2,212 results match your criteria: "Vocal Cord Dysfunction"

Introduction: There is a paucity of literature on pre-adolescent paradoxical vocal fold motion (PVFM), PVFM is a sub-type of inducible laryngeal obstruction. Studies typically focus on older patients, however the discovery of this entity in pre-adolescent pediatric patients has led to more questions about how this entity manifests differently and is treated differently in younger populations. Initially considered psychosomatic and commonly mistaken for asthma, PVFM etiology is now thought to be associated underlying neurologic conditions and may have irritant triggers with proposed mechanisms related to laryngeal hypersensitivity.

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[Analysis of clinical characteristics of amyotrophic lateral sclerosis patients initially diagnosed with abnormal laryngeal function].

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi

December 2024

Department of Voice Medicine, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen Key Laboratory of Voice Medicine, Xiamen361004, China.

To study the laryngeal functional characteristics of patients with amyotrophic lateral sclerosis (ALS)disease diagnosed at the voice clinic. A retrospective analysis(case series study) was conducted on the laryngeal functional characteristics of 7 patients [2 males, 5 females, age ranged from 43 to 76(60.85±13.

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Autoimmune encephalitis is a disorder characterized by an autoantibody-mediated process that leads to brain inflammation. It is associated with neurological symptoms including cognitive issues, psychiatric problems, seizures, and autonomic dysfunctions. Anti-leucine-rich glioma-inactivated 1 limbic encephalitis (anti-LGI1 LE) is a rare type of autoimmune LE with a unique presentation, comprising neuropsychiatric disturbances, sleep disorders, and faciobrachial dystonic seizures (FBDS).

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Repair of aortic coarctation in neonates less than two kilograms.

Interdiscip Cardiovasc Thorac Surg

December 2024

Department of Cardiac Surgery, Bristol Royal Hospital for Children, University of Bristol, Bristol, UK.

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Peripheral airways dysfunction measured by oscillometry differentiates asthma from inducible laryngeal obstruction.

Respir Med

December 2024

Division of Pulmonary and Critical Care Medicine, University of Rochester School of Medicine and Dentistry, 601 Elmwood Ave, Rochester, NY, 14642, USA; Mary Parkes Center for Asthma, Allergy & Pulmonary Care, 400 Red Creek Drive, Suite 110, Rochester, NY, 14623, USA. Electronic address:

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Introduction: Vocal cord dysfunction (VCD) is a complex disorder characterized by episodic adduction of the vocal folds during inspiration and expiration, which can lead to dyspnea, wheezing, cough, and acute-onset respiratory distress. Currently, there is a lack of standardized criteria among treating physicians across multiple disciplines, including otolaryngologists, pulmonologists, allergists, and speech and language pathologists, for diagnosis and treatment of VCD, although laryngeal-respiratory retraining therapy (LRT) has emerged as the preferred treatment modality.

Objective: In the present study, we examined the efficacy of LRT in patients presenting with a clinical diagnosis of VCD in the presence and absence of laryngeal adduction on laryngoscopy.

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Study Objectives: Multiple system atrophy (MSA) is a rare neurodegenerative disorder characterized by autonomic dysfunction associated with a combination of cerebellar, parkinsonian, or pyramidal signs. Sleep-disordered breathing (SDB) such as stridor, obstructive sleep apnea (OSA) and central sleep apnea (CSA) are common in MSA and can impact survival. Several studies have evaluated treatment modalities.

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Article Synopsis
  • The study analyzes the acoustic features of patients with hypopharyngeal cancer who also have vocal cord dysfunction, comparing two groups based on vocal cord activity: one with dysfunction and the other with normal function.
  • Significant findings show that lesions in the experimental group are more common on the inner wall of the piriform fossa, with a statistically meaningful difference, while vocal parameters like sound intensity showed no significant difference between both groups.
  • Stroboscopic laryngoscopy results indicated higher rates of glottic insufficiency and asymmetric arytenoid cartilage in the experimental group, although both groups maintained normal mucosal wave patterns on the vocal cords.
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Severe postoperative negative pressure pulmonary edema: a case report.

BMC Anesthesiol

November 2024

Department of Anesthesiology and Operative Intensive Care Medicine, University Hospital of Cologne, Kerpener Str. 62, Cologne, 50937, Germany.

Article Synopsis
  • Postoperative negative pressure pulmonary edema (NPPE) can affect any patient following general anesthesia, often triggered by factors like laryngospasm, but it is usually mild and reversible.* -
  • This case highlights a severe instance of NPPE in a 62-year-old man who developed acute respiratory distress syndrome (ARDS) after laryngospasm during elective surgery, possibly linked to an allergic reaction.* -
  • The patient improved significantly with advanced ventilation techniques and was discharged from intensive care after 10 days, underlining the importance of recognizing and managing NPPE as a potential complication of anesthesia.*
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Asthma is a chronic lung condition that may be affected by numerous medical comorbidities. Such comorbidities can influence the presentation and even the severity of asthma. Alternatively, asthma may be misdiagnosed as a comorbidity when symptoms overlap.

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Optimizing the Diagnosis and Management of Pediatric Inducible Laryngeal Obstruction.

Laryngoscope

October 2024

Division of Otolaryngology-Head and Neck Surgery, Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.

Article Synopsis
  • Pediatric inducible laryngeal obstruction (ILO) is hard to diagnose and can take a long time for doctors to figure out what's wrong.
  • A study looked at 78 kids with ILO from 2015 to 2023, finding that most of them were girls around 14 years old and many thought they had asthma.
  • Management mostly included breathing exercises, which worked for some, but many kids still had symptoms after treatment, with it taking about a year on average for things to get better.
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Outcomes of Patients Undergoing Surgery for Complete Vascular Rings.

J Am Coll Cardiol

October 2024

Harvard Medical School, Boston, Massachusetts, USA; Department of Cardiac Surgery, Boston Children's Hospital, Boston, Massachusetts, USA. Electronic address:

Article Synopsis
  • This study investigated the outcomes of complete vascular ring surgeries in children, analyzing their clinical presentation, diagnostic procedures, surgical methods, and follow-up results.
  • Over a span of more than 33 years, 515 patients were studied, with the majority diagnosed with right aortic arch conditions and very few complications reported post-surgery.
  • At follow-up, an impressive 94.7% of patients experienced complete symptom resolution, indicating that these surgeries are effective with a low chance of needing further operations due to recurring symptoms.
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  • * A case study is highlighted involving a 56-year-old woman with breast cancer whose chemoport catheter migrated into her heart, leading to dysfunction during chemotherapy, which was detected through chest X-ray.
  • * The migration was successfully managed using a snare technique, emphasizing the importance of fast detection and collaboration among healthcare professionals when complications arise.
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  • Multiple system atrophy (MSA) is a serious neurodegenerative disease that can cause symptoms like vocal cord paralysis (VCP), Parkinsonism, and other issues.
  • COVID-19 has been linked to neurological problems and can worsen VCP even in patients without prior neurological conditions.
  • The text discusses two MSA patients whose VCP worsened after COVID-19, necessitating emergency tracheostomies, highlighting the importance of preventing COVID-19 in these patients and monitoring for any deterioration.
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  • The study investigates how the severity of dysphagia (difficulty swallowing) affects the survival rates of patients with multiple system atrophy (MSA), focusing on both MSA-C (cerebellar ataxia) and MSA-P (parkinsonism).
  • It includes 297 patients, with findings showing that those who developed dysphagia within three years of symptom onset had a significantly shorter survival time compared to those without dysphagia.
  • The results indicate that dysphagia severity (measured by the Hyodo score) correlates with survival in both types of MSA, suggesting it is a crucial predictor of patient outcomes regardless of the subtype.
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Age differences in inducible laryngeal obstruction in adult populations.

Ann Allergy Asthma Immunol

November 2024

Division of Allergy and Immunology, College of Medicine, University of Nebraska Medical Center, Omaha, Nebraska.

Article Synopsis
  • The study aimed to investigate how inducible laryngeal obstruction (ILO) symptoms vary among adults of different ages, using a sample of 67 patients over 16 years old confirmed to have ILO.
  • Results showed that adults under 50 reported significantly more symptoms like shortness of breath and chest tightness compared to those 50 and older.
  • The findings suggest that older adults might have less obvious ILO symptoms and anxiety, indicating a need for increased awareness and evaluation in this age group.
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  • Exercise-induced bronchoconstriction (EIB) commonly affects individuals with asthma, leading to symptoms like coughing and wheezing after physical activity, though its exact mechanisms are still not fully understood.
  • To diagnose EIB, healthcare providers must rule out other conditions through a combination of detailed medical history, clinical examination, spirometry, and specific exercise tests, like the treadmill running test for children over 8 years old.
  • Treatment strategies include medications, primarily short-acting beta-agonists before exercise and inhaled corticosteroids for more severe cases, along with behavioral approaches such as warming up and maintaining good air quality during exercise.
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  • - The recurrent laryngeal nerve (RLN) can be injured during neck surgery, leading to serious issues with vocal cord function, but using electromyography (EMG) helps identify the nerve and decrease the risk of damage.
  • - Improper placement of specialized EMG endotracheal tubes (ETTs) can lead to unreliable signals, so a new educational protocol was created to standardize their placement and improve RLN monitoring reliability.
  • - Data from surgeries before and after the protocol showed a significant drop in alerts for ETT malposition, highlighting improved accuracy and a sustained reduction in nerve injury risks through ongoing education for anesthesia staff.
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  • The study aimed to assess complications and mortality related to vagus nerve stimulation (VNS) used for drug-resistant epilepsy treatment.
  • A total of 117 VNS procedures were analyzed over 23 years, revealing common early complications like hoarseness and cough, while fewer severe complications were noted, particularly among children with intellectual disabilities.
  • Despite some risks and late complications, VNS therapy appears mostly safe for long-term use, with a suggestion that it may reduce the incidence of sudden unexpected death in epilepsy (SUDEP) over time.*
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  • A new microscopic diagnostic sign for asphyxial drowning has been discovered in white male rats, indicating changes in the laryngeal mucosa.
  • The research showed significant hyperplasia (increase in the number of cells) of serotonin-containing APUD-cells in the larynx when rats experienced acute anoxia, compared to healthy controls.
  • These changes may trigger laryngospasm, which helps prevent water from entering the airways during drowning, suggesting this hyperplasia can be a useful diagnostic criterion in research on drowning.
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Background: Laryngospasm is sustained closure of the airways and can be a life-threatening condition. Magnesium sulphate is postulated to reduce the incidence of laryngospasm if administered peri-operatively. This systematic review and meta-analysis was performed to assess the efficacy of magnesium sulphate in preventing peri-operative laryngospasm in paediatric patients undergoing non-cardiac surgery.

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