4 results match your criteria: "Virtua Health College of Medicine and Life Sciences of Rowan University[Affiliation]"

Medial prefrontal cortex to nucleus reuniens circuit is critical for performance in an operant delayed nonmatch to position task.

Neurobiol Learn Mem

November 2024

Department of Cell Biology and Neuroscience, Rowan-Virtua School of Translational Biomedical Engineering and Sciences, United States; Rowan-Virtua School of Osteopathic Medicine, Virtua Health College of Medicine and Life Sciences of Rowan University, Stratford, NJ, 08084, United States. Electronic address:

Working memory refers to the temporary retention of a small amount of information used in the execution of a cognitive task. The prefrontal cortex and its connections with thalamic subregions are thought to mediate specific aspects of working memory, including engaging with the hippocampus to mediate memory retrieval. We used an operant delayed-non match to position task, which does not require the hippocampus, to determine roles of the rodent medial prefrontal cortex (mPFC), the nucleus reuniens thalamic region (RE), and their connection.

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Effects of sex and estrous cycle on action-outcome contingencies.

Behav Brain Res

February 2025

Department of Cell Biology and Neuroscience, Rowan-Virtua School of Translational Biomedical Engineering and Sciences, Virtua Health College of Medicine and Life Sciences of Rowan University, Stratford, NJ, United States; Rowan-Virtua School of Osteopathic Medicine, Virtua Health College of Medicine and Life Sciences of Rowan University, Stratford, NJ, United States. Electronic address:

Goal-directed and habitual-like behaviors are both necessary to efficiently and effectively navigate the environment. A dysregulation between these behaviors can lead to an overreliance on habitual-like behaviors and may contribute to symptoms experienced in some neuropsychiatric disorders such as substance use disorder. One behavioral task used to evaluate goal-directed and habitual-like behavior is an action-outcome task, contingency degradation, where an action (i.

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The Hedgehog (HH) pathway regulates embryonic development of anterior tongue taste fungiform papilla (FP) and the posterior circumvallate (CVP) and foliate (FOP) taste papillae. HH signaling also mediates taste organ maintenance and regeneration in adults. However, there are knowledge gaps in HH pathway component expression during postnatal taste organ differentiation and maturation.

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Article Synopsis
  • * Whole exome sequencing (WES) on family members revealed a specific mutation (c.195del/p.(Thr66ProfsTer55)) that linked with affected individuals, along with two additional variants in SSX1 and USP27X genes.
  • * RNA sequencing showed 14 differentially expressed genes related to neurological disorders in the affected males, reinforcing the connection between the DLG3 mutation and the observed clinical issues in the family.
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