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Aim: The aim of this study was to compare the efficacy of newly developed irrigation systems, i.e., XP-endo Finisher file (XP-endo), EndoActivator (EA), and Endo-Irrigator Plus (EI) with gold standard passive ultrasonic irrigation (PUI) tip and in removal of calcium hydroxide (CH) from single-rooted teeth with artificial simulated internal resorption cavities.

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