320 results match your criteria: "Vydehi institute of medical sciences and research centre[Affiliation]"

Background And Aim: Accurate interpretation of post-treatment imaging in head and neck malignancies poses a challenge due to treatment sequelae. Magnetic resonance (MR) perfusion helps in this scenario by evaluating the hemodynamic characteristics of lesions. This study aimed to elucidate the diagnostic efficacy of dynamic contrast-enhanced (DCE)-MR perfusion imaging in detecting recurrence in patients after they underwent definitive treatment for head and neck tumors.

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Background: Despite the availability of a wide range of agents, no single treatment exists for the management of radiation-induced oral mucositis, in patients, with head and neck malignancies, on radical chemoradiation; a debilitating and limiting sequela. Human placental extract is one option that has been proposed.

Aims And Objectives: This study aimed at evaluating the therapeutic benefits of human placental extract (Placentrex) in the management of radiation-induced oral mucositis in patients on curative intent treatment for head and neck cancers with concurrent chemoradiation, and to compare the observations with other conventional approaches.

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Diagnostic performance of various imaging modalities in localizing ectopic ACTH syndrome: A systematic review.

Ann Endocrinol (Paris)

December 2024

Department of Endocrinology, Seth GS Medical College, KEM Hospital, 400012 Parel, Mumbai, India. Electronic address:

Article Synopsis
  • * Sensitivity for tumor identification was similar across contrast-enhanced CT (CECT) and two types of PET scans (SSTR and FDG), but notably low for DOPA-PET, while CECT showed better results for specific tumors like Thymic NET.
  • * SSTR-PET/CT is recommended as the preferred imaging method due to its lower false positive rate, although a significant number of tumors (about 25%) in patients remain undetected with current methods, indicating a need for further research.
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Thymoma and thymic carcinomas are a few of the rarest malignancies seen in humankind. They are mostly seen in the Asian population, many of which are reported in the Southeast Asia region like Japan, China, Vietnam, etc. They usually can be a sequela of other underlying conditions such as myasthenia gravis or some unknown mutations that express later in life.

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Article Synopsis
  • Dengue fever can cause low platelet counts (thrombocytopenia), which increases the risk of bleeding and death.
  • A 35-year-old man exhibited dengue symptoms, including fever and nosebleeds, and had a significant drop in platelet count.
  • The use of papaya leaf extract helped improve his platelet count from 30,650 to 120,320 over 14 days, highlighting its potential therapeutic benefits in managing dengue.
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Eggs, which are often considered a complete food, have recently been scrutinized by the media as a potential cause of cardiovascular disease. However, the media hasn't shown the same enthusiasm for processed foods high in fructose, the consumption of refined cooking oil, seed oils, and carbohydrate-rich meals, the connection between these factors and metabolic diseases, or the potential long-term impacts on population comorbidities, as they have for criticizing egg yolks as a cause for cardiovascular disease in recent times. This review investigates the relationship between eggs and lipid levels, glucose levels, atherosclerosis, and antioxidant properties, as well as comparing them to cholesterol-free egg controls.

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Introduction: Pituitary apoplexy (PA) in Cushing's disease (CD) is rare with data limited to case reports/series.

Methods: We retrospectively reviewed case records of PA in CD managed at our center from 1987 to 2023 and performed a systematic literature review.

Results: We identified 58 patients (44 females), including twelve from our center (12/315 CD, yielding a PA prevalence in CD of 3.

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Article Synopsis
  • HIV weakens the immune system, making it crucial to monitor a patient's immune status to assess disease progression and treatment follow-up.
  • Traditional CD4 count tests are expensive and technically demanding, prompting the exploration of urinary free light chains (FLCs) as a cost-effective alternative for monitoring HIV severity and therapy responses.
  • A study showed that urinary kappa light chain levels were significantly higher in HIV patients compared to healthy controls and correlated with disease progression, suggesting that urinary FLC measurements could complement serum tests when flow cytometry is unavailable.
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Thyroid abscess is a rare occurrence and is characterized by an accumulation of pus within the thyroid gland. It most commonly forms as a sequela of acute suppurative thyroiditis, and it presents as a painful swelling of the anterior neck with fever. Patients may also develop referred ear pain and compressive symptoms such as difficulty breathing and swallowing as the abscess enlarges.

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Leprosy is a chronic granulomatous infection that primarily affects developing and underdeveloped countries. Co-infection with the hepatitis B virus can complicate its natural course by altering the host immune system response and thereby the disease outcomes. Early detection and treatment of the disease is thus imperative for preventing debilitating deformities.

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Resistance exercise training (RET) is used to improve muscular strength and function. This study tested the hypothesis that RET alongside daily supplementation of a and extract blend (SMI) would augment bench press (BP) and leg extension (LE) strength and repetitions to failure (RTF) compared to RET alone. Ninety-nine men (age 22 ± 3) completed the trial after randomization into one of four groups: (A1) 425 mg SMI plus one RET set; (A2) 850 mg SMI plus one RET set; (P1) placebo plus one RET set; and (P2) placebo plus two RET sets.

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Introduction: This study evaluates feasibility of telemedicine to deliver diabetic care among different regions of the country.

Materials And Methods: Medical interns affiliated with Rotaract Club of Medicrew (RCM) organized a Free Diabetes Screening Camp called " at multiple sites across the country. Of all beneficiaries of the camp >18 years of age, patients previously diagnosed with diabetes and undiagnosed patients with a random blood sugar level of more than 200 mg/dL were interviewed regarding their knowledge, attitude, and practice regarding diabetes care and preparedness and vigilance to receiving care through telemedicine.

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Background In this study, researchers investigated non-invasive methods for analyzing creatinine levels by using saliva to address the need for frequent phlebotomy in chronic kidney disease (CKD) patients, which can damage their veins due to repeated blood withdrawals for creatinine level assessments. Methods This is a cross-sectional study in a tertiary healthcare setting conducted on 50 patients diagnosed with CKD. After collecting serum and salivary creatinine, we used Pearson correlation to assess the correlation between the two factors.

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Objective The objective of this study was to evaluate errors in the use of metered-dose inhalers (MDIs) among patients diagnosed with asthma or chronic obstructive pulmonary disease (COPD). Additionally, we aimed to assess improvements following corrective interventions. Settings and design This cross-sectional study was done by simple random sampling.

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Background Oncological surgeries pose an elevated risk of surgical site infections (SSIs) due to their complexity and various associated treatments, impacting patient outcomes and healthcare costs. This has prompted a focus on advanced wound dressings that provide microbial protection, exudate absorption, and improved product performance, enhancing patient satisfaction. Our study aimed to compare the efficacy and safety of Theruptor NXT with the current standard of care (SOC) practice involving cotton/povidone/micropore dressings in the postoperative wound management of oncological surgeries.

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Glucocorticoid resistance syndrome is a rare disorder with no genetically proven cases reported from India; in addition, there are no descriptions available regarding its management during pregnancy. A 27-year-old woman, hypertensive since the age of 17 years, presented with hypokalemic paresis. She reported regular menses and acne.

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Allergy and immunological disorders like autoimmune diseases are vastly prevalent worldwide. These conditions account for a substantial amount of personal and social burden. Such illnesses have lengthy, uncertain, and spotted courses with unpredictable exacerbations.

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Article Synopsis
  • The study investigates the prevalence of malignancy in Bethesda II thyroid nodules in South India, revealing an 8.5% malignancy rate among the 563 patients studied.
  • Key predictors of malignancy include multi-nodularity, thyroid calcification, the presence of suspicious cervical lymph nodes on ultrasound, and a history of thyrotoxicosis, although age, gender, and maximum nodule size were not linked to malignancy.
  • The findings suggest a need for more thorough assessments of thyroid nodules, especially those classified as Bethesda II, to better understand the associated malignancy risks.
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Article Synopsis
  • Thyrotoxicosis is a common condition in endocrine practice, primarily caused by Graves' disease and subacute thyroiditis; differentiating between the two is crucial for proper treatment.
  • The study evaluates TSH receptor antibodies (TSHrAb) as a diagnostic tool for distinguishing these conditions in the Indian population, especially since conventional tests like 99mTc thyroid scintigraphy are often unavailable in smaller cities.
  • Results show that TSHrAb has a high diagnostic accuracy (AUC: 0.9) compared to other methods, making it a reliable option for distinguishing Graves' disease from subacute thyroiditis.
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Introduction Anesthesia is an important specialty in the medical field responsible for caring for patients before, during, and after operations. It involves monitoring vital signs, managing pain levels, and regulating consciousness. There are various subspecialties of anesthesia, including general anesthesia, intensive care medicine, cardiac anesthesia, and pain medicine, among others.

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Aim: The study evaluated the antifungal activity of sodium hypochlorite (NaOCl), calcium hypochlorite (Ca(OCl)), and modified salt solution (MSS) assisted with passive ultrasonic irrigation against .

Materials And Methods: One hundred and thirty-six single-rooted premolars were decoronated and enlarged up to a file #45, autoclaved, inoculated with . , and incubated for 72 h.

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Morphometry of pinna may change following ear surgeries. This study gives information about postoperative changes following ear surgeries. This study aims to measure the variation of ear morphology following surgery and to correlate the type of surgery with post-operative variations.

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Background: Immunization is a cost-effective weapon against vaccine preventable diseases. Children of migrant workers suffer from lack of immunization because of frequent shift of places, poor knowledge, and low socioeconomic status. To assess the immunization status of children 12-36 months of age of migrant workers and factors associated it.

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Objective: Lipoid congenital adrenal hyperplasia (LCAH) is caused by mutations in STAR. A systematic review of phenotype-genotype correlation and data on testicular histology in LCAH patients is unavailable. We aim to describe our experience and provide phenotype-genotype correlation.

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