FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors.

To maintain both mitochondrial quality and quantity, cells selectively remove damaged or excessive mitochondria through mitophagy, which is a specialised form of autophagy. Mitophagy is induced in response to diverse conditions, including hypoxia, cellular differentiation and mitochondrial damage. However, the mechanisms that govern the removal of specific dysfunctional mitochondria under steady-state conditions to fine-tune mitochondrial content are not well understood.

Autophagy Inhibitor Chloroquine Downmodulates Hepatic Stellate Cell Activation and Liver Damage in Bile-Duct-Ligated Mice.

Hepatic stellate cell (HSC) activation via the autophagy pathway is a critical factor in liver fibrogenesis. This study tests the hypothesis that chloroquine (CQ) treatment can prevent autophagy and HSC activation in vitro and in vivo in bile-duct-ligated (BDL) mice. Sham-operated and BDL mice were treated with either PBS or CQ in two 60 mg/kg doses the day (D) before and after surgery.

Exosomes from adipose-derived stem cells promote angiogenesis and reduce necrotic grade in hindlimb ischemia mouse models.

Objectives: Acute hindlimb ischemia is a peripheral arterial disease that severely affects the patient's health. Injection of stem cells-derived exosomes that promote angiogenesis is a promising therapeutic strategy to increase perfusion and repair ischemic tissues. This study aimed to evaluate the efficacy of adipose stem cell-derived exosomes injection (ADSC-Exos) in treating acute mouse hindlimb ischemia.

Editorial: Role of Non-Coding RNAs in Animals.

The importance of non-coding RNAs (ncRNAs), such as microRNAs (miRNA), long non-coding RNAs (lncRNA), and circular RNAs (circRNA), in gene regulation is increasingly being appreciated in many species [...

Practical Synthesis of 1,4-Dihydropyridines on Heterogeneous Sulfonicmodified Silica (SBA-15-SOH) Catalyst Under Mild Condition.

Aims: Synthesis of 1,4-Dihydropyridines (1,4-DHP) using heterogeneous catalyst under mild condition.

Objective: Our objective is to explore new applications of non-metal heterogeneous catalysts in the synthesis of 1,4-DHP derivatives in a greener and more efficient approach.

Methods: A greener and more efficient method for the synthesis of 1,4-DHPs and an asymmetric 1,4-DHP (Felodipine drug) was successfully developed in high yields using a heterogeneous SBA- 15-SOH catalyst.

Association between nonalcoholic fatty liver disease and carotid intima-media thickness.

Background: Many non-invasive methods have been studied for assessing the severity of fatty liver disease and carotid intima-media thickness (CIMT). However, the correlation between hepatic steatosis and CIMT has not been fully studied, either globally or in Vietnam. This study investigated the association between nonalcoholic fatty liver disease (NAFLD) and CIMT.

The influence of economic and non-economic determinants on the sustainable energy consumption: evidence from Vietnam economy.

Maintaining ecological quality of energy use without compromising on economic growth has become the key research agenda of existing literature. Emerging economies are particularly facing this dual problem where they need to look in to the factors which impact sustainable energy consumption. The article, thus, aims to examine impact of economic and non-economic determinants on sustainable energy consumption in Vietnamese context.

Environmental Effects and Genetic Parameters for Growth Traits of Lohi Sheep.

Estimating genetic parameters for growth traits is crucial to plan breeding strategies for improving meat production in indigenous sheep breeds. The study first tested the effects of environmental and maternal effects on five growth traits, including birth weight (BWT), weight at 120 days (WT120), weight at 180 days (WT180), weight at 270 days (WT270) and weight at 365 days of age (WT365) and then estimated genetic parameters for these traits using data obtained in 1215 Lohi sheep. The effects of factors, including year (YOB), season (SOB) and type of birth (TOB), age of dam (AOD) and sex on growth traits of Lohi sheep, were examined using analysis of variance (ANOVA) in R software.

Correlation between nonalcoholic fatty liver disease and coronary atherosclerosis.

Background: Various non-invasive methods have been studied for assessing the severity of fatty liver disease and coronary atherosclero-sis. However, the correlation between hepatic steatosis and coronary atherosclerosis has not been fully studied, either globally or specifically in Vietnam. This study investigated the association between nonalcoholic fatty liver disease (NAFLD) and coronary atherosclerosis using coronary computed tomography angiography (CCTA).

Emerging Roles of Noncoding RNAs in Bovine Mastitis Diseases.

Non-coding RNAs (ncRNAs) are an abundant class of RNA with varying nucleotide lengths. They have been shown to have great potential in eutherians/human disease diagnosis and treatments and are now gaining more importance for the improvement of diseases in livestock. To date, thousands of ncRNAs have been discovered in the bovine genome and the continuous advancement in deep sequencing technologies and various bioinformatics tools has enabled the elucidation of their roles in bovine health.

Characterizations and antibacterial activities of passion fruit peel pectin/chitosan composite films incorporated leaf extract for preservation of purple eggplants.

The present study aimed to synthesize biodegradable films based on crosslinked passion fruit peel pectin/chitosan (P/CH) films incorporated with a bioactive extract from . leaf, and investigate their morphological, mechanical, water vapor permeability, optical, and antibacterial properties. The thickness and water vapor permeability of P/CH blend films were proportional to the increasing concentration of extract (PB).

Environmental innovation and firm value: The moderating role of organizational capital.

Since last decade, firms are facing the challenge of strict compliance in response to the stakeholders' awareness about climate change and environmental degradation. Considering these trends, we examine the effect of environmental innovation such as product innovation and process innovation on firm value and the moderating effect of organizational capital on environmental innovation-firm value nexus. Using the data of U.

Fabrication and characterization of polyamide thin-film composite membrane interfacial polycondensation for pervaporation separation of salt and arsenic from water.

Pervaporation, mainly utilized to separate azeotropic mixtures, has been paid much attention for desalination in recent years due to its numerous advantages. The membranes based on thin-film composite structure have gained great interest in pervaporation due to their thin thickness, controllable hydrophilicity, and crosslinking density which affects the permeation flux and selectivity of the membranes. In this study, a polyamide thin-film composite (PA-TFC) membrane was fabricated through interfacial polymerization between amine monomers and trimesoyl chloride (TMC) on a polysulfone porous substrate (PSf).

Stromal Vascular Fraction and Mesenchymal Stem Cells from Human Adipose Tissue: A Comparison of Immune Modulation and Angiogenic Potential.

Introduction: In recent years, both stromal vascular fraction (SVF) from adipose tissue and mesenchymal stem cells (MSC) from adipose tissues were extensively used in both preclinical and clinical treatment for various diseases. Some studies reported differences in treatment efficacy between SVFs and MSCs in animals as well as in humans. Therefore, this study is aimed to evaluate the immune modulation and angiogenic potential of SVFs and MSCs from the same SVF samples to support an explanation when SVFs or MSCs should be used.

How temperature shocks impact energy poverty in Vietnam: mediating role of financial development and environmental consideration.

This paper evaluates the energy poverty of Vietnam by mediating the role of financial development and environmental considerations. Across the globe, billions of individuals live in fuel poverty, failing to access inexpensive and sustainable energy, which is necessary for long-term development. An elevation in power consumption due to an overall increase in heat and short periods of extreme heat exacerbates global warming.

SME financing role in developing business environment and economic growth: empirical evidences from technical SMEs in Vietnam.

Distinguishing the significance of business environments for technical small and medium-sized enterprises (SMEs), this study examines the connection between business environments, GDP growth, and SMEs' financing choices in Vietnam. The study considered the agency theory as a theoretical base to explain how information asymmetry between SMEs and lenders influences SMEs' financing choices and encompasses the effects on business environment and GDP growth of Vietnam. For this binary logistic regression, text is applied.

Plastic waste as a valuable resource: strategy to remove heavy metals from wastewater in bench scale application.

Single-use plastic waste is gradually considered a potential material for circular economy. Ion exchange resin obtained from polystyrene waste by sulfonating with HSO was used for heavy metal removal from electroplating wastewater. Batch mode experiments of Cu, Zn, and Cd were carried out to determine effect of pH, initial concentration, equilibrium time, and the isotherm and kinetic parameters; the stability of the resin in continuous operation was then evaluated.

Inhibition of by a novel strain of isolated from the faeces of healthy chickens.

1. The objective of the study was to demonstrate that strain VL28 (BS-VL28), a novel strain isolated from faeces of healthy chicken, has potential as a probiotic.2.

Current application of algae derivatives for bioplastic production: A review.

Improper use of conventional plastics poses challenges for sustainable energy and environmental protection. Algal derivatives have been considered as a potential renewable biomass source for bioplastic production. Algae derivatives include a multitude of valuable substances, especially starch from microalgae, short-chain length polyhydroxyalkanoates (PHAs) from cyanobacteria, polysaccharides from marine and freshwater macroalgae.

Application of a Bayesian network to quantify human reliability in nuclear power plants based on the SPAR-H method.

Human error is an important factor leading to nuclear power plant (NPP) accidents. Human reliability analysis (HRA) is considered an effective method to reduce human error. Therefore, this article proposes a method to quantify human reliability based on the standardized plant analysis risk-human reliability analysis (SPAR-H) method.

Feto-Maternal Outcomes of Breastfeeding during Pregnancy: A Systematic Review and Meta-Analysis.

Background: Breastfeeding is beneficial to both mother and infant. However, overlap of lactation with pregnancy and short recuperative intervals may impact mothers nutritionally. We aimed to investigate the possible effects of pregnancy during breastfeeding.

Effect of ozonation on the biodegradability of urban wastewater treatment plant effluent.

The present work aimed to study the effect of ozonation on the organic sum parameters linked to enhanced biodegradability. Laboratory experiments were conducted with the effluent of four Austrian urban wastewater treatment plants with low food to microorganism ratios and different matrix characteristics. Biochemical oxygen demand over 5 days (BOD) was measured before ozonation and after application of different specific ozone doses (D) (0.

Anti-malarial activity in a Chinese herbal supplement containing Inonotus obliquus and Panax notoginseng.

Plasmodium falciparum, the most virulent human malaria parasite, causes serious diseases among the infected patients in the world and is particularly important in African regions. Although artemisinin combination therapy is recommended by the WHO for treatment of P. falciparum-malaria, the emergence of artemisinin-resistant parasites has become a serious issue which underscores the importance of sustained efforts to obtain novel chemotherapeutic agents against malaria.

Exploring the effects of road type on drivers' eye behavior and workload.

The number of traffic accidents is increasing every year. This study researched the effect of road type on driver's workload and eye behavior. The results showed that the road type has an effect on workload, pupil diameter, fixation rate and number of fixations.