor water solubility and unpleasant bitter flavor. Ultrasound was used to fabricate soy peptide nanoparticles by reassembling ISPA, followed by spray-drying encapsulation to develop low-bitterness peptide microcapsules with soluble soybean polysaccharide (SSPS) and stevioside (STE) as wall materials. Powder properties, bitter taste, and the morphology of the microcapsules were evaluated.

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Resistant Starch Type 5 Formation by High Amylopectin Starch-Lipid Interaction.

Foods

December 2024

Posgrado en Ciencia y Tecnología de los Alimentos, Facultad de Química, Universidad Autónoma de Querétaro, Centro Universitario, Santiago de Querétaro 76010, Mexico.

The formation of resistant starch type 5 (RS5), primarily associated with amylose-lipid complexes, is typically attributed to starches with high-amylose content due to their affinity for lipid interactions. Recently, studies have also investigated the potential of amylopectin-rich starches to form amylopectin-lipid complexes (ALCs), expanding RS5 sources. This study explores the capacity of waxy corn starch (WS), which is rich in amylopectin, to develop ALCs with oleic acid (10% /) under different thermal and mechanical conditions.

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The optimum processing conditions for green laver chips were determined using response surface methodology (RSM) to improve taste and reduce off-flavors by applying reaction flavor and air-frying techniques. The optimum composition (/) for the chips included 20% green laver, 20% hairtail surimi, and 60% flour. Additional ingredients included distilled water (90 mL) with GDL (3 g), NaHCO₃ (2 g), salt (1 g), sugar (12 g), roasted soybean powder (1.

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Impact of Reconstitution Conditions on the Solubility of Faba Bean Protein Isolate.

Foods

November 2024

Advanced Food Systems Research Unit, Institute for Sustainable Industries and Liveable Cities, College of Sports, Health and Engineering, Victoria University, Melbourne 8001, Australia.

Faba bean protein isolate (FBPI) is emerging as a promising protein ingredient in the food industry. However, a lack of comprehensive scientific understanding of its functional properties, particularly solubility, limits broader application. This study investigated the reconstitution behaviour of FBPI under different conditions.

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To enhance the functionality of honey, particularly its antioxidant capacity, the incorporation of polyphenols (AMPs) is an effective approach. The preparation technology and antioxidant activity of AMP added to honey were studied. AMP was extracted with ethanol and its components were analyzed and then mixed evenly with honey in different addition amounts (0.

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The influence of heating as a pretreatment on the structural and functional attributes of milk protein concentrate (MPC) powders derived from ultrafiltered/diafiltered (UF/DF) skim milk is under-reported. This research delves into the impact of pH and heat treatment on skim milk's properties before UF/DF and how these changes affect the resulting MPC powders. By adjusting the pH of skim milk to 6.

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This work aimed to propose the reuse of processing waste from the Sicilian almond ( Batsch.) cultivar Tuono for the formulation of a new functional baked product (muffin) that is gluten- and lactose-free. Muffins were prepared using orange juice, rice flour, extra virgin olive oil, and enriched almond skin (3% and 6% /).

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Metabolomic Profiling of Reared on Chestnut Shell-Enriched Substrate Using NMR Spectroscopy.

Foods

November 2024

Department of Veterinary Medicine and Animal Sciences-DIVAS, University of Milan, Via dell'Università 6, 26900 Lodi, Italy.

The aim of this study was to evaluate the metabolomic profile of larvae reared on the following innovative growth substrates: wheat bran (control, CTRL); wheat bran supplemented with 12.5% / chestnut shell (TRT1); and wheat bran supplemented with 25% / chestnut shell (TRT2) for 14 days of trial. At the end of this experiment, larvae were transformed into insect meals for nutritional characterization.

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A Novel Normalized Quantitative Real-Time PCR Approach for Ensuring Roe Deer () Meat Authenticity in Game Meat Foods.

Foods

November 2024

LAQV/REQUIMTE, Faculdade de Farmácia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal.

Roe deer meat is a prized game product in many European countries. However, concerns exist regarding the accuracy of the amount of declared roe deer in processed game meat foods. This study aimed to develop a reliable method for the detection and quantification of roe deer in commercialized game meat products.

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The SRealCLL study described the occurrence of adverse events (AEs) and healthcare resource utilization in patients with chronic lymphocytic leukaemia (CLL) using artificial intelligence in a real-world scenario in Spain. We collected real-world data on patients with CLL from seven Spanish hospitals between January 2016 and December 2018, focusing on their AE and healthcare service utilization. Data extraction from electronic health records of 385,904 patients was performed using the EHRead technology, which is based on natural language processing and machine learning.

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High-dose modified-release formulation of a poorly soluble drug via twin-screw melt coating and granulation.

Int J Pharm

December 2024

Chemical and Biochemical Engineering, Rutgers University, 98 Brett Road, Piscataway, NJ 08854, USA. Electronic address:

Favipiravir, a high dose antiviral drug effective for oral treatment for COVID-19, with poor water solubility is formulated using a simple, low-cost melt coating and granulation methodology. High-dose (82.5 % w/w API) tablets (600 mg and 800 mg) with desired release profiles are developed while minimizing excipient burden.

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Introduction: The aim of the study was to investigate the caries-preventive effect of fluoride-free toothpastes, containing either herbal agents or (nano-)hydroxyapatite.

Methods: Bovine dentin specimens each having a sound (ST) and a demineralized area (DT) were prepared and randomly allocated to eleven groups (n = 187). Treatments during pH cycling (28 days; 6 × 120 min demineralization/day) were brushing 2×/day with 0 ppm F- [NaF0], 500 ppm F- [NaF500], 1,100 ppm F- [NaF1100], grape seed extract [GSE], (nano-)hydroxyapatite, melaleuca oil [MO1, MO2, MO-CU], and propolis + myrrh [PM1, PM2] containing dentifrices.

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Introduction: Disulfiram (DSF) reduces insulin resistance and weight gain in obese mice. However, the effect on adipose tissue is unexplored due to their high instability under physiological conditions, limiting clinical applications. Thus, it is meaningful to develop a DSF carrier for sustained release to adipose tissue.

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Rapid Method for Estimating Polyhydroxybutyrate Accumulation in Bacteria Using Sodium Hypochlorite.

Bio Protoc

December 2024

Instituto de Investigaciones Biológicas, CONICET - Universidad Nacional de Mar del Plata, Buenos Aires, Argentina.

This protocol outlines the use of the previously described sodium hypochlorite extraction method for estimating the accumulation of polyhydroxybutyrate (PHB) in bacteria. Sodium hypochlorite (NaClO) is widely used for PHB extraction as it oxidizes most components of the cells except PHB. We assessed the feasibility of using NaClO extraction for the estimation of PHB accumulation in bacterial cells (expressed as a percentage w/w).

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Corn wet milling (CWM) and corn starch flash drying processing conditions reduce undesirable microorganisms, such as Salmonella. Finished products are historically safe, with intrinsic properties such as low water activity inhibiting microbial growth. Corn processors could use quantified levels of reduction in this study of Salmonella surrogate Enterococcus faecium (E.

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