Prevalence and associated factors of uncontrolled blood pressure among hypertensive patients in a rural population of Salem, Tamil Nadu.

Introduction: Hypertension, a significant risk factor for cardiovascular diseases, is a prevalent public health concern globally. It imposes a substantial burden on healthcare systems, particularly in low and middle-income countries like India. Despite the availability of effective treatments, hypertension remains poorly controlled leading to increased morbidity and mortality.

Diosmin induces mitochondrial-mediated apoptosis and anti-inflammatory effects in Hep-2 cells: an integrated in vitro and in silico analysis.

The present study aims to explore the anticancer efficacy of Diosmin by inducing mitochondrial-mediated apoptosis in human epidermoid carcinoma cells (Hep-2). This is done by cell line assays and studying crucial inflammatory and apoptotic signaling molecules. The cytotoxicity property of Diosmin was evaluated by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay.

Modified Cajal's trichrome stain in oral squamous cell carcinoma.

Background: Modified Cajal's trichrome stain (MCTS) is a good differential stain that allows one to visibly distinguish between connective tissue and epithelial elements with different tonalities of colour.

Aim: Our study aims to evaluate and analyse the effectiveness of oral squamous cell carcinoma (OSCC) using MCTS.

Materials And Methods: A study was conducted retrospectively with 30 tissue blocks embedded in paraffin from cases of OSCC that have been confirmed by histopathology.

Professor Dr. Bangalore Krishnaswamy Venkataraman (1923-2018): An Icon and Pioneer of Oral Medicine in India.

Professor Dr. Bangalore Krishnaswamy Venkataraman, a pioneer in oral medicine, significantly shaped dental education and practice in India and beyond. Rising from humble beginnings, he became a leading authority in dentistry, particularly in oral medicine and radiology.

Lymphangioma Circumscriptum on the Buccal Mucosa: A Case Report of a Rare Entity.

Hamartomatous lymphatic channel proliferation causes lymphangiomas or microcystic lymphatic malformations (MLM). They are most commonly found in the head and neck, with oral occurrences a rarity. In this case, a 34-year-old woman presented with lymphangioma circumscriptum on the buccal mucosa, a condition that typically causes asymptomatic pebbly papules.

Comparative study of conventional exfoliative cytology and centrifuged liquid-based cytology in oral leukoplakia and oral squamous cell carcinoma patients.

Background: This study aims to compare the efficacy between conventional exfoliative cytology (EC) and centrifuged liquid-based cytology (CLBC) in control, leukoplakia, and oral squamous cell carcinoma (OSCC) patients. Oral leukoplakia and oral cancer require an early definitive diagnosis for better prognostic outcome. Oral EC, a minimally invasive technique that involves the examination of desquamated cells from the tissue surfaces used as a method of early diagnosis.

Shoulder girdle muscle abscess: Potential routes of spread and surgical management by a dual anterior approach.

Background: Spontaneous infections involving muscles in the shoulder girdle are uncommon conditions rarely reported in the literature. The large musculature of shoulder girdle, complex communicating spaces into the periscapular region, and late glenohumeral joint involvement can cause delay in diagnosis of infections involving muscular portion of rotator cuff. The method of surgical drainage with involvement of scapulothoracic and subscapular spaces and prognosis can be challenging.

Association of obesity and overweight with the risk of preeclampsia in pregnant women: an observational cohort study.

Background: According to the World Health Organization, obesity is considered a pervasive global epidemic with significant medical and social implications. In antenatal mothers, the prevalence varies from 40% in Western countries to 12% in India which leads to life-threatening complications-preeclampsia and eclampsia.

Aim: This study delves into the association between body mass index (BMI) and preeclampsia, among primi antenatal mothers with pregnancy-induced hypertension (PIH).

Association between PITX2 polymorphism and androgenetic alopecia in the Indian population.

Background Androgenetic alopecia, also known as male pattern baldness, is a common form of hair loss influenced by environmental, hormonal, and genetic factors. According to recent research, the PITX2 gene may play a key role in the pathophysiology of androgenetic alopecia (AGA). Objective This study examines the association between genetic variants of the PITX2 gene and AGA risk.

Hidden benefits of snail mucus: A natural skincare marvel.

Dear Editor, From a scientific perspective, snail mucus, or snail secretion filtrate (SSF), has emerged as a significant discovery in dermatology and regenerative medicine. Several studies on mucus composition have illuminated its features in recent years, yet much remains unexplored. High-quality snail mucus contains adequate levels of active substances (e.

Effect of proton pump inhibitors on susceptibility and melanogenesis of species.

Sporotrichosis is a subcutaneous infection caused by dimorphic species embedded in the clinical clade. Fungi have virulence factors, such as biofilm and melanin production, which contribute to their survival and are related to the increase in the number of cases of therapeutic failure, making it necessary to search for new options. Proton pump inhibitors (PPIs) have already been shown to inhibit the growth and melanogenesis of other fungi.

Psychological and socio-cultural factors affecting latrine ownership and usage in rural South India.

The levels of latrine utilization were lower than the levels of latrine ownership in rural areas owing to certain psycho-social barriers hindering latrine construction and consistent utilization. The study was aimed to identify the proportion of latrine construction and usage and to explore the psychological, socio-cultural and structural factors influencing latrine ownership and utilization. A community-based cross-sectional study was carried out at the four villages of Villupuram district for three months.

Predictors for diabetes and hypertension among bus drivers and conductors in South India.

Bus drivers and conductors are facing various health hazards due to stressful working conditions. They are exposed to various occupational hazards which lead to deterioration of their health over a period of time. Therefore, it is of interest to evaluate the prevalence of diabetes and hypertension among bus drivers and conductors and to determine the factors associated with diabetes and hypertension.

Machine Learning-Based Prediction of Cyclic Voltammetry Behavior of Substitution of Zinc and Cobalt in BiFeO/BiFeO for Supercapacitor Applications.

Artificial intelligence and machine learning have become indispensable tools across various disciplines in the present century. In that way, the role of artificial intelligence and machine learning in energy storage devices was investigated. As a preliminary study, the data derived from electrochemical studies were used for the prediction.

Role of Sticky Bone in the Management of Various Alveolar Bone Defects: A Systematic Review.

Aim: This systematic review aimed to evaluate the effectiveness of sticky bone in managing various alveolar bone defects, examining both its benefits and drawbacks.

Materials And Methods: The review adhered to PRISMA guidelines and employed a thorough search strategy using major databases, medical subject headings (MeSH) keywords, and Boolean operators. As a result, the systematic review identified 12 studies focusing on the efficacy of sticky bone in treating alveolar bone defects.

Engineering Whole-Cell Biosensors for Enhanced Detection of Environmental Antibiotics Using a Synthetic Biology Approach.

Bacterial Two component systems have evolved with many intricate sensory apparatuses for external stimuli like light, temperature, oxygen, pH and chemical compounds. Recent studies have shown the potential of two-component regulatory systems (TCSs) of bacteria in creating synthetic regulatory circuits for several applications. Antimicrobial resistance is increasing globally in both developing and developed countries and it is one of the foremost global threats to public health.

Noninvasive Biomarkers for Alcohol-Related Liver Disease-A Proteomic Related Preliminary Report.

Unlabelled: Increased alcohol intake over decades leads to progressive alcohol-related liver disease (ALD) and contributes to increased mortality. It is characterized by reduced platelet count. Platelets have a role in protecting vascular integrity and involved in liver regeneration.

Internet gaming disorder: The prevalence and associated gaming behavior, anxiety, and depression among 8-12-year-old children of private schools in Salem city, India.

Background: The escalating concern over Internet gaming disorder (IGD) among children underscores the urgency of comprehending its determinants and links to mental health, particularly for interventions targeting school-aged children.

Aim: This study aimed to evaluate the prevalence and determinants of IGD and its association with depression, anxiety, and behavior among 8-12-year-old children attending private schools in Salem city.

Settings And Design: A cross-sectional study involving 780 children aged 8-12 years from Salem district was conducted.

Comparative evaluation on surface nanohardness, surface microhardness, surface roughness, and wettability of plant-based organic nanoparticle reinforced polyetheretherketone as an implant material - An in vitro study.

Aim: Synthetic inorganic materials are commonly used as reinforcing agents in polyetheretherketone (PEEK) composite, whereas natural organic plant-based reinforcing agents are negligible. Surface hardness, roughness, and wettability are indicative factors of osseointegration behavior to be used as an implant material. This study evaluated micro surface hardness (MSH), nano surface hardness (NSH), surface roughness (SR), and contact angle (CA) of PEEK-Azadirachta indica reinforced at 10 wt%, 20 wt%, and 30 wt%.

Traumatic Dental Injuries and their Association with Demographics and Other Predisposing Risk Factors in School Children Aged between 8-13 Years: A Descriptive, Cross-Sectional Study.

Background: Traumatic dental injuries are most commonly seen in school age children. This not only affects physical, but, also, the psychological and social well-being of a child. The aim of the present study was to assess the prevalence of traumatic dental injuries in school children aged between 8 and 13 years and their association with the demographics and other predisposing risk factors.

Problem-Based Learning - An Overview.

The main objective of Problem-Based Learning (PBL) is to develop problem-solving skills, collaborative learning skills, self-directed learning skills, communication skills, deeper learning skills, lifelong learning skills, and better retention in the students to equip them better in their professional careers. Unlike the traditional curriculum which is mainly based on didactic lectures, PBL is based on a group of students working on a problem and solving it. PBL is a promising teaching and learning tool that can be adopted in all fields, especially in Medical and Dental curricula.

Comparative Evaluation of the Efficiency of Polymer Bur, Cera Bur, and Tungsten Carbide Bur in Dentin Caries Excavation of Mandibular Primary Molars: An Study.

Conservative caries removal has become an integral part of minimally invasive dentistry (MID). Polymer and Cera burs are two feasible MID methods. The aim of the study was to compare the efficiency of Polymer, Cera, and Tungsten carbide bur in dentin caries excavation of mandibular primary molars.