Factors Associated with the Prolonged Use of Donor Human Milk at the Da Nang Hospital for Women and Children in Vietnam.

Background And Objectives: Donor human milk (DHM) from a human milk bank (HMB) is used to feed low-birthweight (LBW) and preterm infants when mothers cannot provide their own breastmilk. The misuse of DHM could interfere with mothers' breastmilk and weaken breastfeeding efforts. This study aimed to identify factors behind prolonged DHM usage during the first six years of Vietnam's first HMB.

Vitamin B, B, and B Intakes and Risk of Gastric Cancer: Findings from a Case-Control Study.

Background/objectives: Gastric cancer is one of the leading malignancies worldwide. B vitamins play important roles in DNA synthesis and methylation because they are considered co-enzymes in one-carbon metabolism. There is inconclusive evidence regarding the associations between dietary vitamins B, B, and B with the risk of gastric cancer in different epidemiologic studies.

Newcastle Disease Virus-Vectored African Swine Fever Virus Antigen Cocktail Delays the Onset of ASFV-SY18 but Is Not Protective.

African Swine Fever (ASF) is a highly contagious viral disease threatening the global pig industry. Currently, only two gene-deleted live attenuated vaccines are approved, exclusively in Vietnam, and their long-term effectiveness and safety are unproven, prompting the need for safer alternatives. This study assessed a cocktail of African Swine Fever Virus (ASFV) antigens delivered via a recombinant Newcastle Disease Virus (rNDV) vector against the genotype II ASFV-SY18.

Carotenoid Interactions with PCSK9: Exploring Novel Cholesterol-Lowering Strategies.

: This study investigated the potential of green algae-derived carotenoids as natural inhibitors of the proprotein convertase subtilisin/kexin type 9 (PCSK9), a key regulator of cholesterol metabolism. PCSK9 promotes the degradation of low-density lipoprotein receptors (LDLR), thereby increasing blood cholesterol levels and elevating the risk of cardiovascular diseases. /: We screened the pharmacophore fit score of 27 carotenoids with PCSK9 and identified 14 that were analyzed for binding affinity and molecular interactions.

Modulatory Effect of Cucurbitacin D from on ZNF217 Oncogene Expression in NPM-Mutated Acute Myeloid Leukemia.

The expression of oncogene zinc-finger protein 217 (ZNF217) has been reported to play a central role in cancer development, resistance, and recurrence. Therefore, targeting ZNF217 has been proposed as a possible strategy to fight cancer, and there has been much research on compounds that can target ZNF217. The present work investigates the chemo-preventive properties of cucurbitacin D, a compound with a broad range of anticancer effects, in hematological cancer cells, specifically with regard to its ability to modulate ZNF217 expression.

Biosensors for Seafood Safety Control-A Review.

The increased demand for consuming seafood has made seafood production undergo a rapid period of growth. However, seafood has a high risk of contamination from harmful microorganisms and marine toxins which can cause health problems for humans consuming it. Concerning this issue, monitoring seafood safety has become a center of attention for researchers, and developing effective methods for detecting contamination in seafood has become a critical research field.

Advancements in Mass Spectrometry-Based Targeted Metabolomics and Lipidomics: Implications for Clinical Research.

Targeted metabolomics and lipidomics are increasingly utilized in clinical research, providing quantitative and comprehensive assessments of metabolic profiles that underlie physiological and pathological mechanisms. These approaches enable the identification of critical metabolites and metabolic alterations essential for accurate diagnosis and precision treatment. Mass spectrometry, in combination with various separation techniques, offers a highly sensitive and specific platform for implementing targeted metabolomics and lipidomics in clinical settings.

Disentangling Taxonomic Confusions in the Group Using Mitochondrial Genomic Data (Lepidoptera: Pieridae).

Pierid species of the group are among the largest Sino-Himalayan members of genus , with four conventionally recognised species, namely , , , and . Recent publications indicated that some of these species may contain more than one species despite their similar morphological characters. The present research analysed this group of butterflies using mitogenomic data, and proved that , , , and should be recognised as distinct species, while , and should be subspecies of .

Assessment of the Potential Suitable Habitat of Chevrolat, 1852 (Coleoptera: Cerambycidae) Under Climate Change and Human Activities Based on the Biomod2 Ensemble Model.

Effective use of species distribution models can assess the risk of spreading forest pests. In this study, based on 434 occurrence records and eight environmental variables, an ensemble model was applied to identify key environmental factors affecting the distribution of Chevrolat, 1852 and predict its potential habitat and its relative areas of change under current and future climatic conditions. The results indicate that humidity, solar radiation, topography, and human activities were the main factors influencing the distribution of .

A Higher Charlson Comorbidity Index Is a Risk Factor for Hip Fracture in Older Adults During Low-Temperature Periods: A Cross-Sectional Study.

: The incidence of hip fractures is increasing, and there have been reports linking cold weather to a higher risk of fractures. This study aimed to evaluate clinical variables in hip fracture patients who may predispose them to such fractures under different temperatures. : This is a cross-sectional study conducted at a single medical center, enrolling older adults (≥60 years) who had experienced a hip fracture.

Immunohistochemical Evaluation of Basal and Luminal Markers in Bladder Cancer: A Study from a Single Institution.

Background: Bladder cancer (BC) presents significant molecular diversity, which affects both prognosis and treatment results. Immunohistochemistry (IHC) facilitates the identification of molecular subtypes and their relationships with clinicopathological features.

Methods: We performed an IHC analysis on tissue samples from 107 BC patients, evaluating the expression of markers GATA3, CD44, CK5/6, and CK20.

Optimization of Culture Conditions for High Cell Productivity and Astaxanthin Accumulation in Vietnam's Green Microalgae HB and a Neuroprotective Activity of Its Astaxanthin.

Background: , a green microalga, is a rich source of natural astaxanthin and a potent antioxidant with high commercial value. This study investigates the biological characteristics and potential of HB isolated from Hoa Binh, Vietnam, for growth and astaxanthin accumulation using a two-phase culture method.

Methods: HB was cultured in a C/RM medium at 25 °C, and morphological characteristics were examined.

Adherence to Pulmonary Tuberculosis Medication and Associated Factors Among Adults: A Cross-Sectional Study in the Metinaro and Becora Sub-Districts, Dili, Timor-Leste.

Timor Leste is one of the top countries in Asia with a high incidence rate of pulmonary tuberculosis (TB). The success of TB treatment necessitated a more profound comprehension of adherence as a multifaceted behavioral issue, along with identifying the barriers that hinder and the factors that promote patient adherence. This study aimed to assess the rate of pulmonary TB medication adherence and identify its predictors among adults in Metinaro and Becora, Dili, Timor-Leste.

The Impact of Vaccination on COVID-19 Outcomes in Vietnam.

: This study aimed to assess the effectiveness of the COVID-19 vaccine on the outcomes of patients in three hospitals in Vietnam. : An observational study involved 3102 confirmed COVID-19 patients from Vietnam. Participants were classified into unvaccinated, partially vaccinated (one dose) (PV), fully vaccinated (two doses) (FV), and boosted (three doses) groups.

Correction: Telesca et al. Visibility Graph Analysis of Reservoir-Triggered Seismicity: The Case of Song Tranh 2 Hydropower, Vietnam. 2022, , 1620.

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Deciphering the Liaison Between Fine Particulate Matter Pollution, Oxidative Stress, and Prostate Cancer: Where Are We Now?

Prostate cancer (PCa), a highly prevalent cancer in men worldwide, is projected to rise in the coming years. As emerging data indicate the carcinogenic effects of fine particulate matter (PM2.5) in lung cancer and other site-specific cancers, there is an urgent need to evaluate the relationship between this environmental risk factor and PCa as a potential target for intervention.

Can Different Dietary Protein Sources Influence the Survival, Growth, and Physiology of 0Marron () Exposed to Feed Deprivation?

We investigated the effect of feed deprivation for 45 days on the growth, immunity, and health of 0marron () initially fed for 110 days on various protein sources including fishmeal (FM), poultry by-product meal (PBM), black soldier fly meal (BSFM), soybean meal (SBM), lupin meal (LM), and tuna hydrolysate. The marron were weighed and sacrificed immediately after feeding stopped (day 0) and at days 15, 30, and 45 after the feed deprivation trial commenced. Total haemolymph count, differential haemocyte count, lysozyme activity, protease activity, total bacterial count in the digestive tract, and organosomatic indices were analysed.

Development of a bioreactor with an integrated non-dispersive infrared CO sensor for rapid and sensitive detection of Cr(VI) toxicity in water.

Whole-cell bioreactors equipped with external physico-chemical sensors have gained attention for real-time toxicity monitoring. However, deploying these systems in practice is challenging due to potential interference from unknown wastewater constituents with liquid-contacted sensors. In this study, a novel approach using a bioreactor integrated with a non-dispersive infrared CO₂ sensor for both toxicity detection and real-time monitoring of microbial growth phases was successfully demonstrated.

Identification of DNA methylation signatures in follicular-patterned thyroid tumors.

Background And Aims: Follicular-patterned thyroid tumors (FPTTs) are frequently encountered in thyroid pathology, encompassing follicular adenoma (FA), follicular thyroid carcinoma (FTC), noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP), and follicular variant of papillary thyroid carcinoma (fvPTC). Recently, a distinct entity termed differentiated high-grade thyroid carcinoma has been described by the 5th edition of the WHO classification of the thyroid tumors, categorized as either high-grade fvPTC, high-grade FTC or high-grade oncocytic carcinoma of the thyroid (OCA). Accurate differentiation among these lesions, particular between the benign (FA), borderline (NIFTP) and malignant neoplasms (FTC and fvPTC), remains a challenge in both histopathological and cytological diagnoses.

Action and immunomodulatory mechanisms, formulations, and safety concerns of probiotics.

The global probiotics market has been continuously growing, driven by consumer demand for immune-enhancing functional foods, dietary supplements, and natural therapeutics for gastrointestinal and gut function-mediated diseases. Probiotic microorganisms represent a diverse group of strains with complex but generalized mechanistic patterns. This review describes the various immunomodulatory mechanisms by which probiotics exert their effects, including the competitive exclusion of pathogenic microbes, production of antimicrobial substances, modulation of the immune system, and improvement of gut barrier function.

A Predictive Nomogram for Selective Screening of Chronic Kidney Disease: A Population-Based Study.

Objectives: Chronic kidney disease (CKD) is associated with disability, low quality of life, and mortality. However, most cases are asymptomatic, often detected incidentally, or only recognized when they have progressed to the later stages with complications. The present study aimed to determine the prevalence of CKD and develop a predictive nomogram for CKD in Vietnamese adults.

Unlocking new possibility of FeO@C@Ag nanostructures as an advanced SERS substrate for ultrasensitive detection of low-cross-section urea biomolecules.

Surface-enhanced Raman spectroscopy (SERS) is widely recognized as a powerful analytical technique, offering molecular identification by amplifying characteristic vibrational signals, even at the single-molecule level. While SERS has been successfully applied for a wide range of targets including pesticides, dyes, bacteria, and pharmaceuticals, it has struggled with the detection of molecules with inherently low Raman scattering cross-sections. Urea, a key nitrogen-containing biomolecule and the diamide of carbonic acid, is a prime example of such a challenging target.

Psychometric properties of the health literacy questionnaire tested in Vietnamese adults with chronic diseases.

Background: The Health Literacy Questionnaire (HLQ) is an increasingly used health literacy instrument that has been translated into many languages. The HLQ has 44 items and comprises 9 scales assessing the multidimensional construct of health literacy. This study reports the HLQ reliability and construct validity tested in people with chronic diseases living in Vietnam.

Adherence to guidelines for natriuretic peptide testing in heart failure: a nationwide survey of healthcare professionals in Vietnam.

Objectives: This study aimed to determine doctors' level of adherence to the natriuretic peptide testing guideline and to identify the factors influencing their adherence.

Design: Cross-sectional study.

Setting: Web-based survey.