Parasitic Arthropods of Soricinae Shrews in North-Eastern Poland.

The study of the ectoparasite fauna of the insectivores-, , , and (subfamily Soricinae)-was carried out in three locations in Poland: Białowieża National Park, Kosewo Górne in the Masurian Lake District, and in vicinity of Warsaw. Three species of Ixodidae ticks, eleven species of fleas, and four species of mites from the order Mesostigmata were noted. The most numerous ectoparasites are ticks (larvae), (nymphs), and fleas , , and .

Increasing Prevalence of Artemisinin-Resistant HRP2-Negative Malaria in Eritrea.

Background: Although the clinical efficacy of antimalarial artemisinin-based combination therapies in Africa remains high, the recent emergence of partial resistance to artemisinin in on the continent is troubling, given the lack of alternative treatments.

Methods: In this study, we used data from drug-efficacy studies conducted between 2016 and 2019 that evaluated 3-day courses of artemisinin-based combination therapy (artesunate-amodiaquine or artemether-lumefantrine) for uncomplicated malaria in Eritrea to estimate the percentage of patients with day-3 positivity (i.e.

Distribution of large lungworms (Nematoda: Dictyocaulidae) in free-roaming populations of red deer (L.) with the description of n. sp.

Lungworms of the genus are causative agents of parasitic bronchitis in domestic and wild ungulates. This study investigates the distribution, morphology and genetic diversity of and a new lungworm species, n. sp.

Exploring rigid-backbone protein docking in biologics discovery: a test using the DARPin scaffold.

Accurate protein-protein docking remains challenging, especially for artificial biologics not coevolved naturally against their protein targets, like antibodies and other engineered scaffolds. We previously developed ProPOSE, an exhaustive docker with full atomistic details, which delivers cutting-edge performance by allowing side-chain rearrangements upon docking. However, extensive protein backbone flexibility limits its practical applicability as indicated by unbound docking tests.

Relative effects of urbanisation, deforestation, and agricultural development on mosquito communities.

Context: Despite numerous studies that showed negative effects of landscape anthropisation on species abundance and diversity, the relative effects of urbanisation, deforestation, and agricultural development as well as the spatial extent at which they act are much less studied. This is particularly the case for mosquitoes, which are the most important arthropods affecting human health.

Objectives: We determined the scale of effect of these three landscape anthropisation components on mosquito abundance and diversity.

COVID-19 morbidity in lower versus higher income populations underscores the need to restore lost biodiversity of eukaryotic symbionts.

The avoidance of infectious disease by widespread use of 'systems hygiene', defined by hygiene-enhancing technology such as sewage systems, water treatment facilities, and secure food storage containers, has led to a dramatic decrease in symbiotic helminths and protists in high-income human populations. Over a half-century of research has revealed that this 'biota alteration' leads to altered immune function and a propensity for chronic inflammatory diseases, including allergic, autoimmune and neuropsychiatric disorders. A recent Ethiopian study (EClinicalMedicine 39: 101054), validating predictions made by several laboratories, found that symbiotic helminths and protists were associated with a reduced risk of severe COVID-19 (adjusted odds ratio = 0.

The Tapeworm as an Important Model Organism in the Experimental Parasitology of the 21st Century.

The tapeworm is a common parasite of the small intestine in rodents but it can also infect humans. Due to its characteristics and ease of maintenance in the laboratory, is also an important model species in studies of cestodiasis, including the search for new drugs, treatments, diagnostics and biochemical processes, as well as its host-parasite interrelationships. A great deal of attention has been devoted to the immune response caused by in the host, and several studies indicate that infection with can reduce the severity of concomitant disease.

Vivax malaria in Duffy-negative patients shows invariably low asexual parasitaemia: implication towards malaria control in Ethiopia.

Background: The increase in detections of Plasmodium vivax infection in Duffy-negative individuals in Africa has challenged the dogma establishing the unique P. vivax Duffy Binding Protein-Duffy antigen receptor for chemokines (PvDBP-DARC) pathway used by P. vivax merozoites to invade reticulocytes.

Repurposing of MitoTam: Novel Anti-Cancer Drug Candidate Exhibits Potent Activity against Major Protozoan and Fungal Pathogens.

Many of the currently available anti-parasitic and anti-fungal frontline drugs have severe limitations, including adverse side effects, complex administration, and increasing occurrence of resistance. The discovery and development of new therapeutic agents is a costly and lengthy process. Therefore, repurposing drugs with already established clinical application offers an attractive, fast-track approach for novel treatment options.

Occurrence of chosen parasitic protozoa of roe deer (Capreolus capreolus) and red deer (Cervus elaphus) in Poland: a current review.

Both roe deer (Capreolus capreolus) and red deer (Cervus elaphus) are wild ruminants that are present in large numbers in Poland. Although both are very often infected with parasitic protozoa, the species composition of these parasites and their prevalence are relatively poorly known. The aim of the present work is to gather existing data on the occurrence and species diversity of parasitic protozoa of the genus Eimeria, Babesia, Theileria, Giardia, Cryptosporidium and family Sarcocystidae in red deer and roe deer in Poland and compare the findings with those from other European countries.

Infection with intestinal helminth (Hymenolepis diminuta) impacts exploratory behavior and cognitive processes in rats by changing the central level of neurotransmitters.

Parasites may significantly affect the functioning of the host organism including immune response and gut-brain-axis ultimately leading to alteration of the host behavior. The impact of intestinal worms on the host central nervous system (CNS) remains unexplored. The aim of this study was to evaluate the effect of intestinal infection by the tapeworm Hymenolepis diminuta on behavior and functions of the CNS in rats.

An attempt to deworm European bison (Bison bonasus) in the European Bison Breeding Center of Białowieża National Park with Alphalben (albendazole).

Parasitic infections are one of the most important factors affecting the health and condition of wild ruminants, including bison, particularly those kept in closed breeding, and regular deworming is important. The aim of this study was to investigate the effectiveness of deworming European bison in BNP (Białowieża National Park) reserves with Alphalben (albendazole). The drug was administered orally at a dose of 15 mg/kg body weight.

Occurrence of spp. in red foxes and wolves in the protected area of the Tatra National Park in southern Poland - a threat to human health.

Introduction: s has been endemic in red foxes in eastern and central parts of Europe, and s. l. identified in wolves in some countries.

Effect of ocular demodicosis on the stability of the tear film and the tear break up time.

The aim of the study was to analyze the correlation between the presence of Demodex mites in the hair follicles of patients' eyelashes and the stability and break up time of the tear film assessed with the Non-Invasive Tear Break Up Times (NIBUT) method. 319 patients were included in the study (195 women, 124 men). The patients were divided into two groups: those with Demodex infestation and without visible symptoms of eyelid or eye surface diseases, and asymptomatic non-infested patients.

Satellite-Like W-Elements: Repetitive, Transcribed, and Putative Mobile Genetic Factors with Potential Roles for Biology and Evolution of Schistosoma mansoni.

A large portion of animal and plant genomes consists of noncoding DNA. This part includes tandemly repeated sequences and gained attention because it offers exciting insights into genome biology. We investigated satellite-DNA elements of the platyhelminth Schistosoma mansoni, a parasite with remarkable biological features.

Self-Patterning Polyelectrolyte Multilayer Films: Influence of Deposition Steps and Drying in a Vacuum.

Typically, laterally patterned films are fabricated by lithographic techniques, external fields, or di-block copolymer self-assembly. We investigate the self-patterning of polyelectrolyte multilayers, poly(diallyldimethylammonium) (PDADMA)/poly(styrenesulfonate) (PSS). The low PSS molecular weight ((PSS) = 10.

Helminth Assemblages of the Antarctic Black Rockcod, Notothenia coriiceps (Actinopterygii: Nototheniidae) in Coastal Waters near Galindez Island (Argentine Islands, West Antarctic): Temporal Changes in the Endoparasite Community.

Purpose: Analysis and comparison of the helminth assemblages in Antarctic rockcod Notothenia coriiceps collected near the UAS "Akademik Vernadsky" (Argentine Islands, West Antarctica) in 2002 and 2014-2015 were performed to characterise the parasite community and investigate the temporal changes in helminth assemblages and infection parameters.

Methods: All specimens of N. coriiceps (n = 194) were caught at depths of 10-30 m.

Clinical Characteristics of Patients with Tick-Borne Encephalitis (TBE): A European Multicentre Study from 2010 to 2017.

Tick-borne encephalitis (TBE) virus is a major cause of central nervous system infections in endemic countries. Here, we present clinical and laboratory characteristics of a large international cohort of patients with confirmed TBE using a uniform clinical protocol. Patients were recruited in eight centers from six European countries between 2010 and 2017.

Prevalence of antibodies in wild boar (Sus scrofa) from Strzałowo Forest Division, Warmia and Mazury Region, Poland.

Introduction And Objective: Toxoplasmosis is an important zoonosis caused by a protozoan, . Raw or undercooked venison may be a source of infection in humans. The aim of the study was to determine the prevalence of antibodies in wild boar from the Strzałowo Forest Division of the Warmia and Mazury Region of Poland.

Biodiversity of lung helminths in terrestrial mammals from Eastern Europe.

This review provides the results of many years of original studies of the authors published in different journals and compilations taking into account an analysis of literature data. The studies on biological diversity of lung helminths of terrestrial mammals were performed by the authors in Armenia, Bulgaria and Poland. Literature data on European Russia were also taken into account.

Blastocystis isolates from a dog and their owners presenting with chronic diarrhoea. Dogs as reservoirs of Blastocystis: research in Poland and worldwide.

Blastocystis cf. hominis is an unicellular protozoan parasite commonly found in the gastrointestinal tract of humans and animals. Blastocystis is characterized by high morphological and genetic diversity.

Wenyonia gracilis sp. n. (Cestoda: Caryophyllidea) from Synodontis zambezensis (Siluriformes: Mochokidae): the first native caryophyllidean tapeworm from southern Africa.

Parasitological examination of freshwater fishes of the Phongolo River in north-eastern KwaZulu-Natal, South Africa resulted in the discovery and morphological and molecular characterisation of a new species of Wenyonia Woodland, 1923 (Cestoda: Caryophyllidea). The new species from the plain squeaker, Synodontis zambezensis Peters (Siluriformes: Mochokidae), is morphologically most similar to Wenyonia acuminata Woodland, 1923, a species reported from three species of Synodontis in north-eastern, western and central Africa (Sudan, Nigeria, Democratic Republic of the Congo). Both these species are markedly different from congeners by having a nematoform body and a digitiform scolex.