3 results match your criteria: "Vrije University Medical Center (VUMC)[Affiliation]"

Background And Aim: Sodium-glucose cotransporter-2 inhibitors (SGLT2i) induce less weight loss than expected. This may be explained by SGLT2i-induced alterations in central reward and satiety circuits, contributing to increased appetite and food intake. This hyperphagia may be specific to high-calorie foods.

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Predictors of the onset of manic symptoms and a (hypo)manic episode in patients with major depressive disorder.

PLoS One

June 2015

University of Groningen, University Medical Center Groningen (UMCG), Interdisciplinary Center Psychopathology and Emotion Regulation (ICPE)/University Center Psychiatry (UCP), Groningen, The Netherlands; Vrije University Medical Center (VUMC), Department of Psychiatry and Extramuraal Geneeskundig Onderzoek (EMGO) Institute for Health and Care Research, Amsterdam, The Netherlands; Leiden University Medical Center, Department of Psychiatry, Leiden, The Netherlands.

Objective: One third of patients with a major depressive episode also experience manic symptoms or, even, a (hypo)manic episode. Retrospective studies on the temporal sequencing of symptomatology suggest that the majority of these patients report depressive symptoms before the onset of manic symptoms. However, prospective studies are scarce and this study will, therefore, prospectively examine the onset of either manic symptoms or a (hypo)manic episode in patients with a major depressive disorder.

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Preservation of diastolic function in monocrotaline-induced right ventricular hypertrophy in rats.

Am J Physiol Heart Circ Physiol

September 2007

Department of Anesthesiology, Institute for Cardiovascular Research-Vrije University (ICaR-VU), Vrije University Medical Center (VUMC), Amsterdam, The Netherlands.

Article Synopsis
  • During ischemic heart diseases and heart failure, the depletion of energy in the heart muscle negatively impacts function.
  • D-Ribose and Folic Acid were given to Wistar rats to study their effects on cardiac health during induced right ventricular hypertrophy.
  • Results showed that while D-Ribose-Folic Acid treatment helped maintain energy levels and improve heart function in comparison to a placebo, it did not completely restore creatine levels or fully normalize systolic function.
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