Cryotherapy for removal of an embedded, partially covered esophageal stent.

Video 1Cryotherapy for removal of an embedded, partially covered esophageal stent.

Referral process to further evaluate poor sleep in breast cancer survivors.

Objective: Breast cancer survivors (BCS) are twice as likely to report symptoms of poor sleep as those without cancer. However, sleep disorders are under-assessed and under-treated among BCS. The purpose of this study was to determine the portion of BCS who completed referral visits to a sleep specialist and identify the acceptability, facilitators, and barriers to the screening and referral process.

Dealing with prognostic uncertainty: the role of prognostic models and websites for patients with advanced cancer.

Purpose Of Review: To provide an updated overview of prognostic models in advanced cancer and highlight the role of prognostic calculators.

Recent Findings: In the advanced cancer setting, many important healthcare decisions are driven by a patient's prognosis. However, there is much uncertainty in formulating prognosis, particularly in the era of novel cancer therapeutics.

Reducing Variability in the Infant Sepsis Evaluation (REVISE): A National Quality Initiative.

Background: Substantial variability exists in the care of febrile, well-appearing infants. We aimed to assess the impact of a national quality initiative on appropriate hospitalization and length of stay (LOS) in this population.

Methods: The initiative, entitled Reducing Variability in the Infant Sepsis Evaluation (REVISE), was designed to standardize care for well-appearing infants ages 7 to 60 days evaluated for fever without an obvious source.

Treatment patterns and medication adherence among patients diagnosed with multiple myeloma and treated with panobinostat.

Aim: To examine real-world treatment patterns in multiple myeloma (MM) patients treated with panobinostat.

Materials & Methods: Using a US claims database, MM patients treated with panobinostat during 02/01/2015-01/31/2017 were evaluated. Lines of therapy, combination regimens, dosing and duration were measured.

Heme oxygenase-1 genetic variants and the conundrum of hyperbilirubinemia in African-American newborns.

Background: African-American (AA) infants are known to have, overall, lower bilirubin levels than infants of other ethnicities during their birth hospitalization. However, they are known to have a higher incidence of severe hyperbilirubinemia and are over represented in the US Kernicterus Registry. Heme oxygenase-1 (HO) is the rate limiting enzyme in heme metabolism leading to the equimolar production of bilirubin, carbon monoxide (CO) and free iron (Fe).